Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In comparison to control rats given distilled water (DW), the researchers found that HW did not significantly influence systolic blood pressure (SBP) or diastolic blood pressure (DBP) in SHR; however, the increase in SBP and DBP were inhibited in the HWA group.…
Read ArticleThis preclinical study evaluated molecular hydrogen in rats. These results are preclinical and suggest molecular hydrogen's therapeutic potential in the condition studied. Further human research is needed to…
Read ArticleIn participants with systemic lupus erythematosus (SLE), this case study suggests that molecular hydrogen therapy may be a promising treatment for patients with SLE-PAH, particularly due to its…
Read ArticleIn mice, H₂ treatment reduced inflammatory, oxidative, and fibrotic lung changes. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured…
Read ArticleIn mice, the immunofluorescence of cleaved caspase-3 also indicated that H₂ suppressed the expression of cleaved caspase-3 in TBHP-induced chondrocytes ( Figure 5H ). These preclinical findings add…
Read ArticleIn 20 patients with rheumatoid arthritis (RA), during the first 4 weeks, 8-OHdG decreased in 17 of these patients after drinking the high H₂ water. These findings add…
Read ArticleIn 3 patients, iL-17, whose concentration was high in Case 1, was reduced following H₂ treatment, and TNFα also decreased in Case 1. These findings add human evidence…
Read ArticleIn a laboratory model, H₂ decreased the levels of the nitrated proteins, and suppressed chondrocyte death. The authors concluded that moreover, novel pharmacological strategies aimed at selective removal…
Read ArticleRecently, it has been demonstrated that hydrogen gas, known as a novel antioxidant, can exert therapeutic anti-inflammatory effect in many diseases. This source-grounded publication contributes evidence relevant to…
Read ArticleIn rats, drinking hydrogen-rich water suppressed body weight gain, lowered gingival level of 8-hydroxydeoxyguanosine, and reduced alveolar bone resorption in rats on a high-fat diet. These preclinical findings…
Read ArticleIn mice, based on the authors' result, H₂ enriched medium can increase super oxide dismutase (SOD) level following H₂O₂ treatment and decrease 8-hydroxy-2'-deoxyguanosine (8-OHdG) level. These preclinical findings…
Read ArticleIn rabbits, hydrogen-rich saline significantly decreased the levels of VEGF, TM and LPO and increased the GSH level in steroid-associated necrosis of the femoral head in the rabbit…
Read ArticleIn Methotrexate (MTX) remains a cornerstone of RA treatment, offering significant therapeutic benefits, this is the first case report to highlight severe MTX-induced myelosuppression in an RA patient…
Read ArticleIn rats, treatment with HW abated oxidative stress and suppressed IL-6 and TNF-α mRNA expressions in femur of ovariectomized rats; treatment with HW increased femur endothelial NOS activity…
Read ArticleIn rats, hW showed a protective effect against the progression of OA in an animal model, which may have been mediated by its anti-oxidant and anti-apoptotic activities. These…
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