Molecular hydrogen alleviates motor deficits and muscle degeneration in mdx mice.

This uncontrolled human study examined Molecular hydrogen alleviates motor deficits and muscle degeneration in mdx mice. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: Hydrogen water prevented abnormal body mass gain that is commonly observed in mdx mice. Hydrogen improved the spontaneous running distance that was estimated by…. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Hydrogen therapy may be an effective and specific novel treatment for acute graft-versus-host disease (GVHD).

This animal study examined Hydrogen therapy may be an effective and specific novel treatment for acute graft-versus-host disease (GVHD). The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: Besides, the oxidation phenomena and/or the formation of free radicals have been suggested to be causally related to various haematological disorders including aGVHD. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Effects of three hydrogen-rich liquids on hemorrhagic shock in rats.

This animal study examined Effects of three hydrogen-rich liquids on hemorrhagic shock in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Each hydrogen-rich liquid resuscitation preparation could protect the lung against acute injury secondary to UHS. These mechanisms may be associated with hydrogen inhibiting the release of…. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Inhalation of Molecular Hydrogen, a Rescue Treatment for Noise-Induced Hearing Loss.

This uncontrolled human study examined Inhalation of Molecular Hydrogen, a Rescue Treatment for Noise-Induced Hearing Loss. The abstract describes Human participants. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Molecular hydrogen as an energy source for Helicobacter pylori.

This animal study examined Molecular hydrogen as an energy source for Helicobacter pylori. The abstract describes Mouse model. The abstract reports: We found that hydrogen is available in the gastric mucosa of mice and that its use greatly increased the stomach colonization by H. pylori. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Prenatal Molecular Hydrogen Administration Ameliorates Several Findings in Nitrofen-Induced Congenital Diaphragmatic Hernia.

This animal study examined Prenatal Molecular Hydrogen Administration Ameliorates Several Findings in Nitrofen-Induced Congenital Diaphragmatic Hernia. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: Gasometric results (pH, pO and pCO levels) were better in the CDH + HW group than in the CDH group. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

An LCMS-based untargeted metabolomics protocol for cochlear perilymph: highlighting metabolic effects of hydrogen gas on the inner ear of noise exposed Guinea pigs.

This animal study examined An LCMS-based untargeted metabolomics protocol for cochlear perilymph: highlighting metabolic effects of hydrogen gas on the inner ear of noise exposed Guinea pigs. The abstract describes Animal model. The abstract reports: A HILIC-UHPLC-Q-TOF-MS-based protocol for untargeted metabolomics of perilymph is presented and shown to be fit-for-purpose. We found a clear difference in the perilymph metabolome…. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Taurine, Coenzyme Q10, and Hydrogen Water Prevents Germanium Dioxide-Induced Mitochondrial Dysfunction and Associated Sensorineural Hearing Loss in mouse

This animal study examined Taurine, Coenzyme Q10, and Hydrogen Water Prevents Germanium Dioxide-Induced Mitochondrial Dysfunction and Associated Sensorineural Hearing Loss in mouse. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: In the current study, we showed that supplementation with germanium dioxide (GeO) in CBA/J mice resulted in SNHL due to the degeneration of the…. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

A link between gut community metabolism and pathogenesis: molecular hydrogen-stimulated glucarate catabolism aids Salmonella virulence.

This animal study examined A link between gut community metabolism and pathogenesis: molecular hydrogen-stimulated glucarate catabolism aids Salmonella virulence. The abstract describes Mouse model. The abstract reports: Our results link a gut microbiome-produced diffusible metabolite to augmenting bacterial pathogenesis. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Molecular hydrogen stimulates the gene expression of transcriptional coactivator PGC-1α to enhance fatty acid metabolism.

This animal study examined Molecular hydrogen stimulates the gene expression of transcriptional coactivator PGC-1α to enhance fatty acid metabolism. The abstract describes Mouse model. The abstract reports: The expression of might be regulated indirectly through sequential regulation by H, 4-hydroxy-2-nonenal, and Akt/FoxO1 signaling, as suggested in cultured cell experiments. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Hydrogen-rich saline attenuates neuronal ischemia–reperfusion injury by protecting mitochondrial function in rats.

This animal study examined Hydrogen-rich saline attenuates neuronal ischemia–reperfusion injury by protecting mitochondrial function in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Hydrogen, a popular antioxidant gas, can selectively reduce cytotoxic oxygen radicals and has been found to protect against ischemia-reperfusion (I/R) injury of multiple organs. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Hydrogen-rich saline protects against mitochondrial dysfunction and apoptosis in mice with obstructive jaundice.

This animal study examined Hydrogen-rich saline protects against mitochondrial dysfunction and apoptosis in mice with obstructive jaundice. The abstract describes Mouse model; sample size 6; hydrogen delivered as hydrogen-rich saline. The abstract reports: Previous studies have demonstrated that hydrogen-rich saline (HS) protects against bile duct ligation (BDL)-induced liver injury by suppressing oxidative stress and inflammation. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Molecular hydrogen modulates gene expression via histone modification and induces the mitochondrial unfolded protein response.

This animal study examined Molecular hydrogen modulates gene expression via histone modification and induces the mitochondrial unfolded protein response. The abstract describes Mouse model. The abstract reports: We found that H activated the expression of sets of genes regulated by histone H3K27 methylation status. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Hydrogen restores central tryptophan and metabolite levels and maintains mitochondrial homeostasis to protect rats from chronic mild unpredictable stress damage.

This animal study examined Hydrogen restores central tryptophan and metabolite levels and maintains mitochondrial homeostasis to protect rats from chronic mild unpredictable stress damage. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: The results collectively indicated that hydrogen significantly attenuated CUMS-induced depressive-like behavior and monoamine neurotransmitter deficiency, as well as protected the brain from oxidative stress…. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Hydrogen-rich water supplementation improves metabolic profile during peripartum period in Gurcu goats and enhances the health and survival of kids.

This animal study examined Hydrogen-rich water supplementation improves metabolic profile during peripartum period in Gurcu goats and enhances the health and survival of kids. The abstract describes hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More