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Latest Molecular Hydrogen Articles

550 Articles

Hydrogen gas inhalation alleviates myocardial ischemia-reperfusion injury by the inhibition of oxidative stress and NLRP3-mediated pyroptosis in rats.

By H2HUBB Jul 22, 2026 0 Comments

In rats, kEY FINDINGS: The myocardial infarct size, no-reflow area, cardiac function, microstructure and mitochondrial morphology of I/R model rats were significantly improved after hydrogen inhalation. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways…

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Cardioprotective Effect of Hydrogen-rich Saline on Isoproterenol-induced Myocardial Infarction in Rats.

By H2HUBB Jul 22, 2026 0 Comments

In male Wistar rats, compared with those in isoproterenol-MI group, hydrogen-rich saline decreased malondialdehyde and 8-hydroxy-desoxyguanosine concentrations, enhanced superoxide dismutase and Na(+)-K(+)-ATPase activity, lowered Ca(2+)-ATPase activity and decreased…

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Hydrogen gas inhalation ameliorates cardiac remodelling and fibrosis by regulating NLRP3 inflammasome in myocardial infarction rats.

By H2HUBB Jul 22, 2026 0 Comments

This publication is an erratum or correction associated with a molecular-hydrogen article. It does not report a new standalone experiment.

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Acute Effects of Molecular Hydrogen Inhalation on Exercise-Induced Oxidative Stress, Vascular Responses, and Performance in National-Level Female Rowers: An Exploratory Pilot Case Series

By H2HUBB Jul 22, 2026 0 Comments

In 3 participants, during recovery, urinary 8-OH-dG tended to be lower under H₂ (HL-9.9; exact p=0.25), suggesting a potential attenuation of oxidative DNA damage, and venous diameter also…

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Molecular hydrogen attenuates sepsis-induced cardiomyopathy in mice by promoting autophagy.

By H2HUBB Jul 22, 2026 0 Comments

In mice, the survival rate of septic mice treated with H₂ was significantly improved, myocardial tissue inflammation was improved, serum cTnI level was decreased, autophagy flux was increased,…

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Hydrogen Attenuates Thyroid Hormone-Induced Cardiac Hypertrophy in Rats by regulating angiotensin II type 1 receptor and NADPH oxidase 2 mediated oxidative stress.

By H2HUBB Jul 22, 2026 0 Comments

In rats, hydrogen treatment also reduced the levothyroxine-induced increase in cardiac malondialdehyde, 8-hydroxy-2-deoxyguanosine and serum hydrogen peroxide levels and upregulated superoxide dismutase and glutathione peroxidase activity. These results…

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Effects of hydrogen as adjuvant treatment for unstable angina.

By H2HUBB Jul 22, 2026 0 Comments

In The purpose of this study is to evaluate the effect of hydrogen on unstable angina in vitro and in vivo, serum analysis showed that hydrogen-rich water addition…

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Constitutive hydrogen inhalation prevents vascular remodeling via reduction of oxidative stress.

By H2HUBB Jul 22, 2026 0 Comments

In C57BL/6 mice, although the increase in superoxide anion production did not significantly differ between the hydrogen and control groups, DNA damage was decreased as a result of…

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Effect of hydrogen-rich water on the Nrf2/ARE signaling pathway in rats with myocardial ischemia-reperfusion injury.

By H2HUBB Jul 22, 2026 0 Comments

In rats, compared with the ischemic period, the ischemia-reperfusion phase showed significantly increased SOD activity and significantly decreased MDA content in the hydrogen-rich water group, while SOD activity…

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A New Approach for the Prevention and Treatment of Cardiovascular Disorders. Molecular Hydrogen Significantly Reduces the Effects of Oxidative Stress.

By H2HUBB Jul 22, 2026 0 Comments

This narrative review examined the available molecular-hydrogen literature. The authors highlighted early evidence of cytoprotective, antioxidant, and anti-inflammatory effects. The reviewed evidence adds support for molecular hydrogen's therapeutic…

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Hydrogen-rich water prevents lipid deposition in the descending aorta in a rat periodontitis model.

By H2HUBB Jul 22, 2026 0 Comments

In male Wistar rats, hW intake may prevent lipid deposition in the rat aorta induced by periodontitis by decreasing serum ox-LDL levels and aortic oxidative stress. These preclinical…

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Hydrogen-rich saline prevents early neurovascular dysfunction resulting from inhibition of oxidative stress in STZ-diabetic rats.

By H2HUBB Jul 22, 2026 0 Comments

In male Sprague-Dawley rats, sTZ-diabetic rats were marked by clearly reduced b-wave amplitudes and oscillatory potentials, DM-related BRB breakdown and histological changes in the inner retina, all of…

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The Anti-inflammatory Effect of Hydrogen on Lung Transplantation Model of Pulmonary Microvascular Endothelial Cells During Cold Storage Period.

By H2HUBB Jul 22, 2026 0 Comments

In Pulmonary microvascular endothelial cells were divided into 4 groups: blank, control, oxygen (O₂), and H₂, the pH values in the O₂ (7.17 ± 0.05) and H₂ groups…

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Treatment with hydrogen molecule attenuates cardiac dysfunction in streptozotocin-induced diabetic mice.

By H2HUBB Jul 22, 2026 0 Comments

In mice, although treatment of diabetic mice with hydrogen water did not significantly affect blood glucose level, it significantly attenuated cardiac hypertrophy and reduced expression of atrial natriuretic…

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Hydrogen gas protects against serum and glucose deprivation‑induced myocardial injury in H9c2 cells through activation of the NF‑E2‑related factor 2/heme oxygenase 1 signaling pathway.

By H2HUBB Jul 22, 2026 0 Comments

In a laboratory model, xIE et al: Nrf2/HO-1 PATHWAY MEDIATES H₂ GAS MYOCARDIAL PROTECTION114 8 agent CoCl2, at 400 -1,000 µM for 24 h, reduced cell viability in…

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