Engineering a Tumor‐Targeted MgH 2 @Lip/PD‐L1 Nanoplatform for Synergistic Hydrogen Therapy and Immune Activation

This animal study examined Engineering a Tumor‐Targeted MgH 2 @Lip/PD‐L1 Nanoplatform for Synergistic Hydrogen Therapy and Immune Activation. The abstract describes Animal model; hydrogen delivered as hydrogen inhalation. This is an automated editorial draft based on the abstract and requires source review before publication.

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The Preventive Role of Hydrogen-Rich Water in Thioacetamide-Induced Cholangiofibrosis in Rat Assessed by Automated Histological Classification.

This animal study examined The Preventive Role of Hydrogen-Rich Water in Thioacetamide-Induced Cholangiofibrosis in Rat Assessed by Automated Histological Classification. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: RNA-seq analysis revealed that H results in a decline in glycolysis. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen inhibits the proliferation and migration of gastric cancer cells by modulating lncRNA MALAT1/miR-124-3p/EZH2 axis.

This animal study examined Hydrogen inhibits the proliferation and migration of gastric cancer cells by modulating lncRNA MALAT1/miR-124-3p/EZH2 axis. The abstract describes Mouse model. The abstract reports: These data demonstrated that H might be developed as a therapeutics of gastric cancer and lncRNA MALAT1/miR-124-3p/EZH2 axis could be a target for intervention. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen protects mice from radiation induced thymic lymphoma in BALB/c mice.

This animal study examined Hydrogen protects mice from radiation induced thymic lymphoma in BALB/c mice. The abstract describes Mouse model. The abstract reports: Here in this study, we found that H(2) protects mice from radiation induced thymic lymphoma in BALB/c mice. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-Rich Saline Attenuates Cardiac and Hepatic Injury in Doxorubicin Rat Model by Inhibiting Inflammation and Apoptosis.

This animal study examined Hydrogen-Rich Saline Attenuates Cardiac and Hepatic Injury in Doxorubicin Rat Model by Inhibiting Inflammation and Apoptosis. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: In this study, we found that intraperitoneal injection of hydrogen-rich saline (H saline) ameliorated the mortality, cardiac dysfunction, and histopathological changes caused by DOX…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen alleviates nephrotoxicity induced by an anti-cancer drug cisplatin without compromising anti-tumor activity in mice.

This uncontrolled human study examined Molecular hydrogen alleviates nephrotoxicity induced by an anti-cancer drug cisplatin without compromising anti-tumor activity in mice. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: Hydrogen has potential for improving the quality of life of patients during chemotherapy by efficiently mitigating the side effects of cisplatin. This is an automated editorial draft based on the abstract and requires source review before publication.

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Consumption of hydrogen-rich water protects against ferric nitrilotriacetate-induced nephrotoxicity and early tumor promotional events in rats.

This animal study examined Consumption of hydrogen-rich water protects against ferric nitrilotriacetate-induced nephrotoxicity and early tumor promotional events in rats. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: We found that consumption with HW ameliorated Fe-NTA-induced renal injuries including suppressing elevation of serum creatinine and blood urea nitrogen and inhibited early tumor…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas improves photothermal therapy of tumor and restrains the relapse of distant dormant tumor.

This animal study examined Hydrogen gas improves photothermal therapy of tumor and restrains the relapse of distant dormant tumor. The abstract describes Mouse model. The abstract reports: Inflammation during photothermal therapy (PTT) of tumor usually results in adverse consequences. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-water enhances 5-fluorouracil-induced inhibition of colon cancer.

This animal study examined Hydrogen-water enhances 5-fluorouracil-induced inhibition of colon cancer. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: Furthermore, hydrogen water enhanced cell apoptosis in cancer cells, resulting in a marked increase in the expression of p-AMPK, AIF and Caspase 3 in…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hyperbaric hydrogen therapy: a possible treatment for cancer.

This animal study examined Hyperbaric hydrogen therapy: a possible treatment for cancer. The abstract describes Mouse model. The abstract reports: Marked aggression of the tumors was found, leading to the possibility that hyperbaric hydrogen therapy might also prove to be of significance in the…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular Hydrogen Attenuates Chronic Inflammation and Delays the Onset of Ultraviolet B-Induced Skin Carcinogenesis in Mice.

This animal study examined Molecular Hydrogen Attenuates Chronic Inflammation and Delays the Onset of Ultraviolet B-Induced Skin Carcinogenesis in Mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water and hydrogen inhalation. The abstract reports: These findings suggest that continuous H administration attenuates inflammation-associated early UVB carcinogenesis through modulation of the IL-6/STAT3 and ERK/JNK pathways, supporting its use as…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich water exerts anti-tumor effects comparable to 5-fluorouracil in a colorectal cancer xenograft model

This animal study examined Hydrogen-rich water exerts anti-tumor effects comparable to 5-fluorouracil in a colorectal cancer xenograft model. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: Administration of HRW, with or without 5-FU, may serve as a therapeutic for treating CRC. This is an automated editorial draft based on the abstract and requires source review before publication.

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Controlled release of hydrogen by implantation of magnesium induces P53-mediated tumor cells apoptosis.

This animal study examined Controlled release of hydrogen by implantation of magnesium induces P53-mediated tumor cells apoptosis. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation and hydrogen-rich saline. The abstract reports: We find that the localized release of hydrogen increases the expression level of P53 tumor suppressor proteins, as demonstrated by the RNA sequencing and…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas represses the progression of lung cancer via down-regulating CD47.

This animal study examined Hydrogen gas represses the progression of lung cancer via down-regulating CD47. The abstract describes Mouse model. The abstract reports: In our previous study, our project group found that H2 could decrease the expression of CD47 in lung cancer A549 cells via the next-generation…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen inhibits endometrial cancer growth via a ROS/NLRP3/caspase-1/GSDMD-mediated pyroptotic pathway

This animal study examined Hydrogen inhibits endometrial cancer growth via a ROS/NLRP3/caspase-1/GSDMD-mediated pyroptotic pathway. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: This study extended our original analysis of the ability of hydrogen to stimulate NLRP3 inflammasome/GSDMD activation in pyroptosis and revealed possible mechanism (s) for…. This is an automated editorial draft based on the abstract and requires source review before publication.

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