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In rats, hRSS is effective in reducing the intestinal damage caused by an IRI: HRSS has the potential to reduce the detrimental effects of intestinal anastomosis performed after an intestinal IRI. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within…
Read ArticleIn rats, however, hydrogen-rich saline treatment significantly increased the 24-h survival of rats to 53.33% (8 of 15 rats) in the HRS1 group and 86.67% (13 of 15…
Read ArticleIn rats, this study provides biochemical and histomorphological evidence that HRSS prevents intestinal damage in I/R injury caused by volvulus. These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleIn male C57BL/6 mice, HRW treatment partially ameliorated colitis symptoms, improved histopathological changes, significantly increased glutathione (GSH) concentration and decreased TNF-α level. These preclinical findings add evidence supporting…
Read ArticleIn rats, meanwhile, the increased MPO level in the EHW-administered group significantly reduced 2 ( p = 0.0011) and 4 ( p = 0.0009) days post TNBS treatment…
Read ArticleIn rats, the authors' present study showed that hydrogen treatment lessened the stress-induced lipid peroxidation, protein carbonyl and DNA oxidant and improved tissue antioxidant potential. These preclinical findings…
Read ArticleIn rats, plasma cytokines concentrations were reduced in H₂ saline-treated TP rats. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways…
Read ArticleIn mice, bowel dysmotility, induced by surgical manipulation and inflammatory events, was significantly attenuated by intra-abdominal administration of hydrogen-rich saline. These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleIn rats, although enhanced MDA levels were observed in all of the injured animals, the elevation appeared to be significantly inhibited by hydrogen-rich saline treatment ( P <…
Read ArticleIn Sprague-Dawley rats, the serum tumor necrosis factor-α content increased significantly in I/R + saline group, but HRW treatment reduced serum tumor necrosis factor-α content as compared to…
Read ArticleIn male Sprague-Dawley rats, hydrogen-rich saline reduced these markers and relieved morphological intestinal injury, while no significant reduction was observed in the nitrogen-rich saline-treated animals. These preclinical findings…
Read ArticleIn rats, experimental protocols were divided into four groups: sham operation group, no luminal injection (control) group, luminal injection of 5% glucose saline (GS) solution group, and luminal…
Read ArticleIn rats, histopathological mucosal erosion and increased gut permeability indicated a breakdown in posttransplant mucosal barrier function which was significantly attenuated by hydrogen treatment. These preclinical findings add…
Read ArticleIn Sprague-Dawley rats, hRS treatment maintained the body weight, reduced the incidence of NEC from 85% (17/20) to 54.5% (12/22), increased the survival rate from 25% (5/20) to…
Read ArticleIn rats, treatment with hydrogen-rich saline reduced the weight loss and diarrhea and alleviated the colonic mucosal damage in the UC rats. These preclinical findings add evidence supporting…
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