Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In an animal model, consistently, hydrogen decreased proliferative marker expression, including BCL2, BAX, and Ki-67, and significantly reduced ROS and inflammatory cytokines production. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this…
Read ArticleIn mice, HRW significantly reduced plasma triglyceride and total cholesterol levels, increased high-density lipoprotein cholesterol levels, and alleviated skin lesions in mice. These preclinical findings add evidence supporting…
Read ArticleIn mice, by naked eye, the severity of skin lesions in hydrogen-rich water bath group was lower than that in distilled water bath group, and the psoriasis severity…
Read ArticleIn mice, local treatment of hydrogen-rich water shortened wound closure time and reduced the level of proinflammatory cytokines and lipid peroxidation. These preclinical findings add evidence supporting molecular…
Read ArticleIn rats, the Si-based agent was found to effectively suppress I/R injury in skin flaps, and allow for the production of a large amount of hydrogen continuously via…
Read ArticleIn rats, prophylactic instillation of hydrogen suppressed alkali burn-induced oxidative stress of the cornea and promoted wound healing. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential…
Read ArticleIn dogs, HRW treatment promoted skin wound healing in dogs, accelerated wound epithelization, reduced inflammatory reaction, stimulated the expression of cytokines related to wound healing, and shortened wound…
Read ArticleIn Sprague-Dawley rats, repeated HRS injections after trauma increased the viability of skin flap in rat degloving injury model by decreasing local tissue injury, due to its antioxidant,…
Read ArticleIn male Sprague-Dawley rats, rIP1, RIP3, MLKL, PGAM5 and Drp1 were expressed at high levels in the IR group, and their expression was significantly decreased in the HCH…
Read ArticleIn mice, hydrogen treatment upregulated SIRT1 expression and promoted PINK1/Parkin-mediated mitophagy, leading to reduced phosphorylation of STING, decreased levels of pro-inflammatory cytokines (IL-1β, IL-6, and TNF-α), and suppressed…
Read ArticleIn an animal model, the incidence of bacterial translocation at 24 h after CLP as assessed by cultivation of mesenteric lymph nodes and blood was significantly decreased in…
Read ArticleIn mice, therapy with 2% H₂ increased the survival rate, alleviated the injuries caused by oxidative stress and inflammation, reduced HMGB1 levels but increased HO-1 levels in WT…
Read ArticleIn vitro assays showed that burn serum reduced fibroblast proliferation and increased apoptosis (P < 0.01), which hydrogen gas mitigated by rescuing cell viability and reducing apoptosis (P…
Read ArticleIn mice, molecular hydrogen treatment improved gut microbiota dysbiosis and partially amended metabolic disorder after SAE. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the…
Read ArticleIn mice, the load of blood and peritoneal lavage bacteria was increased, and H₂ treatment can significantly reduce it. These preclinical findings add evidence supporting molecular hydrogen's therapeutic…
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