Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
This narrative review examined the available molecular-hydrogen literature. The authors highlighted early evidence of cytoprotective, antioxidant, and anti-inflammatory effects. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
Read ArticleIn rats, H₂ improved HO-1 mRNA and protein expression and activities in the process of pain. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the…
Read ArticleIn a laboratory model, hydrogen gas can reduce cytotoxic reactive oxygen species (ROS) that are produced in inflamed tissues. The authors concluded that experimental results indicate that the…
Read ArticleIn mice, repeated inhalation of hydrogen-oxygen mixed gas [67%:33% (V/V)] significantly decreased both the acute and chronic stress-induced depressive- and anxiety-like behaviors of mice, assessed by tail suspension…
Read ArticleIn mice, the inhalation of H₂ (2%) or hyperoxia (98%) alone improved the 14-day survival rate of ZY-challenged mice from 20 to 70 or 60%, respectively. These preclinical…
Read ArticleThe researchers found that resuscitation by hydrogen-rich saline alleviated inflammation significantly. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured…
Read ArticleThe researchers found that oral intake of hydrogen-rich water abolishes an immediate-type allergic reaction in mice. The authors concluded that the authors' studies also suggest that hydrogen is…
Read ArticleIn mice, 3.3 Immunoblot analysis of the tibialis cranialis muscle showed that Nrf2 protein expression was significantly lower in the HRW group than in the PW group, both…
Read ArticleIn This ex vivo study investigated whether ECMO could serve as an effective vehicle for hydrogen delivery, hydrogen exposure significantly reduced collagen (p = 0.01), TRAP-6 (p =…
Read ArticleIn rats, oxidant status in biochemical analyses decreased in the stress + HRW group compared to the stress group. These preclinical findings add evidence supporting molecular hydrogen's therapeutic…
Read ArticleIn an animal model, the cumulative mortality rate of SVCV-infected zebrafish was reduced by 40% after treatment with nano-bubble hydrogen water, and qRT-PCR results showed that SVCV replication…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Hydrogen selectively targets harmful radicals, and EHW intake helps balance stress-induced hormonal dysregulation, potentially easing disorders associated with chronic stress.…
Read ArticleIn mice, the malonyldialdehyde (MDA) contents were significantly reduced in the HRW pretreatment group, but they were increased in the APAP-treated group (10.44 ± 1.339 nmol/mg protein vs…
Read ArticleIn a laboratory model, the EWP may use a gargle solution and a soaking solution for prevention of oral candidiasis and denture-related stomatitis due to antifungal activity. (J…
Read ArticleIn rats, increased post-void residual volume in obstructed rats was significantly reduced by H₂ water. There was no significant difference in histological findings between rats with bladder obstruction…
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