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The researchers found that the rate of body weight gain was significantly more increased in MTF+ERW group than MTF+PW group. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.
Read ArticleIn rats, compared with the UUO + DW group, HW administration attenuated tubulointerstitial injury and reduced interstitial fibrotic area, causing a substantial decline in the frequency of α-SMA-,…
Read ArticleIn mice, however, HRW prevented retinal thinning and reduced the number of high reflex zones in the RPE layer in mice that received HRW-treatment (Figure 1C, P <…
Read ArticleIn an animal model, undamaged neuron numbers were significantly higher in the HI-H₂ group than in the HI group (p < 0.01), although RT-aEEG was not different. These…
Read ArticleIn an animal model, H₂-RA ventilation significantly increased CR to hypercapnia after A/R (% vasodilation was 23 ± 4% versus 41 ± 9%, p < 0.05). These preclinical…
Read ArticleIn rats, these data suggested that pharmacological postconditioning with lactic acid and hydrogen rich saline nearly replicates the benefits of mechanical postconditioning. These preclinical findings add evidence supporting…
Read ArticleIn an animal model, the percentage of piglets with an abnormal aEEG background (aEEG-BG), abnormal aEEG-BG+Sz and SE was lower with TH + H₂ than with TH at…
Read ArticleIn rats, hydrogen-rich water can improve the radiation-induced cognitive impairment in rats induced by ionizing radiation through anti-inflammation, anti-oxidation, and regulation of PI3K/AKT/Caspase-9 pathway, and there is a…
Read ArticleIn rats, immunohistochemically, 8-OHdG, MDA, and Bax expressions increased in the gentamicin group compared to the control group, whereas they decreased in the gentamicin+hydrogen group compared to the…
Read ArticleIn SH-SY5Y cells, H₂ treatment significantly improved cell viability, attenuated oxidative stress and mitochondrial dysfunction, and enhanced mitophagy via activation of the PINK1/Parkin pathway. The authors linked these…
Read ArticleIn mice, compared with the sham operation and hydrogen control groups, in the sepsis group, the number of normal pyramidal neurons in the hippocampal CA1 region was markedly…
Read ArticleIn Wistar rats, pathological tissue sections showed liver enlargement, injury, and fatty liver in the rats; Compared with the HMD group rats, the HMD+HRW group rats showed a…
Read ArticleIn mice, taking together, these results suggested that besides a high dose of H₂ towards IR-sited tissues for inflammation scavenging and anti-IR, oral administration of Zn-Fe can also…
Read ArticleIn male Wistar rats, during reperfusion, several mechanisms can induce secondary neuronal damage, including the increased production of reactive oxygen species (ROS). These preclinical findings add evidence supporting…
Read ArticleThe researchers observed a significant increase in the concentration of H₂ in the placenta after the oral administration of hydrogen-saturated water to the mothers, with less placental oxidative…
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