Hydrogen ameliorates psoriasis-like skin inflammation via inhibiting the cGAS–STING pathway

This animal study examined Hydrogen ameliorates psoriasis-like skin inflammation via inhibiting the cGAS–STING pathway | Clinical and Experimental Immunology | Oxford Academic. The abstract describes Mouse model; hydrogen delivered as hydrogen water and topical hydrogen. The abstract reports: In a previous study, we demonstrated in a psoriasis mouse model that hydrogen-rich water, an effective reactive oxygen species (ROS) scavenger, significantly improves disease…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Intermittent environmental exposure to hydrogen prevents skin photoaging through reduction of oxidative stress.

This animal study examined Intermittent environmental exposure to hydrogen prevents skin photoaging through reduction of oxidative stress. The abstract describes Mouse model. The abstract reports: Our findings support the notion that long-term, intermittent environmental exposure to hydrogen gas in daily life has a beneficial effect on UVA-induced photoaging. Geriatr…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Local Treatment of Hydrogen-Rich Saline Promotes Wound Healing In Vivo by Inhibiting Oxidative Stress via Nrf-2/HO-1 Pathway.

This animal study examined Local Treatment of Hydrogen-Rich Saline Promotes Wound Healing In Vivo by Inhibiting Oxidative Stress via Nrf-2/HO-1 Pathway. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: The results showed that local treatment of hydrogen-rich saline shortened wound closure time and reduced the level of proinflammatory cytokines and lipid peroxidation. This is an automated editorial draft based on the abstract and requires source review before publication.

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Prophylactic Instillation of Hydrogen-Rich Water Decreases Corneal Inflammation and Promotes Wound Healing by Activating Antioxidant Activity in a Rat Alkali Burn Model.

This animal study examined Prophylactic Instillation of Hydrogen-Rich Water Decreases Corneal Inflammation and Promotes Wound Healing by Activating Antioxidant Activity in a Rat Alkali Burn Model. The abstract describes Rat model; hydrogen delivered as hydrogen water; reported duration 5 min. The abstract reports: Many studies have demonstrated the therapeutic effects of hydrogen in pathological conditions such as inflammation; however, little is known about its prophylactic effects. This is an automated editorial draft based on the abstract and requires source review before publication.

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Antioxidant Activity of Hydrogen Water Mask Pack Composed of Gel-Type Emulsion and Hydrogen Generation Powder.

This uncontrolled human study examined Antioxidant Activity of Hydrogen Water Mask Pack Composed of Gel-Type Emulsion and Hydrogen Generation Powder. The abstract describes Human participants; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen Gas Protects Against Intestinal Injury in Wild Type But Not NRF2 Knockout Mice With Severe Sepsis by Regulating HO-1 and HMGB1 Release.

This animal study examined Hydrogen Gas Protects Against Intestinal Injury in Wild Type But Not NRF2 Knockout Mice With Severe Sepsis by Regulating HO-1 and HMGB1 Release. The abstract describes Mouse model. The abstract reports: The results showed that therapy with 2% H2 increased the survival rate, alleviated the injuries caused by oxidative stress and inflammation, reduced HMGB1 levels…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effects of hydrogen gas on murine polymicrobial sepsis via reducing oxidative stress and HMGB1 release.

This uncontrolled human study examined Protective effects of hydrogen gas on murine polymicrobial sepsis via reducing oxidative stress and HMGB1 release. The abstract describes Human participants. The abstract reports: Recently, it has been suggested that molecular hydrogen (H2) exerts a therapeutic antioxidant activity by selectively reducing hydroxyl radicals (*OH, the most cytotoxic reactive…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas therapy: A promising approach for sepsis management post-burn injury by modulating inflammation, oxidative stress, and wound healing.

This uncontrolled human study examined Hydrogen gas therapy: A promising approach for sepsis management post-burn injury by modulating inflammation, oxidative stress, and wound healing. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: Wound healing was monitored, with wound contraction rates recorded and histological assessments conducted using hematoxylin and eosin and Masson's trichrome staining to evaluate tissue…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen: a therapeutic antioxidant and beyond.

This uncontrolled human study examined Molecular hydrogen: a therapeutic antioxidant and beyond. The abstract describes Human participants. The abstract reports: Emerging evidence has consistently demonstrated that molecular hydrogen is a promising therapeutic option for a variety of diseases and the underlying comprehensive mechanisms is…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular Hydrogen Ameliorates Anti-Desmoglein 1 Antibody-Induced Pemphigus-Associated Interstitial Lung Disease by Inhibiting Oxidative Stress.

This uncontrolled human study examined Molecular Hydrogen Ameliorates Anti-Desmoglein 1 Antibody-Induced Pemphigus-Associated Interstitial Lung Disease by Inhibiting Oxidative Stress. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: Using a BALB/cJGpt mouse model, we demonstrated that anti-Dsg 1 antibodies, but not anti-Dsg 3 antibodies, induced interstitial inflammation and fibrosis. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas reduces HMGB1 release in lung tissues of septic mice in an Nrf2/HO-1-dependent pathway.

This uncontrolled human study examined Hydrogen gas reduces HMGB1 release in lung tissues of septic mice in an Nrf2/HO-1-dependent pathway. The abstract describes Human participants. The abstract reports: The results indicated that 2% H gas treatment increased the survival rates, decreased the W/D weight ratio and the lung injury score, alleviated the…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen Gas Inhalation Attenuates Seawater Instillation-Induced Acute Lung Injury via the Nrf2 Pathway in Rabbits.

This animal study examined Hydrogen Gas Inhalation Attenuates Seawater Instillation-Induced Acute Lung Injury via the Nrf2 Pathway in Rabbits. The abstract describes Rabbit model; hydrogen delivered as hydrogen inhalation. The abstract reports: These results demonstrate that hydrogen gas inhalation attenuates seawater instillation-induced acute lung injury in rabbits and that the protective effects observed may be related…. This is an automated editorial draft based on the abstract and requires source review before publication.

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High concentration of hydrogen gas alleviates Lipopolysaccharide-induced lung injury via activating Nrf2 signaling pathway in mice.

This animal study examined High concentration of hydrogen gas alleviates Lipopolysaccharide-induced lung injury via activating Nrf2 signaling pathway in mice. The abstract describes Mouse model. The abstract reports: HCH can effectively alleviate LPS-induced ALI, which may be related to activation of Nrf2 signaling pathway and inhibition of inflammatory response and cell apoptosis…. This is an automated editorial draft based on the abstract and requires source review before publication.

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The use of ultrapure molecular hydrogen enriched with atomic hydrogen in apparatuses of artificial lung ventilation in the fight against virus COVID-19.

This uncontrolled human study examined The use of ultrapure molecular hydrogen enriched with atomic hydrogen in apparatuses of artificial lung ventilation in the fight against virus COVID-19. The abstract describes Human participants; hydrogen delivered as oxyhydrogen. The abstract reports: Many studies have been carried out that have demonstrated that hydrogen has strong anti-inflammatory properties. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen Attenuates Endotoxin-Induced Lung Injury by Activating Thioredoxin 1 and Decreasing Tissue Factor Expression.

This animal study examined Hydrogen Attenuates Endotoxin-Induced Lung Injury by Activating Thioredoxin 1 and Decreasing Tissue Factor Expression. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: LPS-stimulated THP-1 and HUVEC-C cells and showed that hydrogen decreases TF expression and MMP-9 activity, which were abolished by the Trx1 inhibitor, PX12. This is an automated editorial draft based on the abstract and requires source review before publication.

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