Quick! Call the authorities! You are under attack! There may be something attacking your joints and tissues and practically every part of your body! What are you going to do about it? I know! Let’s learn about it!
Ok so who has never heard of inflammation? Inflammation is the infamous bad guy that is claimed to cause all of our health problems. And yes, chronic inflammation has been linked to the pathogenesis of many diseases. But inflammation in general gets a bad and potentially undeserved reputation. Now in this video we are going to talk about how H2 can help with inflammation and essentially act as an anti-inflammatory. But first, let’s talk about inflammation in general and what it really is.
Inflammation is the human body’s immune system response to a stimulus. At its core, inflammation is a protective response to protect us from harmful stimuli. Everyone say, “Thank you, inflammation!” The inflammatory response is designed to eliminate the initial cause of cell damage or injury and to get rid of dead cells as well as initiate tissue repair.
Acute inflammation may only exist for a few days or a few weeks. It can have symptoms of redness, heat, swelling, pain, or loss of function.
Now chronic inflammation is your body’s immune system getting confused and attacking healthy tissue or cells. This causes harmful inflammation and leads to having a constant state of inflammation. This can even lead to diseases, such as rheumatoid arthritis, atherosclerosis, psoriasis, Crohn’s disease, and even cancer.
Ok so now let’s get to the fun part. H2 can potentially help with inflammation, but not just 1 way, but 4 ways.
1. Oxidative Stress
The first way that hydrogen can reduce inflammation is by reducing oxidative stress. Oxidative stress can play a pivotal role in the inflammatory process of the human body. Excessive ROS is a known mediator for cell growth, cell death, and the inflammatory response. First H2 effectively reduces oxidative stress in the cells. This leads to less stimulation of a particular pathway that increases inflammation.
2. Down-Regulating Inflammatory Cytokines
The second way hydrogen can reduce inflammation is by down-regulating pro-inflammatory cytokines. Pro-inflammatory cytokines are enzymes in our bodies that work to increase inflammation. H2 can down-regulate these, meaning helps our bodies makes less of these. It can potentially do this in a few ways. Hydrogen can decrease lipid peroxidation and the release of LPS, which decreases the expression of pro-inflammatory cytokines. Hydrogen is also known to upregulate the hormone ghrelin in our gut, which also inhibits pro-inflammatory cytokines. Another way is that hydrogen can influence and regulate the ionic calcium signal transduction pathway, and suppress the NFAT signaling pathway, which both lead to the down-regulation of the expression of pro-inflammatory cytokines. And there may be more ways hydrogen can down-regulate these enzymes that haven’t been discovered yet.
3. Up-Regulating Anti-Inflammatory Cytokines
The third way hydrogen can reduce inflammation is by UP-REGULATING anti-inflammatory cytokines. Yes, you heard that right. Our bodies make these powerful protective enzymes that actually help to fight the inflammation within itself. And even though hydrogen tells our bodies to make LESS of the enzymes that create inflammation. It tells it to make MORE of the ones that fight inflammation. Science is still trying to figure out how hydrogen is doing this. But the data is clear that hydrogen appears to be very effective at this. Just take a look at this study where it says that the levels of the anti-inflammatory cytokines were higher. And later states that hydrogen water’s protective effects were from suppressing the proinflammatory cytokines, and inducing the anti-inflammatory cytokines.
4. Prohibit Elevation of Excessive Inflammation
The fourth way hydrogen to appears to prevent or prohibit the elevation of excessive inflammation in the first place. Hydrogen can inhibit inflammatory cell infiltration and inhibit the production of chemokines. This suppresses a variety of immune and inflammatory responses in various white blood cells. These effects can prevent the elevation of excessive inflammation. And can have a significant potential anti-inflammatory effect on the human body.
So with all that being said, what will you be reaching for to reduce your excessive inflammation? I know what I’m reaching for! Thanks for watching this video and please be sure to subscribe and share! That was your inflammation suppressing dose of H2, in 2 minutes.
This article is the script for the H2Minutes video: Episode 39: Hydrogen Vs. Inflammation (see below).
- https://en.wikipedia.org/wiki/Inflammation
- https://www.ncbi.nlm.nih.gov/books/NBK279298/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257754/
- https://medicalgasresearch.biomedcentral.com/articles/10.1186/2045-9912-3-10
- https://academic.oup.com/ndt/article/25/9/3026/1941444?login=false
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526762/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409143/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731988/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704061/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931094/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525017/