Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In male Sprague-Dawley rats, compared with the OLT group, HRS dramatically attenuated the histopathologic damage, restored the renal function, and decreased the oxidative stress level. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. The delivery of molecular hydrogen (H₂) is increasingly recognized for its potential in precision immunomodulation, primarily through multiple pathways such…
Read ArticleIn 30 patients with NAFLD and 15 healthy volunteers were included in this clinical trial, after 8 weeks of adjuvant therapy with HRW, the concentration of CoQ10 in…
Read ArticleIn rats, the data indicate that 1-month treatment of N-acetylcysteine or hydrogen-rich saline significantly ameliorated systemic and splanchnic hyperdynamic circulation, corrected hepatic endothelial dysfunction, and decreased intrahepatic resistance…
Read ArticleIn mice, inhalation of hydrogen gas (1-4%) during the last 190min suppressed hepatic cell death, and reduced levels of serum alanine aminotransferase and hepatic malondialdehyde. These preclinical findings…
Read ArticleIn an animal model, white blood cells in the HRS-10 group were reduced compared with the IRI group (P < 0.01). These preclinical findings add evidence supporting molecular…
Read ArticleIn male Sprague-Dawley rats, hydrogen-rich saline attenuates BDL-induced liver damage, possibly by the reduction of inflammation and oxidative stress and the inhibition of the ERK1/2 pathway. These preclinical…
Read ArticleIn an animal model, however, ALT and AST activity significantly decreased at T3h and T1d and AKP activity significantly decreased at T1d in the IRI + hydrogen-rich saline…
Read ArticleIn rats, hydrogen gas reduced hepatic reperfusion injury after prolonged cold preservation via the maintenance of portal flow, by protecting mitochondrial function during the early phase of reperfusion,…
Read ArticleThe researchers found that saturated hydrogen saline treatment efficiently decreased the activation of ERK and JNK, while promoting the activation of p38 (P<0.05 compared with LPS), suggesting the…
Read ArticleIn rats, no significant differences in dissolved H₂ or ORP values were observed in the HRW samples either at 4 °C or at 25 °C within 24 h.…
Read ArticleIn rats, the hydrogen-rich UW solution group also showed less oxidative damage and hepatocyte apoptosis than the control group, and the expression of proinflammatory cytokines tended to be…
Read ArticleIn mice, the HW group showed a smaller decrease in hepatic cholesterol; however, stronger antioxidative effects in serum and lower peroxisome proliferator-activated receptor-α expression in the liver were…
Read ArticleIn an animal model, liver samples in the group with inhaled hydrogen showed a statistically significant reduction in histological changes compared to the control group. These preclinical findings…
Read ArticleIn an animal model, apoptosis in cholangiocytes isolated from a rat model of liver ischemia/reperfusion injury indicated that H₂ significantly attenuates ischemia/reperfusion cholangiocyte injury in vivo. These preclinical…
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