Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In mice, as shown in Figure 2h, PFOB NEs have an excellent hydrogen‐carrying capacity of ≈ 6 mM, which is about eight times higher than that of water. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and…
Read ArticleIn rabbits, here, the researchers found that I/R-challenged animals showed significant spinal cord damage characterized by the decreased numbers of normal motor neurons and hind-limb motor dysfunction, which…
Read ArticleIn mice, hydrogen gas concentrations in maternal livers and whole fetuses in EFA-FOS were significantly higher than those in CONT and EFA, respectively (P <.05). These preclinical findings…
Read ArticleIn rats, another limitation to the study is related to the lack of measurement of hydrogen concentration in the arterial blood, which may affect the hypotheses regarding the…
Read ArticleIn rats, however, the reduction of the expression of 8-OHdG, the decrease in the neuronal injury in the hippocampal CA1 sector, and the attenuation in brain water content…
Read ArticleIn rats, exercise increased cleaved caspase-3 expression, and H₂ reduced this response. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways…
Read ArticleIn mice, intermittent hypoxia significantly increased plasma levels of low- and very low-density cholesterol and the amount of 4-hydroxy-2-nonenal-modified protein adducts in the LV myocardium. These preclinical findings…
Read ArticleIn male Wistar rats, during mild SI, H₂ reduced plasma surges of proinflammatory cytokines (TNF-α and IL-6) while caused an increase in plasma IL-10 (anti-inflammatory cytokine) and prevented…
Read ArticleIn mice, HRW-treated mice exhibit improved serum lipid profiles, including decreased levels of low-density lipoprotein (LDL), triglycerides (TG), and total cholesterol (T-CHO), as well as reduced lipid accumulation.…
Read ArticleIn mice, compared with WT-H₂ mice, 5xFAD-Veh mice exhibited increased BAX expression ( p < 0.05) and reduced BCL-2 expression, whereas H₂ treatment in 5xFAD-H₂ mice decreased BAX,…
Read ArticleIn mice, this study showed that administration of H₂-rich saline by peritoneal injection (6 mL/kg/24 h) improved the cognitive deficits and reduced the degree of necrosis, apoptosis, and…
Read ArticleH2HUBB PLAIN-LANGUAGE TAKEAWAY The study adds to the molecular-hydrogen evidence base, but the available record does not support a firm conclusion about therapeutic benefit. Molecular hydrogen leukemia study…
Read ArticleThese preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.
Read ArticleIn male Sprague-Dawley rats, immunofluorescence indicated the expression of glutamate transporter-1 in the spinal ischemia group was significantly decreased compared with the sham group, which was attenuated by…
Read ArticleIn exploring the underlying mechanisms, the researchers found that hydrogen could markedly mitigate the degree of IR-induced ER stress and apoptosis (P < 0.05). These preclinical findings add…
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