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In mice, significant lung injury at 24 h post-TBI got significantly reduced by treatment of 2% H₂. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.
Read ArticleIn mice, however, the reduction was significantly greater in the MGNs-treated group compared to the group treated with 3% H₂, indicating that MGNs have a superior therapeutic effect.…
Read ArticleIn Wistar rats, serum levels of endotoxin, syndecan-1, malondialdehyde, and tumor necrosis factor-α decreased, whereas superoxide dismutase levels increased, indicating that inhalation of 2% hydrogen attenuated the damage…
Read ArticleIn rats, hydrogen gas reduced brain swelling, improved neurological function, and lowered markers of oxidative stress and neuronal pyroptosis after subarachnoid hemorrhage. These preclinical findings add evidence supporting…
Read ArticleIn rats, serum IL-6 levels 2 hours after ROSC were not significantly increased in post-CA rats of the H₂ group (848.9±257.0 pg/mL) or H₂ +TH group (933.3±339.0 pg/mL)…
Read ArticleThis publication is an erratum or correction associated with a molecular-hydrogen article. It does not report a new standalone experiment.
Read ArticleIn 429 patients with a 90-day Cerebral Performance Category (CPC) of 1 or 2 assessed in a full-analysis set, the Cox proportional hazards model showed a lower adjusted…
Read ArticleThis publication is an erratum or correction associated with a molecular-hydrogen article. It does not report a new standalone experiment.
Read ArticleIn male Wistar rats, however, inhalation of H₂ gas after ROSC significantly decreased the number of abnormal mitochondria and increased the relative mitochondrial mass in rat LVs, and…
Read ArticleIn the H₂ treatment group (group H), these proteins were significantly decreased. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways…
Read ArticleIn an animal model, nissl staining demonstrated a significant decrease in the number of nissl-stained dark neurons (N-DNs) in HI group compared to TBI group at 2 h…
Read ArticleIn Neuronal degeneration within hippocampal Cornu Ammonis 1 (CA1) regions was examined by Fluoro-Jade staining ex vivo, both hydrogen gas treatment regimens significantly improved spatial learning function and…
Read ArticleIn mice, hydrogen inhalation significantly reduced infarct volume, attenuated brain edema and improved neurobehavioral deficit in MCAO mice. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential…
Read ArticleIn 5 patients, lPO slightly increased at 3 h after the initiation of H₂ gas inhalation but was then maintained over 24 h. These findings add human evidence…
Read ArticleIn a laboratory model, hydrogen treatment diminished phosphorylation of Lyn kinase and release of tryptase, decreased accumulation and degranulation of mast cells, attenuated blood-brain barrier disruption, and improved…
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