Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In male Sprague-Dawley rats, hydrogen gas significantly alleviated brain edema and blood-brain barrier disruption, reduced apoptosis, and improved neurologic function at 24 hrs but not 72 hrs after subarachnoid hemorrhage. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the…
Read ArticleIn an animal model, after the CPR, blood pH, base excess, and lactate showed significantly smaller deterioration in the hydrogen group than in the control group. These preclinical…
Read ArticleIn mice, hS significantly improved neurological function, reduced infarct volume, and increased cerebral blood flow in a dMCAO mouse model. These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleIn mice, the outcomes illustrated that hydrogen-rich saline treatment considerably enhanced the neurological score, increased neuronal survival, decreased the levels of serum MDA and brain ROS, increased the…
Read ArticleThe results show that hydrogen-rich saline treatment markedly increased the survival rate and neurological score, increased neuron survival, downregulated the autophagy protein expression of Beclin-1 and LC3, and…
Read ArticleIn conclusion, this is the first study to use MRI to longitudinally study H₂ and H2M treatment on ischemic stroke and the first study to compare H₂ treatment…
Read ArticleIn rats, during the 1 hour observation time at 48 hours post-resuscitation, seizures were observed in 50% of ACA and 20% of ACA + H₂ pre- & post-treatment…
Read ArticleIn Sprague-Dawley rats, hS treatment attenuated increases in apoptosis and autophagy postburn in wounds, according to the TUNEL staining results and the expression analysis of Bax, Bcl-2, caspase-3,…
Read ArticleIn male Sprague-Dawley rats, hydrogen-rich saline ameliorated inflammatory infiltration and decreased cellular apoptosis. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological…
Read ArticleIn rats, hRS treatment also reduced inflammatory cell infiltration induced by I/R injury. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological…
Read ArticleIn male Sprague Dawley rats, preconditioning with one-time inhaled hydrogen does not attenuate skin flap IR injuries in rat models. These preclinical findings add evidence about the molecular-hydrogen…
Read ArticleIn rats, the mRNA expression of iNOS in rats with hydrogen-rich water intake was lower than that in the control group at both 3 and 7 days after…
Read ArticleIn mice, hydrogen water (HW) produced by electrolysis of water has characteristics of extremely low oxidation-reduction potential (ORP) value and high dissolved hydrogen (DH). These preclinical findings add…
Read ArticleIn mice, the levels of Th2 cytokine, interleukin-5 (IL-5), and proinflammatory cytokines such as tumor necrosis factor-α and IL-6 in HW-fed mice were significantly lower than in control…
Read ArticleIn mice, hydrogen water treatment decreased serum TARC levels from 73.3±27.9 pg/mL at baseline to 53.2±18.3 pg/mL at week 4 ( p =0.0107); however, no differences were detected…
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