Effect of molecular hydrogen treatment on Sepsis-Associated encephalopathy in mice based on gut microbiota.
This uncontrolled human study examined Effect of molecular hydrogen treatment on Sepsis-Associated encephalopathy in mice based on gut microbiota. The abstract describes Human participants; hydrogen delivered as hydrogen water and hydrogen inhalation. The abstract reports: Molecular hydrogen treatment promotes functional outcomes after SAE in mice, which may be attributable to increasing beneficial bacteria, repressing harmful bacteria, and metabolic disorder,…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreiTRAQ-Based Quantitative Proteomic Analysis of Intestines in Murine Polymicrobial Sepsis with Hydrogen Gas Treatment.
This uncontrolled human study examined iTRAQ-Based Quantitative Proteomic Analysis of Intestines in Murine Polymicrobial Sepsis with Hydrogen Gas Treatment. The abstract describes Human participants. The abstract reports: A total of 199 differential proteins were related with H in the intestinal protection of sepsis. H-related differential proteins were notably enriched in the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHigh-concentration hydrogen inhalation mitigates sepsis-associated encephalopathy in mice by improving mitochondrial dynamics.
This animal study examined High-concentration hydrogen inhalation mitigates sepsis-associated encephalopathy in mice by improving mitochondrial dynamics. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: Inhalation of high concentration (67%) of H in septic mice improved the survival rate and reduced neuronal injury. Its mechanism might be mediated by…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePharmacokinetics of hydrogen administered intraperitoneally as hydrogen-rich saline and its effect on ischemic neuronal cell death in the brain in gerbils.
This in vitro or cellular study examined Pharmacokinetics of hydrogen administered intraperitoneally as hydrogen-rich saline and its effect on ischemic neuronal cell death in the brain in gerbils. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Intraperitoneal administration of H2-rich saline resulted in large increases in H2 concentration in the IVC ranging from 0.00183 mg/L (0.114%) to 0.00725 mg/L (0.453%). This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen‐rich and hyperoxygenate saline inhibits lipopolysaccharide‐induced lung injury through mediating NF‐κB/NLRP3 signaling pathway in C57BL/6 mice
This animal study examined Hydrogen‐rich and hyperoxygenate saline inhibits lipopolysaccharide‐induced lung injury through mediating NF‐κB/NLRP3 signaling pathway in C57BL/6 mice. The abstract describes Mouse model; hydrogen delivered as injected or infused hydrogen. The abstract reports: Hydrogen plays a more important role in the inflammatory and anti-apoptosis mechanisms, while oxygen improves hypoxia of the body, and thus, its molecular mechanism…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreSafety of inhaled hydrogen gas in healthy mice.
This animal study examined Safety of inhaled hydrogen gas in healthy mice. The abstract describes Mouse model; sample size 25; hydrogen delivered as hydrogen inhalation; reported duration 72 hours. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective Effects of Hydrogen against Low‐Dose Long‐Term Radiation‐Induced Damage to the Behavioral Performances, Hematopoietic System, Genital System, and Splenic Lymphocytes in Mice
This animal study examined Protective Effects of Hydrogen against Low‐Dose Long‐Term Radiation‐Induced Damage to the Behavioral Performances, Hematopoietic System, Genital System, and Splenic Lymphocytes in Mice. The abstract describes Mouse model. The abstract reports: And significant differences between the treatment group and the radiation-only groups were observed, showing that H could diminish the detriment induced by LDLTR and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePharmacokinetics of a single inhalation of hydrogen gas in pigs.
This animal study examined Pharmacokinetics of a single inhalation of hydrogen gas in pigs. The abstract describes Animal model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreBiological safety of neutral-pH hydrogen-enriched electrolyzed water upon mutagenicity, genotoxicity and subchronic oral toxicity
This animal study examined Biological safety of neutral-pH hydrogen-enriched electrolyzed water upon mutagenicity, genotoxicity and subchronic oral toxicity. The abstract describes Rat model; reported duration 28 days. The abstract reports: Hydrogen-dissolved water has been suggested to be effective for alleviating the oxidative stress. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline reduces airway remodeling via inactivation of NF-κB in a murine model of asthma.
This animal study examined Hydrogen-rich saline reduces airway remodeling via inactivation of NF-κB in a murine model of asthma. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: These findings suggest that hydrogen-rich saline reduces airway inflammation and remodeling in OVA-exposed mice by inhibiting NF-κB. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePharmacokinetics of Hydrogen During Hydrogen-Saturated Saline Infusion in Pigs.
This animal study examined Pharmacokinetics of Hydrogen During Hydrogen-Saturated Saline Infusion in Pigs. The abstract describes Animal model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation: in vivo rat genotoxicity tests.
This animal study examined Hydrogen inhalation: in vivo rat genotoxicity tests. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePharmacokinetics of hydrogen after ingesting a hydrogen-rich solution: A study in pigs.
This animal study examined Pharmacokinetics of hydrogen after ingesting a hydrogen-rich solution: A study in pigs. The abstract describes Animal model; hydrogen delivered as hydrogen water and injected or infused hydrogen; reported duration 120 min. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective Effects of a Hydrogen-Rich Preservation Solution in a Canine Lung Transplantation Model.
This animal study examined Protective Effects of a Hydrogen-Rich Preservation Solution in a Canine Lung Transplantation Model. The abstract describes Canine model; reported duration 4 hours. The abstract reports: Our results demonstrated that the H-rich preservation solution attenuated ischemia-reperfusion injury in a canine left LTx model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular Hydrogen Ameliorates Anti-Desmoglein 1 Antibody-Induced Pemphigus-Associated Interstitial Lung Disease by Inhibiting Oxidative Stress.
This uncontrolled human study examined Molecular Hydrogen Ameliorates Anti-Desmoglein 1 Antibody-Induced Pemphigus-Associated Interstitial Lung Disease by Inhibiting Oxidative Stress. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: Using a BALB/cJGpt mouse model, we demonstrated that anti-Dsg 1 antibodies, but not anti-Dsg 3 antibodies, induced interstitial inflammation and fibrosis. This is an automated editorial draft based on the abstract and requires source review before publication.
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