Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In mice, H₂ mice showed significantly higher retinal thickness as compared to controls on optical coherence tomography. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.
Read ArticleThe researchers found that hydrogen decreased the expression of the DNA damage-related protein ATM, cyclinD1 and NF-κB but increased the expression of the DNA repair-related protein HMGB1, suggesting…
Read ArticleThe findings demonstrate that inhalation of hydrogen gas could alleviate retinal oedema, shorten reopen time and improve retinal function, and the potential mechanism might be related to a…
Read ArticleIn guinea pigs, compared with the glutamate-induced injury group, the hydrogen-rich saline treatment reduced the loss of cells in the GCL and thinning of the retina and attenuated…
Read ArticleIn rats, s-nitroso-N-acetylpenicillamine treatment decreased the cell numbers in the ganglion cell layer and inner nuclear layer, but the presence of H₂ inhibited this reduction. These preclinical findings…
Read ArticleIn rats, fIGURE 4 Hydrogen rich saline induced effects on the oxygen stress markers of MNU administered rats. (A) The SOD level of the untreated group was significantly…
Read ArticleIn male Sprague-Dawley rats, molecular hydrogen (H₂) has been widely reported to have benefiicial effects in diverse animal models and human disease through reduction of oxidative stress and…
Read ArticleIn female Sprague-Dawley rats, saturated hydrogen saline could protect the retina from light-induced damage by attenuating oxidative stress. These results are preclinical and suggest molecular hydrogen's therapeutic potential…
Read ArticleIn rats, h&E, gamma synuclein staining and CTB tracing showed that the survival rate of RGCs in hydrogen saline-treated group was significantly higher than that in saline-treated group.…
Read ArticleIn male Sprague-Dawley rats, these results indicated that peritoneal injection of HRS provides protection and treatment against light-induced retinal degeneration in rats. These preclinical findings add evidence supporting…
Read ArticleIn rats, compared with Group B, the mean activities of the antioxidant enzymes superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase, and glutathione S-transferase, levels of GSH, and total…
Read ArticleThe results demonstrated that HRS administration improved morphological alterations and reduced apoptosis following RIR injury. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes…
Read ArticleIn mice, at P14 and P21, no significant difference in the distance from the retinal pigment epithelium to the outer plexiform layer on OCT from mice of the…
Read ArticleThe researchers tested the hypothesis that H₂ decreases intense acute exercise-induced inflammation in the hippocampus, since it is a brain region particularly susceptible to inflammation. These preclinical findings…
Read ArticleIn mice, positive metabolic effects in HW group were revealed by the significant reduction of blood glucose, lactate, and BUN in serum after 4 wk (p < 0.01,…
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