Hydrogen inhalation is neuroprotective and improves functional outcomes in mice after intracerebral hemorrhage.
This animal study examined Hydrogen inhalation is neuroprotective and improves functional outcomes in mice after intracerebral hemorrhage. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: Our results suggest that hydrogen inhalation exerts an acute brain-protective effect in the mouse ICH model. However, the acute hydrogen therapy alone is not…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline attenuates hippocampus endoplasmic reticulum stress after cardiac arrest in rats
This animal study examined Hydrogen-rich saline attenuates hippocampus endoplasmic reticulum stress after cardiac arrest in rats. The abstract describes Rat model; sample size 30; hydrogen delivered as hydrogen-rich saline. The abstract reports: Hydrogen-rich saline attenuates brain I/R injury may through inhibiting hippocampus ERS after cardiac arrest in rats. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen improves neurological function through attenuation of blood-brain barrier disruption in spontaneously hypertensive stroke-prone rats.
This animal study examined Hydrogen improves neurological function through attenuation of blood-brain barrier disruption in spontaneously hypertensive stroke-prone rats. The abstract describes Rat model; sample size 28; hydrogen delivered as hydrogen water. The abstract reports: The present study suggests that ingestion of HRW can improve neurological function outcome in the SHRSP model. This beneficial effect may be due to…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreNeuroprotective Effect of Hydrogen-Rich Saline in Global Cerebral Ischemia/Reperfusion Rats: Up-Regulated Tregs and Down-Regulated miR-21, miR-210 and NF-κB Expression.
This animal study examined Neuroprotective Effect of Hydrogen-Rich Saline in Global Cerebral Ischemia/Reperfusion Rats: Up-Regulated Tregs and Down-Regulated miR-21, miR-210 and NF-κB Expression. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Recently, it has been suggested that molecular hydrogen (H) can selectively reduce the levels of hydroxyl radicals (.OH), and ameliorate oxidative and inflammatory injuries…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInfluence of oxygen concentration on the neuroprotective effect of hydrogen inhalation in a rat model of cardiac arrest
This uncontrolled human study examined Influence of oxygen concentration on the neuroprotective effect of hydrogen inhalation in a rat model of cardiac arrest. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: In this CA rat model, inhaling 2% hydrogen combined with a high concentration of oxygen improved 96-h survival, either under normothermia or under hypothermia. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline protects against oxidative damage and cognitive deficits after mild traumatic brain injury.
This uncontrolled human study examined Hydrogen-rich saline protects against oxidative damage and cognitive deficits after mild traumatic brain injury. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline. The abstract reports: Oxidative stress is the principal factor in traumatic brain injury (TBI) that initiates events that result in protracted neuronal dysfunction and remodeling. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas inhalation improves delayed brain injury by alleviating early brain injury after experimental subarachnoid hemorrhage.
This in vitro or cellular study examined Hydrogen gas inhalation improves delayed brain injury by alleviating early brain injury after experimental subarachnoid hemorrhage. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen inhalation. The abstract reports: CV showed no significant improvement between the control and H groups. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhalation of hydrogen gas attenuates cognitive impairment in transient cerebral ischemia via inhibition of oxidative stress.
This animal study examined Inhalation of hydrogen gas attenuates cognitive impairment in transient cerebral ischemia via inhibition of oxidative stress. The abstract describes Rat model; sample size 30; reported duration 3 hours. The abstract reports: Inhalation of hydrogen gas could attenuate cognitive impairment in the ischemic rats. This protection is associated with decreased neuronal death in CA1 region and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEfficacy of inhaled HYdrogen on neurological outcome following BRain Ischemia During post-cardiac arrest care (HYBRID II trial): study protocol for a randomized controlled trial.
This study protocol examined Efficacy of inhaled HYdrogen on neurological outcome following BRain Ischemia During post-cardiac arrest care (HYBRID II trial): study protocol for a randomized controlled trial. The abstract describes Planned or registered research population; hydrogen delivered as hydrogen inhalation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline improves survival and neurological outcome after cardiac arrest and cardiopulmonary resuscitation in rats.
This uncontrolled human study examined Hydrogen-rich saline improves survival and neurological outcome after cardiac arrest and cardiopulmonary resuscitation in rats. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Hydrogen-rich saline treatment improved survival and neurological outcome after cardiac arrest/resuscitation in rats, which was partially mediated by reducing oxidative stress, inflammation, and apoptosis. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe neuroprotective effects of intraperitoneal injection of hydrogen in rabbits with cardiac arrest.
This animal study examined The neuroprotective effects of intraperitoneal injection of hydrogen in rabbits with cardiac arrest. The abstract describes Rabbit model; hydrogen delivered as injected or infused hydrogen. The abstract reports: Intraperitoneal injection of H2 is a novel hydrogen administration method and can reduce cerebral ischemia-reperfusion injury and improve the prognosis of cardiopulmonary cerebral resuscitation…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas with extracorporeal cardiopulmonary resuscitation improves survival after prolonged cardiac arrest in rats.
This uncontrolled human study examined Hydrogen gas with extracorporeal cardiopulmonary resuscitation improves survival after prolonged cardiac arrest in rats. The abstract describes Human participants. The abstract reports: H therapy improved mortality in highly lethal CA rats rescued by ECPR and helped recover brain electrical activity. The underlying mechanism might be linked…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of hydrogen-rich saline in a rat model of traumatic brain injury via reducing oxidative stress.
This uncontrolled human study examined Protective effects of hydrogen-rich saline in a rat model of traumatic brain injury via reducing oxidative stress. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Hydrogen-rich saline can exert a protective effect against TBI via reducing oxidative stress. Molecular hydrogen may be a more effective therapeutic strategy for TBI…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Inhalation During Normoxic Resuscitation Improves Neurological Outcome in a Rat Model of Cardiac Arrest Independently of Targeted Temperature Management
This animal study examined Hydrogen Inhalation During Normoxic Resuscitation Improves Neurological Outcome in a Rat Model of Cardiac Arrest Independently of Targeted Temperature Management. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: H2 inhalation was beneficial when begun after ROSC, even when delivered in the absence of hyperoxia. Combined TTM and H2 inhalation was more effective…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffect of hydrogen gas on the survival rate of mice following global cerebral ischemia.
This animal study examined Effect of hydrogen gas on the survival rate of mice following global cerebral ischemia. The abstract describes Mouse model; sample size 12. The abstract reports: Global cerebral ischemia and reperfusion (I/R) often result in high mortality. This is an automated editorial draft based on the abstract and requires source review before publication.
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