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918 Articles

Hydrogen-rich water achieves cytoprotection from oxidative stress injury in human gingival fibroblasts in culture or 3D-tissue equivalents, and wound-healing promotion, together with ROS-scavenging and relief from glutathione diminishment.

By H2HUBB Jul 22, 2026 0 Comments

In The in vitro scratch assay showed that HW was able to diminish physical injury-induced ROS generation and promote wound healing in HGF cell monolayer sheets, lIVE/DEAD staining and the authors' original cell viability dye-extraction assay showed that HW significantly protected HGF…

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Positive Effects of hydrogen water on 2,4-dinitrochlorobenzene-induced atopic dermatitis in NC/Nga mice.

By H2HUBB Jul 22, 2026 0 Comments

In mice, the levels of Th2 cytokine, interleukin-5 (IL-5), and proinflammatory cytokines such as tumor necrosis factor-α and IL-6 in HW-fed mice were significantly lower than in control…

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Topically Applied Molecular Hydrogen Normalizes Skin Parameters Associated with Oxidative Stress: A Pilot Study.

By H2HUBB Jul 22, 2026 0 Comments

In 15 participants, the hypothesis was that H₂, through its selective antioxidant and anti-inflammatory properties, would reduce oxidative stress, modulate inflammatory pathways, and enhance skin barrier integrity, leading…

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Hydrogen ameliorates psoriasis-like skin inflammation via inhibiting the cGAS-STING pathway.

By H2HUBB Jul 22, 2026 0 Comments

In an animal model, consistently, hydrogen decreased proliferative marker expression, including BCL2, BAX, and Ki-67, and significantly reduced ROS and inflammatory cytokines production. These preclinical findings add evidence…

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Progress in the Application of Molecular Hydrogen in Medical Skin Cosmetology.

By H2HUBB Jul 22, 2026 0 Comments

In a study on a squamous cell carcinoma model in mice, Dole et al 68 conducted a high-pressure hydrogen treatment and found that mice with skin squamous cell…

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Intermittent environmental exposure to hydrogen prevents skin photoaging through reduction of oxidative stress.

By H2HUBB Jul 22, 2026 0 Comments

In a laboratory model, detected attenuation of DNA damage in the hydrogen exposure group as indirect evidence that intermittent exposure to hydrogen gas reduced oxidative stress. The authors…

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Effect and mechanism of hydrogen-rich bath on mice with imiquimod-induced psoriasis.

By H2HUBB Jul 22, 2026 0 Comments

In mice, by naked eye, the severity of skin lesions in hydrogen-rich water bath group was lower than that in distilled water bath group, and the psoriasis severity…

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Local Treatment of Hydrogen-Rich Saline Promotes Wound Healing In Vivo by Inhibiting Oxidative Stress via Nrf-2/HO-1 Pathway.

By H2HUBB Jul 22, 2026 0 Comments

In mice, local treatment of hydrogen-rich water shortened wound closure time and reduced the level of proinflammatory cytokines and lipid peroxidation. These preclinical findings add evidence supporting molecular…

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Hydrogen-generating Si-based agent protects against skin flap ischemia-reperfusion injury in rats.

By H2HUBB Jul 22, 2026 0 Comments

In rats, the Si-based agent was found to effectively suppress I/R injury in skin flaps, and allow for the production of a large amount of hydrogen continuously via…

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Prophylactic Instillation of Hydrogen-Rich Water Decreases Corneal Inflammation and Promotes Wound Healing by Activating Antioxidant Activity in a Rat Alkali Burn Model.

By H2HUBB Jul 22, 2026 0 Comments

In rats, prophylactic instillation of hydrogen suppressed alkali burn-induced oxidative stress of the cornea and promoted wound healing. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential…

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Antioxidant Activity of Hydrogen Water Mask Pack Composed of Gel-Type Emulsion and Hydrogen Generation Powder.

By H2HUBB Jul 22, 2026 0 Comments

For the Zn-500 sample, the hydrogen concentration increased to 0.02 and 0.551 ppm after 30 min and 3 h, respectively, and subsequently decreased to 0.031 ppm after 24…

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The Therapeutic Effects of Oral Intake of Hydrogen Rich Water on Cutaneous Wound Healing in Dogs.

By H2HUBB Jul 22, 2026 0 Comments

In dogs, HRW treatment promoted skin wound healing in dogs, accelerated wound epithelization, reduced inflammatory reaction, stimulated the expression of cytokines related to wound healing, and shortened wound…

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Hydrogen-rich saline reduces tissue injury and improves skin flap survival on a rat hindlimb degloving injury model.

By H2HUBB Jul 22, 2026 0 Comments

In Sprague-Dawley rats, repeated HRS injections after trauma increased the viability of skin flap in rat degloving injury model by decreasing local tissue injury, due to its antioxidant,…

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The protective effects of molecular hydrogen in sepsis-associated encephalopathy: current status.

By H2HUBB Jul 22, 2026 0 Comments

This narrative review examined the available molecular-hydrogen literature. This review synthesises the current evidence on H₂ therapy in SAE and highlights key directions for future research, focusing on…

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Hydrogen alleviates mitochondrial dysfunction and organ damage via autophagy‑mediated NLRP3 inflammasome inactivation in sepsis.

By H2HUBB Jul 22, 2026 0 Comments

In The cells were resuspended in DMEM supplemented with 10% (v/v) FBS, 1% (v/v) penicillin and streptomycin to adjust the cell density to 1.5×10 6 /ml, H₂ alleviated…

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