Hydrogen inhalation ameliorates hepatic inflammation and modulates gut microbiota in rats with high-fat diet-induced non-alcoholic fatty liver disease.
This animal study examined Hydrogen inhalation ameliorates hepatic inflammation and modulates gut microbiota in rats with high-fat diet-induced non-alcoholic fatty liver disease. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation; reported duration 10 weeks. The abstract reports: Liver transcriptomic data suggested that H treatment significantly downregulated inflammatory response genes, and the lipopolysaccharide (LPS)/Toll-like receptor (TLR) 4/nuclear transcription factor kappa B (NF-κB)…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas alleviates acute alcohol-induced liver injury by inhibiting JNK activation.
This animal study examined Hydrogen gas alleviates acute alcohol-induced liver injury by inhibiting JNK activation. The abstract describes Mouse model; reported duration 4 days. The abstract reports: Therefore, the results of the present study demonstrated that treatment with exogenous H by intraperitoneal injection may alleviate acute alcohol-induced liver injury by inhibiting…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas inhalation attenuates sepsis-induced liver injury in a FUNDC1-dependent manner.
This animal study examined Hydrogen gas inhalation attenuates sepsis-induced liver injury in a FUNDC1-dependent manner. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: We have demonstrated that hydrogen gas (H), a selective antioxidant, exerts protective effects in septic mice. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAnti-inflammatory properties of molecular hydrogen: investigation on parasite-induced liver inflammation.
This animal study examined Anti-inflammatory properties of molecular hydrogen: investigation on parasite-induced liver inflammation. The abstract describes Mouse model. The abstract reports: It has been suggested therefore to use gaseous hydrogen in a new anti-inflammatory strategy. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAnti-oxidant and anti-inflammatory effects of hydrogen-rich water alleviate ethanol-induced fatty liver in mice.
This animal study examined Anti-oxidant and anti-inflammatory effects of hydrogen-rich water alleviate ethanol-induced fatty liver in mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: HRW protects against chronic EtOH-induced liver injury, possibly by inducing acyl ghrelin to suppress the pro-inflammatory cytokines TNF-α and IL-6 and induce IL-10 and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreLong-Term Consumption of Hydrogen-Rich Water Mitigates Oxidative Stress, Hepatic Inflammation, and Apoptosis in Rats with LPS-Induced Chronic Liver Injury.
This animal study examined Long-Term Consumption of Hydrogen-Rich Water Mitigates Oxidative Stress, Hepatic Inflammation, and Apoptosis in Rats with LPS-Induced Chronic Liver Injury. The abstract describes Rat model; hydrogen delivered as hydrogen water; reported duration 8 months. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas (H) delivered by intraperitoneal injection alleviated methionine- and choline-deficient diet-induced metabolic dysfunction-associated steatotic liver disease in mice via inhibiting GSDMD- and GSDME-mediated pyroptosis.
This animal study examined Hydrogen gas (H) delivered by intraperitoneal injection alleviated methionine- and choline-deficient diet-induced metabolic dysfunction-associated steatotic liver disease in mice via inhibiting GSDMD- and GSDME-mediated pyroptosis. The abstract describes Mouse model; hydrogen delivered as injected or infused hydrogen. The abstract reports: H is an anti-pyroptosis gas molecule, intraperitoneal injection of H is a novel therapeutic strategy for MASLD that deserves further investigation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas ameliorates acute alcoholic liver injury via anti-inflammatory and antioxidant effects and regulation of intestinal microbiota.
This animal study examined Hydrogen gas ameliorates acute alcoholic liver injury via anti-inflammatory and antioxidant effects and regulation of intestinal microbiota. The abstract describes Mouse model. The abstract reports: Hydrogen gas (H) has been demonstrated to be an efficient antioxidant in various diseases in animals as well as humans. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas alleviates acute ethanol-induced hepatotoxicity in mice via modulating TLR4/9 innate immune signaling and pyroptosis.
This animal study examined Hydrogen gas alleviates acute ethanol-induced hepatotoxicity in mice via modulating TLR4/9 innate immune signaling and pyroptosis. The abstract describes Mouse model. The abstract reports: Our results showed that intraperitoneal injection of H improved acute ethanol-induced liver injury in mice in a dose dependent manner, as indicated by decreasing…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water protects against liver injury in nonalcoholic steatohepatitis through HO-1 enhancement via IL-10 and Sirt 1 signaling.
This in vitro or cellular study examined Hydrogen-rich water protects against liver injury in nonalcoholic steatohepatitis through HO-1 enhancement via IL-10 and Sirt 1 signaling. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreRenal replacement strategies: dual benefits of hydrogen gas inhalation and hydrogen-enriched dialysate.
This uncontrolled human study examined Renal replacement strategies: dual benefits of hydrogen gas inhalation and hydrogen-enriched dialysate. The abstract describes Human participants; sample size 11; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: Emerging clinical evidence suggests that combining H2 gas inhalation and RRT using H2-enriched dialysate may enhance the management of oxidative stress and inflammation in…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular Hydrogen as a Potential Adjunctive Therapy to Improve Renal Function and Reduce Fatigue in an Elderly Patient With Chronic Comorbidities: A Case Report
This case report or case series examined Molecular Hydrogen as a Potential Adjunctive Therapy to Improve Renal Function and Reduce Fatigue in an Elderly Patient With Chronic Comorbidities: A Case Report. The abstract describes Human participants; reported duration 40 years. The abstract reports: Hydrogen therapy was associated with improved renal function and a reduced chronic fatigue in this elderly patient with multiple comorbidities, including CAD, DM, and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAerosol inhalation of a hydrogen-rich solution restored septic renal function.
This animal study examined Aerosol inhalation of a hydrogen-rich solution restored septic renal function. The abstract describes Mouse model; hydrogen delivered as injected or infused hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Saline Promotes the Recovery of Renal Function after Ischemia/Reperfusion Injury in Rats via Anti-apoptosis and Anti-inflammation.
This animal study examined Hydrogen-Rich Saline Promotes the Recovery of Renal Function after Ischemia/Reperfusion Injury in Rats via Anti-apoptosis and Anti-inflammation. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: HRSS showed a protective effect in the prevention of renal injury and could promote renal function recovery after I/R injury in rats. HRSS might…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of hydrogen-rich saline on early acute kidney injury in severely burned rats by suppressing oxidative stress induced apoptosis and inflammation.
This uncontrolled human study examined Effects of hydrogen-rich saline on early acute kidney injury in severely burned rats by suppressing oxidative stress induced apoptosis and inflammation. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline. The abstract reports: Hydrogen can attenuate severe burn-induced early AKI; the mechanisms of protection include the inhibition of oxidative stress induced apoptosis and inflammation, which may be…. This is an automated editorial draft based on the abstract and requires source review before publication.
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