Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In mice, although sulfasalazine significantly reduced MDA levels compared to the colitis model (P < 0.001), H₂ with and without sulfasalazine was significantly more effective compared to sulfasalazine treatment (P < 0.001), and essentially prevented the DSS-induced MDA increase. These preclinical findings…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
Read ArticleIn male Wistar rats, the serum levels of TNF-α, IL-1β, and IL-6 were significantly increased 12 h after the onset of AP ( Fig 3A ), and the…
Read ArticleIn rats, hydrogen-rich saline also increased B-cell lymphoma 2 (Bcl-2) expression and the activity of the antioxidant enzyme superoxide dismutase (SOD). These preclinical findings add evidence supporting molecular…
Read ArticleIn rats, HRW treatment effectively alleviated the degenerative changes in the retinal outer nuclear layer, improved retinal function, and reduced retinal inflammation in treated rats. These preclinical findings…
Read ArticleIn mice, H₂ mice showed significantly higher retinal thickness as compared to controls on optical coherence tomography. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within…
Read ArticleThe researchers found that hydrogen decreased the expression of the DNA damage-related protein ATM, cyclinD1 and NF-κB but increased the expression of the DNA repair-related protein HMGB1, suggesting…
Read ArticleIn guinea pigs, compared with the glutamate-induced injury group, the hydrogen-rich saline treatment reduced the loss of cells in the GCL and thinning of the retina and attenuated…
Read ArticleIn rats, s-nitroso-N-acetylpenicillamine treatment decreased the cell numbers in the ganglion cell layer and inner nuclear layer, but the presence of H₂ inhibited this reduction. These preclinical findings…
Read ArticleIn One day after I/R injury, apoptotic cells in the retina were quantified, and oxidative stress was evaluated by markers such as 4-hydroxynonenal and 8-hydroxy-2-deoxyguanosine, when H(2)-loaded eye…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
Read ArticleIn rats, fIGURE 4 Hydrogen rich saline induced effects on the oxygen stress markers of MNU administered rats. (A) The SOD level of the untreated group was significantly…
Read ArticleIn male Sprague-Dawley rats, molecular hydrogen (H₂) has been widely reported to have benefiicial effects in diverse animal models and human disease through reduction of oxidative stress and…
Read ArticleThis animal study examined Therapeutic effect of molecular hydrogen in corneal UVB-induced oxidative stress and corneal photodamage. The abstract describes Rabbit model. The abstract reports: We previously found…
Read ArticleThis animal study examined Hydrogen saline treatment attenuates hyperoxia-induced retinopathy by inhibition of oxidative stress and reduction of VEGF expression. The abstract describes Mouse model; hydrogen delivered as…
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