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Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In rats, hRS reversed these changes, with the exception of HO-1 expression, which was increased further, and improved renal morphology. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.
Read ArticleIn an animal model, marginal kidney processed by hydrogen gas-containing preservation solution has been engrafted for long-term (longer than 100 days). These preclinical findings add evidence supporting molecular…
Read ArticleIn an animal model, after storage of the kidney in hydrogen-free preservation solution for 1 hour before transplantation, no urine production was observed and blood flow was not…
Read ArticleIn mice, aerosol inhalation of the HRS increased anti-inflammatory cytokine (Il-4 and Il-13) mRNA levels in renal tissues and promoted macrophage polarization to the M2 type, which generated…
Read ArticleIn an animal model, nineteen serum metabolites and 7 urine metabolites showed significant restoration to normal levels after hydrogen gas (H₂) treatment. These preclinical findings add evidence supporting…
Read ArticleIn male Sprague-Dawley rats, kEY FINDINGS: the researchers demonstrated that rats who inhale hydrogen gas showed improved renal function, alleviated pathological damage, oxidative stress and apoptosis in CIH…
Read ArticleIn rats, after I/R injury, BUN, Cr, Bcl-2, caspase-3, caspase-9, caspase-8, IL-6, and TNF-α were all significantly increased, while Bax expression was decreased. These preclinical findings add evidence…
Read ArticleIn contrast, treatment with HW improved allograft function, slowed the progression of CAN, reduced oxidant injury and inflammatory mediator production, and improved overall survival. These results are preclinical…
Read ArticleIn rats, it increased the level of IL-10 and SOD activity in renal tissues. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and…
Read ArticleIn Recent studies have indicated H₂ can be used as a novel antioxidant to protect cells,, hydrogen may attenuate CIH-induced renal injury at least partially via inhibiting renal…
Read ArticleIn rats, all these factors were significantly improved by both doses of HRS, but the mean histologic damage score, urea, Cr, CK, ROS, 8-OH-dG, GSH-PX, IL-6, and TNF-α…
Read ArticleIn male Sprague-Dawley rats, however, administration of HS significantly reduced the injury score. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological…
Read ArticleIn Sprague-Dawley rats, the oxidation-reduction potential and malondialdehyde levels were markedly reduced with HS treatment, whereas endogenous antioxidant enzyme activities were significantly increased. These preclinical findings add evidence…
Read ArticleIn male Sprague-Dawley rats, cytoprotective effects of the dual treatment in comparison with H₂ treatment and I-R renal injury were observed in terms of superoxide radical scavenging activity…
Read ArticleIn mice, the renal expressions of osteopontin (OPN), CD44, monocyte chemoattractant protein-1 (MCP-1) and interleukin-10 (IL-10) were markedly increased in glyoxylate-treated mice, and H₂ significantly attenuated the increase…
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