Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In a laboratory model, on day 3 of ischemia/reperfusion, the number of neurons undergoing apoptosis in the cortex was significantly lower in the H₂-rich saline group than in the saline group, and on day 7, the number of viable neurons in the…
Read ArticleIn an animal model, at 10 min, H₂ concentration was significantly higher in venous blood than in arterial blood. These preclinical findings add evidence supporting molecular hydrogen's therapeutic…
Read ArticleIn 8 healthy participants, although these data suggest that inhaled hydrogen gas may be well tolerated, future studies need to be powered to further evaluate safety. These findings…
Read ArticleHydrogen inhalation was associated with greater reductions in systolic and diastolic blood pressure than control treatment through 24 weeks.
Read ArticleIn an animal model, no change in the PH or composition of the solution was observed due to hydrogen filling. These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleIn male Wistar rats, H₂ exposure increased neither comet-tail DNA intensity (DNA damage) nor frequency of "hedgehogs" in blood, liver, lungs, or bronchoalveolar lavage fluid. These preclinical findings…
Read ArticleIn an animal model, after infusion of the H₂-rich glucose solution, H₂ concentration in the portal vein peaked at 0.05 mg/L and remained at more than 0.016 mg/L…
Read ArticleIn 60 participants with hypertension aged 50-70 years, when stratified by age (aged 50-59 years versus aged 60-70 years), participants in the older H₂-O₂ group showed a larger…
Read ArticleIn an animal model, significantly higher partial pressure of arterial oxygen and significantly lower partial pressure of carbon dioxide were observed in the H₂ group than in the…
Read ArticleIn C57BL/6 mice, levels of inflammatory cytokines (interleukin-1β, interleukin-6, and tumor necrosis factor α) and oxidative stress markers (ie, malondialdehyde) were significantly lower, whereas antioxidant enzyme (total superoxide…
Read ArticleThis narrative review examined given the increasing burden of aging-related COPD and the emerging biological effects of molecular hydrogen, the researchers hypothesized that H₂ therapy may exert beneficial…
Read ArticleIn 6 patients, however, no significant differences were observed in lung function, DLCO, sleep quality, and 6 MWT before and after hydrogen therapy. These findings add human evidence…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
Read ArticleIn mice, however, H₂ did not substantially affect the H/R-induced increase in erythropoietin or pulmonary artery remodeling. These preclinical findings add evidence about the molecular-hydrogen effects, outcomes, and…
Read ArticleIn male Sprague-Dawley rats, hydrogen saline significantly protected vasoactivity of the pulmonary artery, reduced pulmonary oedema, decreased lung malondialdehyde (MDA), 8-OHdG concentration, alleviated lung epithelial cellular apoptosis and…
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