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Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In male Sprague-Dawley rats, as shown in Figure 6B, the Nrf2 protein level increased significantly in the CS-challenged rat lungs as compared with that in the control (p<0.01), while hydrogen-rich saline pretreatment resulted in a significant reduction of Nrf2 protein as compared…
Read ArticleIn rats, hydrogen inhalation significantly reduced the number of inflammatory cells in the bronchoalveolar lavage fluid, and the mRNA and protein expression levels of tumor necrosis factor alpha,…
Read ArticleIn mice, hydrogen gas inhalation markedly upregulated the activity of decreased superoxide dismutase and significantly attenuated the increased level of malondialdehyde and myeloperoxidase. These preclinical findings add evidence…
Read ArticleIn an animal model, administration of H₂-rich water attenuated the CS-induced lung damage in the SMP30-KO mice and reduced the mean linear intercept and destructive index of the…
Read ArticleIn mice, combination treatment with inhaled NO and H₂ could also significantly attenuate lung injury in polymicrobial sepsis. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential…
Read ArticleIn a laboratory model, western blot analysis showed that hydrogen significantly upregulated the levels of phosphorylated AMPK (p-AMPK) and lowered the LPS-induced increased expression of dynamin-related protein 1…
Read ArticleThis narrative review examined the present review aims to provide a consistent summary of the findings of the last twenty years on the use of molecular hydrogen in…
Read ArticleIn 10 patients with chronic lung diseases due to COPD (n = 7), however, vitamin E, vitamin C, and nitrite levels showed a significant increase after 4 week…
Read ArticleThis publication is an erratum or correction associated with a molecular-hydrogen article. It does not report a new standalone experiment.
Read ArticleIn A549 and NCI-H292 cells utilized in this study were obtained from the Korean Cell Line Bank (Cancer Research Institute of Seoul National University, Seoul, Korea), H₂O₂ stimulation…
Read ArticleIn a laboratory model, hydrogen ameliorated cell injury and enhanced mitophagy in macrophages stimulated by LPS. The authors concluded that these results suggest that PINK1-mediated mitophagy plays a…
Read ArticleIn a mouse model of lipopolysaccharide-induced acute lung injury, inhalation of 66.7% hydrogen reduced lung pathological changes, pulmonary edema, pro-inflammatory cytokine release and oxidative-stress responses. These preclinical findings…
Read ArticleIn an animal model, however, BLM-induced oxidative stress was attenuated by H₂ inhalation therapy, which reduced the contents of reactive oxygen species, malondialdehyde and hydroxyproline, enhanced the activity…
Read ArticleIn mice, within 1 wk after whole thorax irradiation, immunohistochemistry and immunoblotting showed that H(2) treatment reduced oxidative stress and apoptosis, measures of acute damage, in the lungs…
Read ArticleIn 120 patients with CR were randomly divided into two groups, compared to saline irrigation, HRS nasal irrigation was found to improve CR clinical symptoms, especially in patients…
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