Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In a laboratory model, all of the results indicated that hydrogen decreased the levels of reactive oxygen species, 8‑iso‑prostaglandin F2α and malondialdehyde, and promoted the UVB exposure‑induced expression of PI3K, Akt, Nrf2 and heme oxygenase‑1 in HaCaT cells. These findings from a…
Read ArticleIn male Sprague Dawley rats, preconditioning with one-time inhaled hydrogen does not attenuate skin flap IR injuries in rat models. These preclinical findings add evidence about the molecular-hydrogen…
Read ArticleIn a laboratory model, detected attenuation of DNA damage in the hydrogen exposure group as indirect evidence that intermittent exposure to hydrogen gas reduced oxidative stress. The authors…
Read ArticleIn male Sprague-Dawley rats, rIP1, RIP3, MLKL, PGAM5 and Drp1 were expressed at high levels in the IR group, and their expression was significantly decreased in the HCH…
Read ArticleIn mice, hydrogen treatment upregulated SIRT1 expression and promoted PINK1/Parkin-mediated mitophagy, leading to reduced phosphorylation of STING, decreased levels of pro-inflammatory cytokines (IL-1β, IL-6, and TNF-α), and suppressed…
Read ArticleThe second hypothesis is that H₂ treatment decreases sepsis-induced neuroinflammation in the hippocampus and prefrontal cortex, important areas related to short and long-term memory processing. This source-grounded publication…
Read ArticleThis narrative review examined the findings of recent studies on the use of hydrogen in emergency and critical care medicine using different disease models. Hydrogen is a new…
Read ArticleIn mice, molecular hydrogen treatment improved gut microbiota dysbiosis and partially amended metabolic disorder after SAE. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the…
Read ArticleIn mice, the load of blood and peritoneal lavage bacteria was increased, and H₂ treatment can significantly reduce it. These preclinical findings add evidence supporting molecular hydrogen's therapeutic…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. It has been reported that hydrogen gas exerts a therapeutic effect in a wide range of disease conditions, from acute…
Read ArticleIn 12 patients with confirmed SARS-CoV-2 infection, every patient showed clinical improvement and excellent tolerance to H₂ therapy. These findings add human evidence that helps define the outcomes…
Read ArticleIn mice, similarly, there was no significant change in the total SHIRPA score, although hydrogen-treated mice exhibited significantly lower spontaneous locomotor activity (P 0.05 for all). These preclinical…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Emerging evidence has consistently demonstrated that molecular hydrogen is a promising therapeutic option for a variety of diseases and the…
Read ArticleIn 20 patients with advanced non-small cell lung cancer, 45 the researchers found that the prevalence of insomnia, dizziness and headache could be reduced significantly after H₂ inhalation,…
Read ArticleThe HC rapidly decreased to 10% of the plateau level in about 6 min and 18 min in arterial and venous blood, respectively after H₂ inhalation was discontinued.…
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