Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
This meta analysis examined this study aimed to systematically evaluate the preclinical evidence on the therapeutic efficacy and underlying mechanisms of hydrogen-delivering biomaterial carriers in the treatment of diabetic foot ulcer (DFU). The analysis showed that the CD206 expression in the hydrogen-treated…
Read ArticleIn mice, H₂ pretreatment by intraperitoneal injection improved LPS-induced acute liver injury in mice as indicated by reducing inflammatory cells infiltration in the liver, down-regulating serum ALT and…
Read ArticleIn this animal study, the authors report that HRW treatment significantly attenuated disease severity by reducing disease activity index, preserving colon length, decreasing pro-inflammatory cytokines, and partially restoring…
Read ArticleIn mice, hydrogen-rich water improved the motor function of fatigue mice, reduced the levels of fatigue-related biomarkers (blood urea nitrogen, lactate, and creatine kinase), and alleviated gastrocnemius muscle…
Read ArticleThis narrative review examined recent progress in molecular H₂ research, spanning from fundamental mechanisms in cancer biology, the role in adjuvant therapy, to the development of innovative catalytic…
Read ArticleThis systematic review examined hydrogen (H₂ ) therapy demonstrates selective antioxidant and anti-inflammatory properties with potential therapeutic value for multiple forms of hearing loss, though consolidated evidence is…
Read ArticleThis narrative review examined nevertheless, this narrative review provides a novel theoretical framework integrating hydrogen with the mast cell‐sleep‐wake rhythm‐melatonin axis, identifies shared pathological targets (oxidative stress, mitochondrial…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
Read ArticleIn For immunophenotypic analysis, macrophages were gently detached with cold phosphate-buffered saline (PBS), pipetted into single cells, and then suspended at 1 × 10 6 cells/ml, the NF-κB…
Read ArticleIn a laboratory model, mechanistically, a sustained supply of hydrogen molecules induces anti-inflammatory M2 macrophage polarization in time by enhancing CCL2 (chemokine C-C motif ligand 2) expression to…
Read ArticleIn rats, through transmission electron microscopy, the researchers observed that the GSDMD membrane pores in AMs were increased at 12 and 24 h post-burn compared with sham rats;…
Read ArticleThe researchers observed that anxiety/depression-like behaviors in experimental autoimmune encephalomyelitis (EAE) mice were alleviated by MgH2 treatment. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within…
Read ArticleERW treatment induced apoptosis of breast cancer cell lines independently of the status of p53 and ER and PR receptors, electrochemical reduced water (ERW) has been proposed to…
Read ArticleIn an animal model, regarding the neurological score, the piglets in the TH-H₂ group consistently had the highest score from day 2 to 5 and showed a significantly…
Read ArticleIn an animal model, the released hydrogen gas can effectively regulate redox homeostasis and mitigate excessive inflammation, and the silicic acid can promote the proliferation of reparative cells…
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