Molecular hydrogen regulates PTEN‐AKT‐mTOR signaling via ROS to alleviate peritoneal dialysis‐related peritoneal fibrosis

This uncontrolled human study examined Molecular hydrogen regulates PTEN‐AKT‐mTOR signaling via ROS to alleviate peritoneal dialysis‐related peritoneal fibrosis. The abstract describes Human participants; hydrogen delivered as injected or infused hydrogen. The abstract reports: Furthermore, it has been found that molecular hydrogen alleviate fibrosis by eliminating intracellular ROS and inhibiting the activation of the PTEN/AKT/mTOR pathway. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich water inhibits glucose and α,β -dicarbonyl compound-induced reactive oxygen species production in the SHR.Cg-Leprcp/NDmcr rat kidney.

This uncontrolled human study examined Hydrogen-rich water inhibits glucose and α,β -dicarbonyl compound-induced reactive oxygen species production in the SHR.Cg-Leprcp/NDmcr rat kidney. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: These results indicate that HRW inhibits the production of α,β-dicarbonyl compounds and ROS in the kidneys of SHR.Cg-Leprcp/NDmcr rats. Therefore, it has therapeutic potential…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen alleviates nephrotoxicity induced by an anti-cancer drug cisplatin without compromising anti-tumor activity in mice.

This uncontrolled human study examined Molecular hydrogen alleviates nephrotoxicity induced by an anti-cancer drug cisplatin without compromising anti-tumor activity in mice. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: Hydrogen has potential for improving the quality of life of patients during chemotherapy by efficiently mitigating the side effects of cisplatin. This is an automated editorial draft based on the abstract and requires source review before publication.

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Consumption of hydrogen-rich water protects against ferric nitrilotriacetate-induced nephrotoxicity and early tumor promotional events in rats.

This animal study examined Consumption of hydrogen-rich water protects against ferric nitrilotriacetate-induced nephrotoxicity and early tumor promotional events in rats. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: We found that consumption with HW ameliorated Fe-NTA-induced renal injuries including suppressing elevation of serum creatinine and blood urea nitrogen and inhibited early tumor…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Consumption of hydrogen-rich water alleviates renal injury in spontaneous hypertensive rats.

This uncontrolled human study examined Consumption of hydrogen-rich water alleviates renal injury in spontaneous hypertensive rats. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: Recently, it has been demonstrated that hydrogen, as a novel antioxidant, can selectively reduce hydroxyl radicals and peroxynitrite anion to exert therapeutic antioxidant activity. This is an automated editorial draft based on the abstract and requires source review before publication.

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