Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In an animal model, this study used a swine model of mildly hypothermic prolonged circulatory arrest and found that the addition of 2.4% inhaled hydrogen gas to inspiratory gases during and after the ischemic insult significantly decreased neurologic and renal injury compared…
Read ArticleThis in vitro or cellular study examined PGC-1α attenuates hydrogen peroxide-induced apoptotic cell death by upregulating Nrf-2 via GSK3β inactivation mediated by activated p38 in HK-2 Cells. The…
Read ArticleIn male Wistar rats, HRW treatment consistently reduced MDA levels and substantially restored catalase activity in the liver and testis (p < 0.05, p < 0.01). The combined…
Read ArticleIn mice, the H₂ concentration immediately increased in the liver but not in the kidney after drinking HW. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential…
Read ArticleIn male Sprague-Dawley rats, compared with the OLT group, HRS dramatically attenuated the histopathologic damage, restored the renal function, and decreased the oxidative stress level. These preclinical findings…
Read ArticleIn an animal model, hS significantly increased hydrogen concentration in liver and kidney tissues. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and…
Read ArticleIn 262 patients, the data indicates E-HD could have substantial clinical benefits beyond conventional HD therapy, and support the rationale to conduct clinical trials of H₂ application to…
Read ArticleHistological study revealed a significant increase in the number of mesothelial cells and a significant decrease in peritoneal thickness in the H₂-PD group as compared to the control…
Read ArticleIn 300 participants with correspondingly higher plasma ORP levels compared with control subjects, by investigating this novel approach, the researchers aim to contribute to the growing body of…
Read ArticleHemodialysis reduced the plasma ROS scavenging activity, as shown by the augmented reference H₂O₂ and HOCl counts (Rh2o2 and Rhocl, respectively) and decreased antioxidative activity (expressed as total…
Read ArticleIn rats, r(2)* values in the cortex were significantly decreased on Days 2, 4, and 7 compared with those on Day 0 in the GM group but not…
Read ArticleFollowing the introduction of hydrogen therapy, her renal function improved, evidenced by a reduction in serum creatinine levels.
Read ArticleIn male Sprague-Dawley rats, H₂-dissolved PD solutions could preserve mesothelial cells and peritoneal membrane integrity in PD rats. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Hydrogen is a simple, colorless, and biologically active small molecule gas that can react with reactive oxygen species. The reviewed…
Read ArticleIn an animal model, the total glomerular cell count was significantly higher in the HI group than in the other groups, with no difference between the HI-H₂ and…
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