Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In mice, as a result, Apoa2 protein or mRNA was identified as a target biomarker for H₂ with a protective, causal relationship with sepsis. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in…
Read ArticleIn 6 patients with chronic obstructive pulmonary disease (COPD), however, no significant differences were observed in lung function, DLCO, sleep quality, and 6 MWT before and after hydrogen…
Read ArticleIn male C57BL/6 mice, hydrogen inhalation also significantly reduced inflammatory cytokine and chemokine mRNA levels and improved oxygenation. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential…
Read ArticleIn mice, hydrogen inhalation increased the survival rate to 80%, reduced LPS-induced lung damage, and decreased inflammatory cytokine release in LPS mice. These preclinical findings add evidence supporting…
Read ArticleThe results suggest that hydrogen inhalation inhibits the deterioration of respiratory physiological function and alveolar fibrosis in this model of lung injury. These preclinical findings add evidence supporting…
Read ArticleIn an animal model, hydrogen treatment during exposure to hyperoxia significantly improved blood oxygenation, reduced inflammatory events, and induced HO-1 expression. These preclinical findings add evidence supporting molecular…
Read ArticleIn mice, hydrogen gas did not alleviate LPS-induced liver injury under the conditions tested. These results are preclinical and suggest that molecular hydrogen did not improve the measured…
Read ArticleIn an animal model, sepsis-challenged animals had decreased survival rate, as well as had increased bacterial burden in blood, peritoneal lavage, and lung sample, which were significantly ameliorated…
Read ArticleIn mice, hydrogen gas inhalation increased NFκB DNA binding after 1h of ventilation and decreased NFκB DNA binding after 2h of ventilation, as compared with controls. These preclinical…
Read ArticleIn mice, these results demonstrate that molecular hydrogen treatment ameliorates LPS-induced ALI through reducing lung inflammation and apoptosis, which may be associated with the decreased NF-κB activity. These…
Read ArticleIn By using cecal ligation and puncture (CLP), a classic septic model, the researchers explored the role of 2% H₂ treatment in sepsis-induced acute lung injury (ALI) linked…
Read ArticleIn rats, hyperoxia exposure increased glutathione content in lung homogenate (36%) more than hyperoxia+H₂ (21%), consistent with increases measured in Tc-HMPAO lung uptake. These preclinical findings add evidence…
Read ArticleIn rats, exposure to 1.3% hydrogen significantly attenuated the upregulation of the messenger RNAs for several proinflammatory mediators induced by HS/R. Hydrogen inhalation did not affect hemodynamic status…
Read ArticleIn rats, hydrogen inhalation significantly reduced the number of inflammatory cells in the bronchoalveolar lavage fluid, and the mRNA and protein expression levels of tumor necrosis factor alpha,…
Read ArticleIn mice, hydrogen gas inhalation markedly upregulated the activity of decreased superoxide dismutase and significantly attenuated the increased level of malondialdehyde and myeloperoxidase. These preclinical findings add evidence…
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