Hydrogen-rich University of Wisconsin solution attenuates renal cold ischemia-reperfusion injury.

This in vitro or cellular study examined Hydrogen-rich University of Wisconsin solution attenuates renal cold ischemia-reperfusion injury. The abstract describes Epithelial cell model. The abstract reports: HRUW solution improved graft function and prolonged graft survival compared with simple cold storage using UW solution by protecting tubular epithelial cells from inflammation…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen Rich Water Attenuates Renal Injury and Fibrosis by Regulation Transforming Growth Factor-β Induced Sirt1.

This in vitro or cellular study examined Hydrogen Rich Water Attenuates Renal Injury and Fibrosis by Regulation Transforming Growth Factor-β Induced Sirt1. The abstract describes Epithelial cell model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-Rich Saline Alleviates Kidney Fibrosis Following AKI and Retains Klotho Expression.

This animal study examined Hydrogen-Rich Saline Alleviates Kidney Fibrosis Following AKI and Retains Klotho Expression. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline; reported duration 28 day. The abstract reports: Histological data showed that the HRS treatment significantly decreased the fibrosis in renal tissues when compared with the IR group, and both of BUN…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effect of a hydrogen (H2)-enriched solution on the albumin redox of hemodialysis patients.

This uncontrolled human study examined Effect of a hydrogen (H2)-enriched solution on the albumin redox of hemodialysis patients. The abstract describes Human participants. The abstract reports: However, the mean proportion of reversibly oxidized albumin in outlet serum was significantly lower than that in inlet serum following the H2-HD session, whereas…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Inhalation of Hydrogen Gas Is Beneficial for Preventing Contrast-Induced Acute Kidney Injury in Rats.

This animal study examined Inhalation of Hydrogen Gas Is Beneficial for Preventing Contrast-Induced Acute Kidney Injury in Rats. The abstract describes Rat model. The abstract reports: Results: One day after the injection, serum levels of urea nitrogen were significantly lower in H gas-inhaling CIAKI rats (17.6 ± 2.3 mg/dl) than…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Novel haemodialysis (HD) treatment employing molecular hydrogen (H)-enriched dialysis solution improves prognosis of chronic dialysis patients: A prospective observational study.

This observational study examined Novel haemodialysis (HD) treatment employing molecular hydrogen (H)-enriched dialysis solution improves prognosis of chronic dialysis patients: A prospective observational study. The abstract describes Human participants. The abstract reports: Multivariate analysis of the Cox proportional hazards model revealed E-HD as an independent significant factor for the primary endpoint (hazard ratio 0.59; [95% confidence…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen Gas Does Not Ameliorate Renal Ischemia Reperfusion Injury in a Preclinical Model.

This in vitro or cellular study examined Hydrogen Gas Does Not Ameliorate Renal Ischemia Reperfusion Injury in a Preclinical Model. The abstract describes Cell culture / in vitro model. This is an automated editorial draft based on the abstract and requires source review before publication.

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Inhalation of 4% and 67% hydrogen ameliorates oxidative stress, inflammation, apoptosis, and necroptosis in a rat model of glycerol-induced acute kidney injury

This animal study examined Inhalation of 4% and 67% hydrogen ameliorates oxidative stress, inflammation, apoptosis, and necroptosis in a rat model of glycerol-induced acute kidney injury. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen. The abstract reports: After 72 hours of glycerol injection (8 mL/kg), we found that glycerol triggered oxidative stress, inflammatory reactions, and apoptotic events. This is an automated editorial draft based on the abstract and requires source review before publication.

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Application of Electrolyzed Hydrogen Water for Management of Chronic Kidney Disease and Dialysis Treatment-Perspective View.

This uncontrolled human study examined Application of Electrolyzed Hydrogen Water for Management of Chronic Kidney Disease and Dialysis Treatment-Perspective View. The abstract describes Human participants; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

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Quantification of dissolved H and continuous monitoring of hydrogen-rich water for haemodialysis applications: An experimental study.

This uncontrolled human study examined Quantification of dissolved H and continuous monitoring of hydrogen-rich water for haemodialysis applications: An experimental study. The abstract describes Human participants; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

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Oral Hydrogen-Rich Water Alleviates Oxalate-Induced Kidney Injury by Suppressing Oxidative Stress, Inflammation, and Fibrosis.

This animal study examined Oral Hydrogen-Rich Water Alleviates Oxalate-Induced Kidney Injury by Suppressing Oxidative Stress, Inflammation, and Fibrosis. The abstract describes Mouse model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich water alleviates cyclosporine A-induced nephrotoxicity via the Keap1/Nrf2 signaling pathway.

This animal study examined Hydrogen-rich water alleviates cyclosporine A-induced nephrotoxicity via the Keap1/Nrf2 signaling pathway. The abstract describes Rat model; hydrogen delivered as hydrogen water; reported duration 4 weeks. The abstract reports: We found that CsA increased the levels of reactive oxygen species (ROS) and malonaldehyde (MDA), but it reduced glutathione (GSH) and superoxide dismutase (SOD)…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of hydrogen-rich water in a rat model of polycystic kidney disease

This observational study examined Effects of hydrogen-rich water in a rat model of polycystic kidney disease. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: This experiment showed that the effect of drinking large volumes of hydrogen-rich water was not significantly different from that of normal water, in terms…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen and kidney diseases: a scoping review based on scientometry and data analytics.

This systematic review examined Molecular hydrogen and kidney diseases: a scoping review based on scientometry and data analytics. The abstract describes Published literature review. The abstract reports: H₂ consistently demonstrated protective effects against apoptosis, fibrosis, inflammation, and oxidative stress across acute kidney injury, nephrotoxicity, transplantation, and early chronic kidney disease models. This is an automated editorial draft based on the abstract and requires source review before publication.

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Long-term administration of hydrogen-rich water enhances quality of life in diabetic rats and reduces renal neoplasm incidence through modulation of inflammatory and metabolic pathways.

This uncontrolled human study examined Long-term administration of hydrogen-rich water enhances quality of life in diabetic rats and reduces renal neoplasm incidence through modulation of inflammatory and metabolic pathways. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: This study advances the understanding of HRW's therapeutic mechanisms, particularly its ability to reprogram metabolic pathways. HRW shows promise as an alternative treatment for…. This is an automated editorial draft based on the abstract and requires source review before publication.

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