Hydrogen alleviates cell damage and acute lung injury in sepsis via PINK1/Parkin-mediated mitophagy
This animal study examined Hydrogen alleviates cell damage and acute lung injury in sepsis via PINK1/Parkin-mediated mitophagy. The abstract describes Mouse model. The abstract reports: These results suggest that PINK1-mediated mitophagy plays a key role in the protective effects of hydrogen against cell injury in LPS-induced inflammation and CLP-induced…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHigh concentration of hydrogen ameliorates lipopolysaccharide-induced acute lung injury in a sirt1-dependent manner
This animal study examined High concentration of hydrogen ameliorates lipopolysaccharide-induced acute lung injury in a sirt1-dependent manner. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: Results showed that 66.7 % hydrogen alleviated lung pathological changes and pulmonary edema caused by LPS, and reduced the degree of ALI by inhibiting…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation attenuated bleomycin‐induced pulmonary fibrosis by inhibiting transforming growth factor‐β1 and relevant oxidative stress and epithelial‐to‐mesenchymal transition
This uncontrolled human study examined Hydrogen inhalation attenuated bleomycin‐induced pulmonary fibrosis by inhibiting transforming growth factor‐β1 and relevant oxidative stress and epithelial‐to‐mesenchymal transition. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: • What is the central question of this study? The aim was to explore the effects and underlying mechanisms of H on bleomycin-induced pulmonary…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen therapy attenuates irradiation-induced lung damage by reducing oxidative stress.
This animal study examined Hydrogen therapy attenuates irradiation-induced lung damage by reducing oxidative stress. The abstract describes Mouse model. The abstract reports: Within 1 wk after whole thorax irradiation, immunohistochemistry and immunoblotting showed that H(2) treatment reduced oxidative stress and apoptosis, measures of acute damage, in…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-oxygen therapy alleviates clinical symptoms in twelve patients hospitalized with COVID-19: A retrospective study of medical records.
This observational study examined Hydrogen-oxygen therapy alleviates clinical symptoms in twelve patients hospitalized with COVID-19: A retrospective study of medical records. The abstract describes Human participants; sample size 19; hydrogen delivered as oxyhydrogen. The abstract reports: The physiological and biochemical indexes, including immune inflammation indicators, electrolytes, myocardial enzyme profile, and functions of liver and kidney, were examined and investigated before…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePrenatal Molecular Hydrogen Administration Ameliorates Several Findings in Nitrofen-Induced Congenital Diaphragmatic Hernia.
This animal study examined Prenatal Molecular Hydrogen Administration Ameliorates Several Findings in Nitrofen-Induced Congenital Diaphragmatic Hernia. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: Gasometric results (pH, pO and pCO levels) were better in the CDH + HW group than in the CDH group. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular Hydrogen as a Promising Therapy Could Be Linked With Increased Resting Treg Cells or Decreased Fas+ T Cell Subsets in a IgG4-PF-ILD Patient: A Case Report.
This case report or case series examined Molecular Hydrogen as a Promising Therapy Could Be Linked With Increased Resting Treg Cells or Decreased Fas+ T Cell Subsets in a IgG4-PF-ILD Patient: A Case Report. The abstract describes Human participants. The abstract reports: This case study highlights the effectiveness of hydrogen-assisted therapy in managing PF-ILD complicated by pneumonia, warranting further research in the future. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Attenuates Allergic Inflammation by Reversing Energy Metabolic Pathway Switch.
This uncontrolled human study examined Hydrogen Attenuates Allergic Inflammation by Reversing Energy Metabolic Pathway Switch. The abstract describes Human participants. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular Hydrogen as an Adjuvant Therapy in Comorbid Sjögren’s Syndrome, SLE, and ILD: A Case Report on Immune Modulation and Fatigue Reduction
This case report or case series examined Molecular Hydrogen as an Adjuvant Therapy in Comorbid Sjögren’s Syndrome, SLE, and ILD: A Case Report on Immune Modulation and Fatigue Reduction. The abstract describes Human participants. The abstract reports: This case highlights the potential of molecular hydrogen (H) therapy as a safe, effective adjunct in managing overlapping Sjögren's syndrome, SLE, and ILD. H…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular Hydrogen Positively Affects Physical and Respiratory Function in Acute Post-COVID-19 Patients: A New Perspective in Rehabilitation.
This randomized controlled trial examined Molecular Hydrogen Positively Affects Physical and Respiratory Function in Acute Post-COVID-19 Patients: A New Perspective in Rehabilitation. The abstract describes Human participants; reported duration 14 days. The abstract reports: Results showed that H therapy, compared with placebo, significantly increased 6 MWT distance by 64 ± 39 m, FVC by 0.19 ± 0.24 L,…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of hydrogen inhalation during the warm ischemia phase against lung ischemia-reperfusion injury in rat donors after cardiac death.
This animal study examined Protective effects of hydrogen inhalation during the warm ischemia phase against lung ischemia-reperfusion injury in rat donors after cardiac death. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Lung inhalation with 3% hydrogen during the warm ischemia phase attenuated lung graft IRI via NF-κB-dependent anti-inflammatory and antioxidative effects in rat donors after…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular Hydrogen Modulates the Baroreflex Activity and Reduces the Vascular Adrenoreceptor Sensitivity to Phenylephrine and Lung Inflammation in Rats with Pulmonary Hypertension.
This animal study examined Molecular Hydrogen Modulates the Baroreflex Activity and Reduces the Vascular Adrenoreceptor Sensitivity to Phenylephrine and Lung Inflammation in Rats with Pulmonary Hypertension. The abstract describes Rat model. The abstract reports: No differences in HR response to PE administration were found between any of the experimental groups. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Saline Inhibits Lipopolysaccharide-Induced Acute Lung Injury and Endothelial Dysfunction by Regulating Autophagy through mTOR/TFEB Signaling Pathway.
This animal study examined Hydrogen-Rich Saline Inhibits Lipopolysaccharide-Induced Acute Lung Injury and Endothelial Dysfunction by Regulating Autophagy through mTOR/TFEB Signaling Pathway. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The results confirmed the protection of HRS in LPS-induced ALI by regulating apoptosis through inhibiting the mTOR/TFEB signaling pathway. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen treatment prevents lipopolysaccharide-induced pulmonary endothelial cell dysfunction through RhoA inhibition.
This in vitro or cellular study examined Hydrogen treatment prevents lipopolysaccharide-induced pulmonary endothelial cell dysfunction through RhoA inhibition. The abstract describes Endothelial cell model. The abstract reports: Our findings suggest that RhoA is a crucial protein in the signaling pathway of LPS-induced endothelial cell dysfunction. Hydrogen treatment can prevent LPS-induced junctional…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe Anti-inflammatory Effect of Hydrogen on Lung Transplantation Model of Pulmonary Microvascular Endothelial Cells During Cold Storage Period.
This in vitro or cellular study examined The Anti-inflammatory Effect of Hydrogen on Lung Transplantation Model of Pulmonary Microvascular Endothelial Cells During Cold Storage Period. The abstract describes Endothelial cell model; reported duration 4 hours. The abstract reports: Hydrogen-attenuated inflammatory response in a PMVECs lung transplantation model during cold storage. The effect may be achieved by inhibition of p38 MAPK and NF-κB…. This is an automated editorial draft based on the abstract and requires source review before publication.
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