Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
The researchers showed that 8-OHdG, but not MDA, significantly increased by 149% and 145% in HU-NW and HU-AEW, respectively, when compared with CONT. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this…
Read ArticleIn mice, table 1 Effects of molecular hydrogen-dissolved alkaline electrolyzed water on physical parameters at 4 weeks of treatment Biochemical parameters of the serum obtained from mice administered…
Read ArticleIn mice, the pivotal proteins involved in endoplasmic reticulum (ER) stress, including p-eIF2α, ATF4, XBP1s and CHOP, were dramatically reduced after HRW treatment in contrast to the control…
Read ArticleIn rats, the oxidative stress levels of MDA and MPO in the gastric tissues increased significantly in the aspirin-treated group compared with the HRW group (2.43 ± 0.145…
Read ArticleIn an animal model, body mass was 36.4 (35.1–37.9) and 36.9 (34.4–38.4) kg in the control and hydrogen groups, respectively ( p = 0.89). These preclinical findings add…
Read ArticleThe findings suggest that treatment with molecular hydrogen may affect microbiota profiling and suppress intestinal injury in HFD-loaded SAMP8. These preclinical findings add evidence supporting molecular hydrogen's therapeutic…
Read ArticleIn the intestinal tissue, compared with the LPS group, the HRW + LPS group had decreased the levels of IL-1β and TNF-α ( Figure 2 B, p <…
Read ArticleIn mice, although sulfasalazine significantly reduced MDA levels compared to the colitis model (P < 0.001), H₂ with and without sulfasalazine was significantly more effective compared to sulfasalazine…
Read ArticleIn male Wistar rats, the serum levels of TNF-α, IL-1β, and IL-6 were significantly increased 12 h after the onset of AP ( Fig 3A ), and the…
Read ArticleIn rats, hydrogen-rich saline also increased B-cell lymphoma 2 (Bcl-2) expression and the activity of the antioxidant enzyme superoxide dismutase (SOD). These preclinical findings add evidence supporting molecular…
Read ArticleIn rats, HRW treatment effectively alleviated the degenerative changes in the retinal outer nuclear layer, improved retinal function, and reduced retinal inflammation in treated rats. These preclinical findings…
Read ArticleIn mice, H₂ mice showed significantly higher retinal thickness as compared to controls on optical coherence tomography. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within…
Read ArticleThe researchers found that hydrogen decreased the expression of the DNA damage-related protein ATM, cyclinD1 and NF-κB but increased the expression of the DNA repair-related protein HMGB1, suggesting…
Read ArticleCorneal alkali burns are potentially blinding injuries. Alkali induces oxidative stress in corneas followed by excessive corneal inflammation, neovascularization, and untransparent scar formation. Molecular hydrogen (H), a potent…
Read ArticleIn rats, 3 Hydrogen gas improved BRVO rat microcirculation at 7 d post-occlusion. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological…
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