Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In male Sprague-Dawley rats, however, administration of HS significantly reduced the injury score. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.
Read ArticleIn rats, all these factors were significantly improved by both doses of HRS, but the mean histologic damage score, urea, Cr, CK, ROS, 8-OH-dG, GSH-PX, IL-6, and TNF-α…
Read ArticleIn Sprague-Dawley rats, the activated pro-apoptotic kinase JNK (p-JNK) exhibited increased expression after burn injury, and the most significant elevation was observed at 72 h post burn (all…
Read ArticleIn male Sprague-Dawley rats, cytoprotective effects of the dual treatment in comparison with H₂ treatment and I-R renal injury were observed in terms of superoxide radical scavenging activity…
Read ArticleIn mice, the renal expressions of osteopontin (OPN), CD44, monocyte chemoattractant protein-1 (MCP-1) and interleukin-10 (IL-10) were markedly increased in glyoxylate-treated mice, and H₂ significantly attenuated the increase…
Read ArticleIn the early phases, HRUW solution decreased oxidative stress, tubular apoptosis, and interstitial macrophage infiltration in the kidney grafts. These preclinical findings add evidence supporting molecular hydrogen's therapeutic…
Read ArticleIn rats, one day after the injection, serum levels of urea nitrogen were significantly lower in H₂ gas-inhaling CIAKI rats (17.6 ± 2.3 mg/dl) than those in control…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Clinical studies have reported that systemic oxidative stress in patients undergoing dialysis treatment using EHW is suppressed, leading to a…
Read ArticleIn conclusion, HRW restored the balance of redox status, suppressed oxidative stress damage, and improved kidney function induced by CsA via activation of the Keap1/Nrf2 signaling pathway. The…
Read ArticleIn mice, crystal deposition, tubular injury, fibrosis and increased ROS production in kidneys of mice induced by oxalate diet were improved with HRW administration. These preclinical findings add…
Read ArticleIn rats, this experiment showed that the effect of drinking large volumes of hydrogen-rich water was not significantly different from that of normal water, in terms of preventing…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. H₂ consistently demonstrated protective effects against apoptosis, fibrosis, inflammation, and oxidative stress across acute kidney injury, nephrotoxicity, transplantation, and early…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Its main pathological features are inflammatory reaction, increased secretion, mucosal swelling and thickening of nasal cavity or paranasal sinuses.It mainly…
Read ArticleIn Reactive oxygen species (ROS) are highly reactive and directly attack surrounding biomolecules to deteriorate cellular and tissue functions, meanwhile, ROS also serve as signaling mediators to upregulate…
Read ArticleIn guinea pigs, hRS reduced the ROS and MDA levels and increased SOD level in guinea pigs of AR-HRS group accompanied with decreased frequency of sneezing and scratches.…
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