Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In Caco-2 cells were exposed to different concentrations of LPS (1 μg/mL-1 mg/mL), lPS (100 μg/mL) decreased TER and increased fluorescein-isothiocyanate-dextran flux, which were alleviated by H₂-rich medium. The authors concluded that H₂ improves LPS-induced hyperpermeability of the intestinal barrier and disruptions…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Molecular hydrogen therapy has a protective effect on sepsis, which has been proved by pathological biopsy, level of inflammatory factors/anti-inflammatory…
Read ArticleIn male Sprague-Dawley rats, inhalation of hydrogen (2.5%) markedly reduced the level of serum BUN, CREA and MDA (P < 0.05). These preclinical findings add evidence supporting molecular…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. The present paper overviews the clinical relevance of molecular hydrogen, and summarizes data from clinical trials on this innovative medical…
Read ArticleIn Sprague-Dawley rats, both alcohol dehydrogenase type 1 and acetaldehyde dehydrogenase related with oxidation of alcohol were significantly increased in liver tissue while the level of aspartate aminotransferase…
Read ArticleIn mice, attentively, the difference of H₂ saturation concentration detected in the same tissue was directly proportional to the difference of inhaled exogenous H₂ concentration, namely, the saturation…
Read ArticleIn participants with chronic HD were enrolled and received ERW administration for 6 month, hD resulted in decreased plasma VC, total antioxidant status, and erythrocyte metHb/ferricyanide reductase activity…
Read ArticleIn 1 participants, hydrogen treatment improved cognitive testing scores (P< 0.05), including attention and executive functions. These findings add human evidence supporting molecular hydrogen's therapeutic potential to influence…
Read ArticleHere, the researchers showed that exposure of alfalfa seedlings to paraquat stress increased endogenous H₂ production. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained…
Read ArticleThe authors found significantly reduced NO and H₂ S concentrations in blood samples of COVID-19 patients compared with healthy controls, and free sulfide levels were highly predictive of…
Read ArticleIn rats, hRS reduced oxidative stress and improved myocardial collagen content, which may be related to inhibition of the TGF-β signaling pathway. These preclinical findings add evidence supporting…
Read ArticleIn a laboratory model, mechanistically, released H₂ assists chemotherapeutic drug to efficiently inhibit cancer metastasis by immunoactivating intratumoral M1-phenotype macrophages and consequently downregulating the expression of metastasis-related matrix…
Read ArticleIn a laboratory model, reduced water (RW) such as hydrogen-rich electrolyzed reduced water and natural reduced waters like Hita Tenryosui water in Japan and Nordenau water in Germany…
Read ArticleThis narrative review examined and clarifies the history of hydrogen agronomy and describes recent progress in the field. Hydrogen agronomy focuses mainly on the mechanism of hydrogen gas…
Read ArticleIn 2013 participants, oral and topical hydrogen intervention was found to augment plasma viscosity decrease as compared with the control group (P = 0.04). These findings add human…
Read Article