Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
This narrative review examined the available molecular-hydrogen literature. preclinical studies demonstrate promising results, clinical trials conducted thus far have yielded mixed outcomes, with some trials reporting limited or no therapeutic benefit. Nonetheless, the surgical indications for DBS are relatively stringent, applying only…
Read ArticleIn an animal model, H₂ inhalation reduced activated microglia in the lesioned striatum, which is consistent with the observed reduced pro-inflammatory cytokines levels. These preclinical findings add evidence…
Read ArticleIn rats, hRS treatment had no significant effect on blood pressure, but it effectively attenuated left ventricular hypertrophy in SHR. These preclinical findings add evidence about the molecular-hydrogen…
Read ArticleIn mice, the relative expression level of caspase-3 protein in skin specimens of cGVHD mice increased to 7.17 on the 96th day after transplantation, significantly higher than 4.36…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. 27 Lastly, HS by intravitreal (20 μL of 400 mL saline solution with hydrogen greater than 0.6 mM) and intraperitoneal…
Read ArticleIn rats, hydrogen-rich saline (LH group) treatment significantly decreased the p38 MAPK mRNA expression and p-p38 MAPK protein levels compared with the L group (p < 0.05). These…
Read ArticleIn conclusion, oral administration of hydrogen-rich water or lactulose could both protect against the growth reduction and oxidative damage caused by Fusarium mycotoxins. These preclinical findings add evidence…
Read ArticleThis narrative review examined mAJOR. Since the researchers published the first paper in Nature Medicine, effects of hydrogen have been reported in more than 38 diseases, physiological states…
Read ArticleThis meta analysis examined the available molecular-hydrogen literature. For each method, hydrogen-modulated pathways were analysed by (i) the hypergeometric test (HGT) in the class of over-representation analysis (ORA),…
Read ArticleThis narrative review examined oxidative stress can play an important role in this situation, but antioxidant therapy to capture any excessive reactive oxygen species has not yet been…
Read ArticleIn rats, at 30 and 90 min, no significant difference among the experimental groups in the MAP or HR was observed, suggesting that the hydrogen-rich water had no…
Read ArticleIn 120 patients with CR were randomly divided into two groups, compared to saline irrigation, HRS nasal irrigation was found to improve CR clinical symptoms, especially in patients…
Read ArticleIn mice, a significant increase of t-PA and decrease of TGF-b1 and PAI-1 in the peritoneal fluids were observed in the hydrogen-rich saline-treated groups. hydrogen-rich saline did not…
Read ArticleIn Sprague-Dawley rats, hydrogen-rich saline treatment decreased the blood and placental MDA, proteinuria and the pro-inflammatory cytokine TNF-α, IL-1β in the placental tissues compared with those in L-NAME-treated…
Read ArticleIn mice, these findings suggest that molecular hydrogen attenuates HFHSD-induced metabolic disturbances primarily through suppression of adipose inflammation. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential…
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