Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In rats, s-nitroso-N-acetylpenicillamine treatment decreased the cell numbers in the ganglion cell layer and inner nuclear layer, but the presence of H₂ inhibited this reduction. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured…
Read ArticleIn rats, the pre-exercise supplement of vitamin C significantly reduced mitochondrial complex IV concentrations and PGC-1α, NRF-1, TFAM gene expression levels compared to the pre-exercise group, but the…
Read ArticleIn male Sprague-Dawley rats, the exercise tolerance of rats in the HW group significantly improved, and the distribution and diversity of intestinal microbes were altered. These preclinical findings…
Read ArticleIn conclusion, findings from this study suggest that ingesting hydrogen-rich cold water effectively mitigates the effects of heat stress, thereby improving endurance performance, enhancing mood, and reducing ratings…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Disease and noxious forms of exercise promote redox dysregulation and chronic inflammation, changes that are mitigated by H₂ administration. The…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
Read ArticleIn rats, similarly, coenzyme Q9 levels in the rat plasma, myocardial tissue, and mitochondria were increased and malondialdehyde level in plasma was reduced after HRW administration. These preclinical…
Read ArticleIn rats, compared with MP, MP-H₂ treatment reduced lysophosphatidylinositol (LPI) levels and the LPI/phosphatidylinositol ratio while increasing phosphatidic acid (PA) species such as PA (18:0/18:1) and PA (18:0/20:4).…
Read ArticleIn rats, kEY FINDINGS: The myocardial infarct size, no-reflow area, cardiac function, microstructure and mitochondrial morphology of I/R model rats were significantly improved after hydrogen inhalation. These preclinical…
Read ArticleThis publication is an erratum or correction associated with a molecular-hydrogen article. It does not report a new standalone experiment.
Read ArticleIn rats, myocardial injury and inflammatory events were significantly attenuated by organ storage in the hydrogen-rich water bath. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential…
Read ArticleThe researchers found that hydrogen-rich medium can increase ATP content, mitochondrial membrane potential and maximal respiration rate, and decrease the expression of Drp1 in LPS-treated HUVECs. The authors…
Read ArticleIn rats, nFkB-p65 and c-Fos in the nucleus were unexpectedly unchanged by IRI regardless of H₂ treatment, indicating the absence of inflammation in this model. These preclinical findings…
Read ArticleIn Sprague-Dawley rats, the purpose of the present study was to determine whether using hydrogen-rich medium (HRM) to increase hydrogen levels in endothelial cells (ECs) protects ECs from…
Read ArticleIn Sprague Dawley rats, hRS treatment significantly increased the viability of myocardial cells, reduced the rate of myocardial cellular apoptosis and the release of MDA and LDH compared…
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