Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
H₂ may be superior to conventional antioxidants, since it can selectively reduce ●OH radicals while preserving important ROS that are otherwise used for normal cellular signaling. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained in a transparent general…
Read ArticleIn an animal model, focused on the mechanism and role of autophagy and inflammasome, by which hydrogen alleviated the hyperpathia induced by neuropathic pain. These preclinical findings add…
Read ArticleNanocarrier-mediated H₂ delivery, as well as in situ production of H₂ by nanogenerators, can significantly improve targeted accumulation of the gas and accelerate the therapeutic effects. This source-grounded…
Read ArticleSeven healthy adults were studied after they consumed hydrogen-rich water. Breath hydrogen increased rapidly and was near baseline within about an hour. The researchers reported that much of…
Read ArticleIn 14 healthy participants, ln SDNN was significantly increased after HRW administration when compared to placebo in 45 min (HRW: 4.41 ± 0.42 ms, placebo: 4.28 ± 0.31…
Read ArticleHowever, the researchers showed previously that inhalation of H₂ markedly suppresses brain injury induced by focal ischemia-reperfusion by buffering oxidative stress. This source-grounded publication contributes evidence relevant to…
Read ArticleIn participants, drinking-pause for 4 weeks after drinking hydrogen-water, however, saliva ORP, gradually but not instantly, increased to +60 to +80 mV, but upon drinking-resumption and 2 weeks…
Read ArticleThis narrative review examined the biological rationale and early clinical evidence for oxy-hydrogen inhalation in respiratory conditions. The authors highlighted early evidence of cytoprotective, antioxidant, and anti-inflammatory effects.…
Read ArticleThis publication examined hydrogen gas using the study design reported by the authoritative source. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained in a…
Read ArticleHowever, most of the reported H₂ delivery systems for wound healing, including hydrogen gas, hydrogen-rich water, and hydrogen-rich saline, are very short-lived for the low solubility of hydrogen…
Read ArticleIn 8 patients (33 men and 16 women) with MetSyn [ 154 ], they found that H₂ treatment reduced levels of oxidation damage, increased activities of antioxidant enzymes,…
Read ArticleIn participants, after treatment with HRW, the IL-1β level of the HRW group decreased significantly (SMD =–0.73; 95% CI: –1.29 to –0.18; P=0.009; see Figure 3A ). These…
Read ArticleIn rats, molecular hydrogen can easily attach to biomembranes and enter cytosol, mitochondria and other organelles of the cell and convert the formed OH- to H₂O to prevent…
Read ArticleIn participants with cervical cancer undergoing CCRT were prospectively enrolled and randomized into an experimental group (n = 28) or a cont, no significant difference in tumor response…
Read ArticleThey found fewer graft-infiltrating T cells in allografts obtained from hydrogen water-treated recipients compared to those obtained from regular water-treated controls. This source-grounded publication contributes evidence relevant to…
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