Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In mice, intermittent hypoxia significantly increased plasma levels of low- and very low-density cholesterol and the amount of 4-hydroxy-2-nonenal-modified protein adducts in the LV myocardium. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured…
Read ArticleIn male Wistar rats, during mild SI, H₂ reduced plasma surges of proinflammatory cytokines (TNF-α and IL-6) while caused an increase in plasma IL-10 (anti-inflammatory cytokine) and prevented…
Read ArticleIn mice, HRW-treated mice exhibit improved serum lipid profiles, including decreased levels of low-density lipoprotein (LDL), triglycerides (TG), and total cholesterol (T-CHO), as well as reduced lipid accumulation.…
Read ArticleIn mice, compared with WT-H₂ mice, 5xFAD-Veh mice exhibited increased BAX expression ( p < 0.05) and reduced BCL-2 expression, whereas H₂ treatment in 5xFAD-H₂ mice decreased BAX,…
Read ArticleIn mice, this study showed that administration of H₂-rich saline by peritoneal injection (6 mL/kg/24 h) improved the cognitive deficits and reduced the degree of necrosis, apoptosis, and…
Read ArticleIn male Wistar rats, hW intake may prevent lipid deposition in the rat aorta induced by periodontitis by decreasing serum ox-LDL levels and aortic oxidative stress. These preclinical…
Read ArticleIn female Sprague-Dawley rats, saturated hydrogen saline could protect the retina from light-induced damage by attenuating oxidative stress. These results are preclinical and suggest molecular hydrogen's therapeutic potential…
Read ArticleIn mice, hydrogen-rich water improved brain energy metabolism disorders and intestinal flora imbalances and reduced inflammatory reactions. These results are preclinical and suggest molecular hydrogen's therapeutic potential in…
Read ArticleIn Sprague-Dawley rats, hydrogen-rich saline treatment significantly improved the amount of surviving cells (P < 0.05). These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the…
Read ArticleIn rats, neuronal degeneration and microglial activation in a vulnerable brain region was suppressed by both TTM alone and H₂ inhalation alone, with the combined therapy of TTM…
Read ArticleIn rats, maximum intracavernous pressure in diabetic rats decreased significantly compared to controls and increased significantly compared to untreated diabetic rats after hydrogen-rich saline treatment. These results are…
Read ArticleIn rats, compared with Group B, the mean activities of the antioxidant enzymes superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase, and glutathione S-transferase, levels of GSH, and total…
Read ArticleIn an animal model, hW treatment significantly reduced ethylene production and respiratory rate, and inhibited the expressions of ethylene synthesis- and signaling-related genes. These preclinical findings add evidence…
Read ArticleHydrogen-rich saline did not obviously ameliorate the signs of uveitis under slit lamp examination and the inflammatory cells infiltration around iris and cilliary body of EIU induced by…
Read ArticleIn mice, spinal cord neurons were preserved by hydrogen administration after mechanical injury in a dose-dependent manner. These results are preclinical and suggest molecular hydrogen's therapeutic potential in…
Read Article