Hydrogen-rich saline attenuates spinal cord hemisection-induced testicular injury in rats.
This animal study examined Hydrogen-rich saline attenuates spinal cord hemisection-induced testicular injury in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The results indicated that hSCI significantly decreased the hind limb neurological function, testis index, MSTD, and MSET, and induced severe testicular morphological injury. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen exerts neuroprotective effects by inhibiting oxidative stress in experimental diabetic peripheral neuropathy rats.
This animal study examined Hydrogen exerts neuroprotective effects by inhibiting oxidative stress in experimental diabetic peripheral neuropathy rats. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation and hydrogen-rich saline. The abstract reports: Further studies showed that hydrogen significantly upregulated the expression of nuclear factor erythroid-2-related factor 2 and downstream proteins such as catalase and hemeoxygenase-1 in…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen alleviates hypoxic-ischaemic brain damage in neonatal rats by inhibiting injury of brain pericytes.
This animal study examined Hydrogen alleviates hypoxic-ischaemic brain damage in neonatal rats by inhibiting injury of brain pericytes. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: The results showed that HRW significantly attenuated HI-induced oxidative stress in the brain pericytes of neonatal rats, partly through the Nrf2-HO-1 pathway, further improving…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Promotes the Effectiveness of Bone Mesenchymal Stem Cell Transplantation in Rats with Spinal Cord Injury.
This animal study examined Hydrogen Promotes the Effectiveness of Bone Mesenchymal Stem Cell Transplantation in Rats with Spinal Cord Injury. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Gas Attenuates Hypoxic-Ischemic Brain Injury via Regulation of the MAPK/HO-1/PGC-1a Pathway in Neonatal Rats.
This animal study examined Hydrogen Gas Attenuates Hypoxic-Ischemic Brain Injury via Regulation of the MAPK/HO-1/PGC-1a Pathway in Neonatal Rats. The abstract describes Rat model. The abstract reports: These findings suggest that H augments cellular antioxidant defense capacity through activation of MAPK signaling pathways, leading to HO-1 expression and subsequent upregulation of…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation protects hypoxic-ischemic brain damage by attenuating inflammation and apoptosis in neonatal rats.
This animal study examined Hydrogen inhalation protects hypoxic-ischemic brain damage by attenuating inflammation and apoptosis in neonatal rats. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: The results showed that hypoxia–ischemia injury induced the inflammatory response of microglia; however, these changes were inhibited by hydrogen inhalation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of hydrogen‑rich saline against experimental diabetic peripheral neuropathy via activation of the mitochondrial ATP‑sensitive potassium channel channels in rats.
This animal study examined Protective effects of hydrogen‑rich saline against experimental diabetic peripheral neuropathy via activation of the mitochondrial ATP‑sensitive potassium channel channels in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: It has previously been demonstrated that hyperglycemia‑induced oxidative stress and inflammation are closely associated with the development of diabetic complications, including diabetic neuropathy. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of hydrogen-rich saline in neuroinflammation and mitochondrial dysfunction in rat model of sepsis-associated encephalopathy.
This uncontrolled human study examined Effects of hydrogen-rich saline in neuroinflammation and mitochondrial dysfunction in rat model of sepsis-associated encephalopathy. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: These data demonstrated that HRS can improve survival rate, attenuate neuroinflammation, astrocyte and microglial activation, neuronal injury and mitochondrial dysfunction in juvenile SAE rat…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreNeuroprotective potential of molecular hydrogen against perinatal brain injury via suppression of activated microglia.
This animal study examined Neuroprotective potential of molecular hydrogen against perinatal brain injury via suppression of activated microglia. The abstract describes Mouse model; hydrogen delivered as hydrogen water and injected or infused hydrogen. The abstract reports: These results suggested that H2 holds promise for the prevention of inflammation related to perinatal brain injury. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePPARα contributes to the therapeutic effect of hydrogen gas against sepsis-associated encephalopathy with the regulation to the CREB-BDNF signaling pathway and hippocampal neuron plasticity-related gene expression.
This animal study examined PPARα contributes to the therapeutic effect of hydrogen gas against sepsis-associated encephalopathy with the regulation to the CREB-BDNF signaling pathway and hippocampal neuron plasticity-related gene expression. The abstract describes Mouse model. The abstract reports: The results showed the expression of PPARα was decreased in SAE mice and that activation of PPARα in septic mice improved the survival rate…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreImpact of hydrogen gas inhalation during therapeutic hypothermia on cerebral hemodynamics and oxygenation in the asphyxiated piglet.
This animal study examined Impact of hydrogen gas inhalation during therapeutic hypothermia on cerebral hemodynamics and oxygenation in the asphyxiated piglet. The abstract describes Porcine model; hydrogen delivered as hydrogen inhalation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMaternal molecular hydrogen administration on lipopolysaccharide-induced mouse fetal brain injury.
This animal study examined Maternal molecular hydrogen administration on lipopolysaccharide-induced mouse fetal brain injury. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: Our results suggest that LPS-induced apoptosis, oxidative damage and inflammation in the fetal brain were ameliorated by maternal H2 administration. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline reduces delayed neurologic sequelae in experimental carbon monoxide toxicity.
This uncontrolled human study examined Hydrogen-rich saline reduces delayed neurologic sequelae in experimental carbon monoxide toxicity. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 40 min. The abstract reports: This observation demonstrated that hydrogen-rich saline peritoneal injection improves histologic and functional assessment in a rat model of CO encephalopathy. Hydrogen saline has potentials…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePerioperatively Inhaled Hydrogen Gas Diminishes Neurologic Injury Following Experimental Circulatory Arrest in Swine.
This animal study examined Perioperatively Inhaled Hydrogen Gas Diminishes Neurologic Injury Following Experimental Circulatory Arrest in Swine. The abstract describes Porcine model; hydrogen delivered as hydrogen inhalation. The abstract reports: This study used a swine model of mildly hypothermic prolonged circulatory arrest and found that the addition of 2.4% inhaled hydrogen gas to inspiratory…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe neuroprotective effect of hyperoxygenate hydrogen-rich saline on CO-induced brain injury in rats.
This animal study examined The neuroprotective effect of hyperoxygenate hydrogen-rich saline on CO-induced brain injury in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Arterial oxygen partial pressure (PaO) and arterial oxygen saturation (SaO) results showed that HOS and HOHS could improve the oxygenation of the rats with…. This is an automated editorial draft based on the abstract and requires source review before publication.
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