Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In female C57BL/6 mice, at the molecular level, HRW reduced spinal oxidative stress and ERK-dependent plasticity without altering spinal NLRP3 expression, whereas it fully reversed NLRP3 upregulation and HO-1 downregulation in the amygdala. These preclinical findings add evidence supporting molecular hydrogen's therapeutic…
Read ArticleIn an animal model, consumption of hydrogen water ad libitum throughout the whole period suppressed the increase in the oxidative stress markers and prevented cognitive impairment, as judged…
Read ArticleIn pregnant mice fed a diet containing the Si-based agent, lipopolysaccharide (LPS)-induced miscarriage due to mother-to-child transmission was reduced and inflammation and neutrophil infiltration in the placenta were…
Read ArticleIn rats, H₂ significantly attenuated hydrogen peroxide-induced sFlt-1 expression, but could not reduce the expression induced by hypoxia in BeWo cells. These preclinical findings add evidence supporting molecular…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. The present review evaluates the concept of 'hydrogen resuscitation', based on knowledge that hydrogen treatment effectively protects cells, tissues and…
Read ArticleIn rats, concluded that HRW protects the neurons against lead-induced oxidative stress and has anti-apoptotic effects without a noticeable change in NO level which already was diminished by…
Read ArticleIn mice, plasma creatine kinase activities were decreased by hydrogen at ages 10 and 24 weeks. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Molecular hydrogen (H₂) has been accepted to be an inert and nonfunctional molecule in the authors' body. The reviewed evidence…
Read ArticleIn mice, the authors' recent studies provided evidence that hydrogen inhalation can selectively reduce cytotoxic oxygen radicals and exert antioxidant effects. These preclinical findings add evidence supporting molecular…
Read ArticleIn male Wistar rats, each hydrogen-rich liquid resuscitation preparation could protect the lung against acute injury secondary to UHS. These preclinical findings add evidence supporting molecular hydrogen's therapeutic…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. In conclusion, a substantial body of experimental evidence suggests that hydrogen can significantly alleviate transplantation-related ischemia-reperfusion injury and have a…
Read ArticleIn a laboratory model, electrolyzed Reduced Water (ERW) produced near the cathode during water electrolysis exhibits high pH, high concentration of dissolved hydrogen and an extremely negative redox…
Read ArticleIn a laboratory model, examined the neuroprotective effects of molecular hydrogen and Pt NPs and showed that both molecular hydrogen and Pt NPs contributed to the neuroprotective effects…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. A recent study provided evidence that hydrogen inhalation exerted antioxidant and anti-apoptotic effects and protected the brain against ischemia-reperfusion injury…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. The authors highlighted early evidence of cytoprotective, antioxidant, and anti-inflammatory effects. The reviewed evidence adds support for molecular hydrogen's therapeutic…
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