APOA2: New Target for Molecular Hydrogen Therapy in Sepsis-Related Lung Injury Based on Proteomic and Genomic Analysis.
This animal study examined APOA2: New Target for Molecular Hydrogen Therapy in Sepsis-Related Lung Injury Based on Proteomic and Genomic Analysis. The abstract describes Mouse model. The abstract reports: Animal experiments helped validate these results. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHigh Concentration Hydrogen Mitigates Sepsis-Induced Acute Lung Injury in Mice by Alleviating Mitochondrial Fission and Dysfunction.
This animal study examined High Concentration Hydrogen Mitigates Sepsis-Induced Acute Lung Injury in Mice by Alleviating Mitochondrial Fission and Dysfunction. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: Lungs are among the organs that are affected in MOF, resulting in acute lung injury. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation attenuates lung contusion after blunt chest trauma in mice.
This animal study examined Hydrogen inhalation attenuates lung contusion after blunt chest trauma in mice. The abstract describes Mouse model; sample size 6; hydrogen delivered as hydrogen inhalation. The abstract reports: Hydrogen inhalation therapy significantly mitigated inflammatory responses associated with lung contusion in mice. Hydrogen inhalation therapy may be a supplemental therapeutic strategy for treating…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHyperbaric oxygen combined with hydrogen-rich saline protects against acute lung injury.
This animal study examined Hyperbaric oxygen combined with hydrogen-rich saline protects against acute lung injury. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: HRS or HBO2 single treatment could decrease inflammatory cytokines release in lung tissue, reduce the accumulation of oxidative products and alleviate apoptosis of pulmonary…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas alleviates lipopolysaccharide-induced acute lung injury and inflammatory response in mice.
This animal study examined Hydrogen gas alleviates lipopolysaccharide-induced acute lung injury and inflammatory response in mice. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: Hydrogen gas alleviates lipopolysaccharide-induced acute lung injury and inflammatory response most probably through the TLR4-NF-κB pathway. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen alleviates asthma through inhibiting IL-33/ILC2 axis
This animal study examined Molecular hydrogen alleviates asthma through inhibiting IL-33/ILC2 axis. The abstract describes Mouse model. The abstract reports: These data demonstrated that H is efficient in suppressing allergen-induced asthma and could be developed as a therapeutics for asthma and other conditions of…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Attenuates Endotoxin-Induced Lung Injury by Activating Thioredoxin 1 and Decreasing Tissue Factor Expression.
This animal study examined Hydrogen Attenuates Endotoxin-Induced Lung Injury by Activating Thioredoxin 1 and Decreasing Tissue Factor Expression. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: LPS-stimulated THP-1 and HUVEC-C cells and showed that hydrogen decreases TF expression and MMP-9 activity, which were abolished by the Trx1 inhibitor, PX12. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe effects of inhaling hydrogen gas on macrophage polarization, fibrosis, and lung function in mice with bleomycin-induced lung injury.
This animal study examined The effects of inhaling hydrogen gas on macrophage polarization, fibrosis, and lung function in mice with bleomycin-induced lung injury. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: The results suggest that hydrogen inhalation inhibits the deterioration of respiratory physiological function and alveolar fibrosis in this model of lung injury. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of a hydrogen-rich solution during cold ischemia in rat lung transplantation.
This animal study examined Protective effects of a hydrogen-rich solution during cold ischemia in rat lung transplantation. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen. The abstract reports: The use of a hydrogen-rich preservation solution attenuates ischemia-reperfusion injury in rat lungs during cold ischemia through antioxidant and anti-inflammatory effects. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMaternal molecular hydrogen treatment attenuates lipopolysaccharide-induced rat fetal lung injury.
This animal study examined Maternal molecular hydrogen treatment attenuates lipopolysaccharide-induced rat fetal lung injury. The abstract describes Rat model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreSaturated hydrogen saline protects the lung against oxygen toxicity.
This animal study examined Saturated hydrogen saline protects the lung against oxygen toxicity. The abstract describes Mouse model; hydrogen delivered as hydrogen water and hydrogen-rich saline. The abstract reports: The light microscope findings showed that saturated hydrogen saline reduced the impairment when compared with the saline group: Saturated hydrogen saline decreased lung edema,…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAttenuation of pulmonary damage in aged lipopolysaccharide-induced inflammation mice through continuous 2 % hydrogen gas inhalation: A potential therapeutic strategy for geriatric inflammation and survival.
This animal study examined Attenuation of pulmonary damage in aged lipopolysaccharide-induced inflammation mice through continuous 2 % hydrogen gas inhalation: A potential therapeutic strategy for geriatric inflammation and survival. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation and hydrogen-rich saline and injected or infused hydrogen. The abstract reports: The study highlights that continuous inhalation of hydrogen gas at a 2 % concentration for 24 h can be a potent intervention in the geriatric population…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreImmersing lungs in hydrogen-rich saline attenuates lung ischaemia-reperfusion injury.
This animal study examined Immersing lungs in hydrogen-rich saline attenuates lung ischaemia-reperfusion injury. The abstract describes Rat model; sample size 3; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Immersing lungs in hydrogen-rich saline delivered hydrogen into the lung and consequently attenuated lung IRI. Hydrogen-rich solution appears to be a promising approach to…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreItraq-Based Quantitative Proteomic Analysis of Lungs in Murine Polymicrobial Sepsis with Hydrogen Gas Treatment.
This uncontrolled human study examined Itraq-Based Quantitative Proteomic Analysis of Lungs in Murine Polymicrobial Sepsis with Hydrogen Gas Treatment. The abstract describes Human participants. The abstract reports: Functional enrichment analysis showed that H2-related differential proteins could be related to muscle contraction, oxygen transport, protein synthesis, collagen barrier membranes, cell adhesion, and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation reduced epithelial apoptosis in ventilator-induced lung injury via a mechanism involving nuclear factor-kappa B activation.
This animal study examined Hydrogen inhalation reduced epithelial apoptosis in ventilator-induced lung injury via a mechanism involving nuclear factor-kappa B activation. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: We recently demonstrated the inhalation of hydrogen gas, a novel medical therapeutic gas, ameliorates ventilator-induced lung injury (VILI); however, the molecular mechanisms by which…. This is an automated editorial draft based on the abstract and requires source review before publication.
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