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In rats, although enhanced MDA levels were observed in all of the injured animals, the elevation appeared to be significantly inhibited by hydrogen-rich saline treatment ( P < 0.05; Figure 4(a) ). These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
Read ArticleIn Sprague-Dawley rats, the serum tumor necrosis factor-α content increased significantly in I/R + saline group, but HRW treatment reduced serum tumor necrosis factor-α content as compared to…
Read ArticleIn male Sprague-Dawley rats, hydrogen-rich saline reduced these markers and relieved morphological intestinal injury, while no significant reduction was observed in the nitrogen-rich saline-treated animals. These preclinical findings…
Read ArticleIn rats, experimental protocols were divided into four groups: sham operation group, no luminal injection (control) group, luminal injection of 5% glucose saline (GS) solution group, and luminal…
Read ArticleIn rats, histopathological mucosal erosion and increased gut permeability indicated a breakdown in posttransplant mucosal barrier function which was significantly attenuated by hydrogen treatment. These preclinical findings add…
Read ArticleIn Here, the researchers investigated whether ex vivo donor organ treatment with dissolved hydrogen would prevent intestinal graft injury, reflecting improved graft preservation, hydrogen preloading of grafts increased…
Read ArticleIn Sprague-Dawley rats, hRS treatment maintained the body weight, reduced the incidence of NEC from 85% (17/20) to 54.5% (12/22), increased the survival rate from 25% (5/20) to…
Read ArticleIn rats, treatment with hydrogen-rich saline reduced the weight loss and diarrhea and alleviated the colonic mucosal damage in the UC rats. These preclinical findings add evidence supporting…
Read ArticleThe researchers showed that 8-OHdG, but not MDA, significantly increased by 149% and 145% in HU-NW and HU-AEW, respectively, when compared with CONT. These preclinical findings add evidence…
Read ArticleIn mice, table 1 Effects of molecular hydrogen-dissolved alkaline electrolyzed water on physical parameters at 4 weeks of treatment Biochemical parameters of the serum obtained from mice administered…
Read ArticleIn mice, the pivotal proteins involved in endoplasmic reticulum (ER) stress, including p-eIF2α, ATF4, XBP1s and CHOP, were dramatically reduced after HRW treatment in contrast to the control…
Read ArticleIn rats, the oxidative stress levels of MDA and MPO in the gastric tissues increased significantly in the aspirin-treated group compared with the HRW group (2.43 ± 0.145…
Read ArticleIn an animal model, body mass was 36.4 (35.1–37.9) and 36.9 (34.4–38.4) kg in the control and hydrogen groups, respectively ( p = 0.89). These preclinical findings add…
Read ArticleIn the intestinal tissue, compared with the LPS group, the HRW + LPS group had decreased the levels of IL-1β and TNF-α ( Figure 2 B, p <…
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