Hydrogen inhibits endometrial cancer growth via a ROS/NLRP3/caspase-1/GSDMD-mediated pyroptotic pathway
This animal study examined Hydrogen inhibits endometrial cancer growth via a ROS/NLRP3/caspase-1/GSDMD-mediated pyroptotic pathway. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: This study extended our original analysis of the ability of hydrogen to stimulate NLRP3 inflammasome/GSDMD activation in pyroptosis and revealed possible mechanism (s) for…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas improves left ventricular hypertrophy in Dahl rat of salt-sensitive hypertension
This animal study examined Hydrogen gas improves left ventricular hypertrophy in Dahl rat of salt-sensitive hypertension. The abstract describes Rat model. The abstract reports: Our findings suggest that chronic H gas inhalation may help prevent LV hypertrophy in hypertensive DS rats. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtection of oral hydrogen water as an antioxidant on pulmonary hypertension
This animal study examined Protection of oral hydrogen water as an antioxidant on pulmonary hypertension. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: The results showed that the mean pulmonary arterial pressure, right ventricle weight and right ventricular hypertrophy index in MCT group were significant higher than…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe Role of Mast Cells in the Remodeling Effects of Molecular Hydrogen on the Lung Local Tissue Microenvironment under Simulated Pulmonary Hypertension.
This animal study examined The Role of Mast Cells in the Remodeling Effects of Molecular Hydrogen on the Lung Local Tissue Microenvironment under Simulated Pulmonary Hypertension. The abstract describes Rat model. The abstract reports: MPH resulted in a significantly increased number of MCs in both the pneumatic and respiratory parts of the lungs, an increased number of tryptase-positive…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas reduces chronic intermittent hypoxia‐induced hypertension by inhibiting sympathetic nerve activity and increasing vasodilator responses via the antioxidation
This animal study examined Hydrogen gas reduces chronic intermittent hypoxia‐induced hypertension by inhibiting sympathetic nerve activity and increasing vasodilator responses via the antioxidation. The abstract describes Rat model; reported duration 5 weeks. The abstract reports: We found that the systolic and diastolic blood pressure (BP) increased significantly in rats exposed to intermittent hypoxia, both of which were markedly attenuated…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of hydrogen-rich water and ascorbic acid treatment on spontaneously hypertensive rats.
This animal study examined Effects of hydrogen-rich water and ascorbic acid treatment on spontaneously hypertensive rats. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: Hydrogen-rich water (HW) has been suggested to possess antioxidant properties of value in treatments of lifestyle diseases and for prevention of latent pathologies. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of hydrogen-rich saline on monocrotaline-induced pulmonary hypertension in a rat model.
This animal study examined Protective effects of hydrogen-rich saline on monocrotaline-induced pulmonary hypertension in a rat model. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: These results suggest that hydrogen-rich saline ameliorates the progression of pulmonary hypertension induced by monocrotaline in rats, which may be associated with its antioxidant…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreConsumption of hydrogen-rich water alleviates renal injury in spontaneous hypertensive rats.
This uncontrolled human study examined Consumption of hydrogen-rich water alleviates renal injury in spontaneous hypertensive rats. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: Recently, it has been demonstrated that hydrogen, as a novel antioxidant, can selectively reduce hydroxyl radicals and peroxynitrite anion to exert therapeutic antioxidant activity. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen ameliorates pulmonary hypertension in rats by anti-inflammatory and antioxidant effects.
This animal study examined Hydrogen ameliorates pulmonary hypertension in rats by anti-inflammatory and antioxidant effects. The abstract describes Rat model. The abstract reports: Molecular hydrogen ameliorates MCT-induced PAH in rats by suppressing macrophage accumulation, reducing oxidative stress and modulating the STAT3/NFAT axis. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Inhalation Reduces Lung Inflammation and Blood Pressure in the Experimental Model of Pulmonary Hypertension in Rats.
This animal study examined Hydrogen Inhalation Reduces Lung Inflammation and Blood Pressure in the Experimental Model of Pulmonary Hypertension in Rats. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: The results showed that, although hydrogen inhalation had no effect on the main markers of pulmonary hypertension induced by monocrotaline injection, there was a…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreDaily inhalation of hydrogen gas has a blood pressure-lowering effect in a rat model of hypertension
This animal study examined Daily inhalation of hydrogen gas has a blood pressure-lowering effect in a rat model of hypertension. The abstract describes Rat model. The abstract reports: A recent clinical study demonstrated that haemodialysis with a dialysate containing hydrogen (H) improves blood pressure control in end-stage kidney disease. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Saline Attenuates Chronic Allodynia after Bone Fractures via Reducing Spinal CXCL1/CXCR2-Mediated Iron Accumulation in Mice.
This animal study examined Hydrogen-Rich Saline Attenuates Chronic Allodynia after Bone Fractures via Reducing Spinal CXCL1/CXCR2-Mediated Iron Accumulation in Mice. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: These findings identify that hydrogen-rich saline confers protection against fracture-caused chronic allodynia via spinal down-modulation of CXCL1-dependent TfR1-mediated iron accumulation in mice. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular Hydrogen Prevents Osteoclast Activation in a Glucocorticoid-Induced Osteoporosis Zebrafish Scale Model.
This animal study examined Molecular Hydrogen Prevents Osteoclast Activation in a Glucocorticoid-Induced Osteoporosis Zebrafish Scale Model. The abstract describes Zebrafish model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffect of H 2 treatment in a mouse model of rheumatoid arthritis‐associated interstitial lung disease
This uncontrolled human study examined Effect of H 2 treatment in a mouse model of rheumatoid arthritis‐associated interstitial lung disease. The abstract describes Human participants. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen (H) Alleviates Osteoarthritis by Inhibiting Apoptosis and Inflammation via the JNK Signaling Pathway.
This animal study examined Hydrogen (H) Alleviates Osteoarthritis by Inhibiting Apoptosis and Inflammation via the JNK Signaling Pathway. The abstract describes Mouse model. The abstract reports: We uncovered that hydrogen (H) could alleviate apoptosis response and ECM degradation in human chondrocytes via inhibiting the activation of the JNK signaling pathway.…. This is an automated editorial draft based on the abstract and requires source review before publication.
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