Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In rats, however, it is unclear whether H₂ affects gene expression directly or through indirect effects as a consequence of health improvement. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.
Read ArticleThe results collectively indicated that hydrogen significantly attenuated CUMS-induced depressive-like behavior and monoamine neurotransmitter deficiency, as well as protected the brain from oxidative stress and inflammatory damage and…
Read ArticleIn mice, the administration of hydrogen gas significantly attenuated the behavioral deficits observed in the authors' bmTBI model, suggesting that hydrogen application might be a strong therapeutic method…
Read ArticleIn rats, these findings suggest that MSN-mediated hydrogen delivery is an effective strategy to address PTSD-associated affective dysfunction by orchestrating neuroimmune responses and synaptic homeostasis. These preclinical findings…
Read ArticleIn male C57BL/6 mice, due to the anti-oxidative function of molecular hydrogen, the hydrogen-rich saline injections reduced METH-induced reactive oxygen species and malondialdehyde generation in the NAc. These…
Read ArticleIn mice, cUMS induced elevation in IL-1β protein levels in the hippocampus, and the cortex was significantly attenuated after 4 weeks of feeding the mice hydrogen-rich water. These…
Read ArticleIn mice, the number of activated astrocytes with hypertrophic morphology was increased in LPS-exposed offspring, but decreased in the offspring of H₂-administered dams. These preclinical findings add evidence…
Read ArticleIn mice, post hoc analysis showed that HRW administration in PVS and PVL groups significantly attenuated the increased serum levels of TNF-α of male ( P < 0.05,…
Read ArticleIn mice, cEO administration and H₂ inhalation alone or in combination positively improved inflammation-induced anxiety, depression, and cognitive memory deficits in the mice. These preclinical findings add evidence…
Read ArticleThe researchers found that HRS administration significantly reduced body weight loss, jumping behavior and wet-dog shakes in mice underwent naloxone-precipitated withdrawal, and attenuated anxiety-like behaviors in the EPM…
Read ArticleIn mice, consistent with the authors' previous report, 10 HI insult significantly increased brain water content (90.73 ± 1.04%) as compared with that observed in the Sham group…
Read ArticleIn mice, treatment with HRW intraperitoneally administered at 2T per day over two consecutive days normalized the increased immobility time observed in CFA-injected animals treated with VEH in…
Read ArticleIn male Wistar rats, HRW treatment consistently reduced MDA levels and substantially restored catalase activity in the liver and testis (p < 0.05, p < 0.01). The combined…
Read ArticleIn mice, the H₂ concentration immediately increased in the liver but not in the kidney after drinking HW. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential…
Read ArticleIn contrast, H₂ treatment significantly suppressed the signs of I/R injury in fatty liver. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and…
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