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Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In mice, immunohistochemical staining for the oxidative stress marker, 4-hydroxy-2-nonenal and 8-hydroxydeoxyguanosine, showed that hydrogen administration suppressed oxidative stress induced by ligation in the spinal cord and the dorsal root ganglion. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within…
Read ArticleIn most diseases, the effect of hydrogen has been reported with hydrogen water or hydrogen gas, which was followed by confirmation of the effect with hydrogen-rich saline. These…
Read ArticleIn an animal model, hydrogen improved the deteriorated hypertrophic responses and inhibited the enhanced autophagic activity mediated by ISO administration in vivo, as indicated by decreasing HW and…
Read ArticleIn moderate and severe neonatal HI models, hydrogen gas therapy (2.9% concentration H(2)) was not associated with decreased volume of infarction or decreased concentration of MDA. These preclinical…
Read ArticleIn mice, and, the hydrogen-rich gases pretreatment improved the Hsp60 protein expression in pancreatic tissues of AP mice at 1 h and 5 h. These preclinical findings add…
Read ArticleIn mice, only at the higher doses (4 and 8 mL/kg × 3), HRS conferred favorable histopathological changes in pancreatic tissues, mainly characterized by reduced cytoplasmic vacuole generation,…
Read ArticleIn Sprague-Dawley rats, hydrogen-rich saline treatment significantly attenuated the severity of l-Arg-induced AP by ameliorating the increased serum amylase activity, inhibiting neutrophil infiltration, lipid oxidation and pancreatic tissue…
Read ArticleIn rats, malondialdehyde (MDA) and myeloperoxidase (MPO) contents were obviously reduced, while superoxide dismutase (SOD) and glutathione (GSH) contents were increased after hydrogen-rich saline treatment. These preclinical findings…
Read ArticleIn rats, compared to MNU-treated rats, retinal malondialdehyde (MDA) content in MNU + hydrogen-rich saline rats significantly decreased while superoxide dismutase (SOD) activity significantly increased. These preclinical findings…
Read ArticleIn rats, hRS preserved the retinal function and mitigated the reduction of photoreceptor degeneration in MNU-treated retinas. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within…
Read ArticleHydrogen-rich saline did not obviously ameliorate the signs of uveitis under slit lamp examination and the inflammatory cells infiltration around iris and cilliary body of EIU induced by…
Read ArticleIn conclusion, hydrogen molecule may be neuroprotective against ALS, possibly through abating oxidative and nitrosative stress and preserving mitochondrial function. These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleIn rats, the sphere-forming ability of glioma cells was also suppressed by hydrogen treatment. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and…
Read ArticleIn rats, it was found that systemic HRW treatment slightly suppressed autophagy and then activated the Keap1-Nrf2 signaling pathway by maintaining the Keap1-Nrf2-P62 interaction and improved the osteoporotic…
Read ArticleIn rats, hydrogen-rich saline treatment significantly attenuated lung injury as indicated by significantly improved histological changes in lung, significantly reduced index of quantitative assessment (IQA), MDA content and…
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