Hydrogen Gas Attenuates Toxic Metabolites and Oxidative Stress-Mediated Signaling to Inhibit Neurodegeneration and Enhance Memory in Alzheimer’s Disease Models.

This animal study examined Hydrogen Gas Attenuates Toxic Metabolites and Oxidative Stress-Mediated Signaling to Inhibit Neurodegeneration and Enhance Memory in Alzheimer’s Disease Models. The abstract describes Mouse model; reported duration 60 days. The abstract reports: These results suggest that H therapy can mitigate toxic metabolites in the astrocytic urea cycle, thereby reducing neurodegeneration and memory loss in AD. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline improves memory function in a rat model of amyloid-beta-induced Alzheimer’s disease by reduction of oxidative stress.

This animal study examined Hydrogen-rich saline improves memory function in a rat model of amyloid-beta-induced Alzheimer’s disease by reduction of oxidative stress. The abstract describes Rat model; sample size 84; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 14 days. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline attenuates isoflurane-induced caspase-3 activation and cognitive impairment via inhibition of isoflurane-induced oxidative stress, mitochondrial dysfunction, and reduction in ATP levels.

This animal study examined Hydrogen-rich saline attenuates isoflurane-induced caspase-3 activation and cognitive impairment via inhibition of isoflurane-induced oxidative stress, mitochondrial dysfunction, and reduction in ATP levels. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Our results suggest that HS attenuates isoflurane-induced caspase-3 activation and cognitive impairment via inhibition of isoflurane-induced oxidative stress, mitochondrial dysfunction, and reduction in ATP…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich water ameliorates neuropathological impairments in a mouse model of Alzheimer’s disease through reducing neuroinflammation and modulating intestinal microbiota

This animal study examined Hydrogen-rich water ameliorates neuropathological impairments in a mouse model of Alzheimer’s disease through reducing neuroinflammation and modulating intestinal microbiota. The abstract describes Mouse model; hydrogen delivered as hydrogen water and injected or infused hydrogen; reported duration 7 months. The abstract reports: The results showed that hydrogen-rich water prevented synaptic loss and neuronal death, inhibited senile plaques, and reduced hyperphosphorylated tau and neurofibrillary tangles in 3×Tg…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich water improves cognitive impairment gender-dependently in APP/PS1 mice without affecting Aβ clearance.

This animal study examined Hydrogen-rich water improves cognitive impairment gender-dependently in APP/PS1 mice without affecting Aβ clearance. The abstract describes Mouse model; hydrogen delivered as hydrogen water and injected or infused hydrogen. The abstract reports: Molecular hydrogen, which has been proposed to be an antioxidant that selectively reduces reactive oxygen species, was found to exert beneficial effects in Aβ…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Therapeutic potential of hydrogen-rich water in zebrafish model of Alzheimer’s disease: targeting oxidative stress, inflammation, and the gut-brain axis.

This animal study examined Therapeutic potential of hydrogen-rich water in zebrafish model of Alzheimer’s disease: targeting oxidative stress, inflammation, and the gut-brain axis. The abstract describes Zebrafish model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective Effect of Molecular Hydrogen Following Different Routes of Administration on D-Galactose-Induced Aging Mice.

This animal study examined Protective Effect of Molecular Hydrogen Following Different Routes of Administration on D-Galactose-Induced Aging Mice. The abstract describes Mouse model. The abstract reports: H can prevent oxidative stress in D-galactose-induced aging mice when administered by different routes. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen Treatment Protects against Cell Death and Senescence Induced by Oxidative Damage.

This animal study examined Hydrogen Treatment Protects against Cell Death and Senescence Induced by Oxidative Damage. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: Thus, this study showed the antioxidant and anti-senescence effects of hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

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