Intake of water with high levels of dissolved hydrogen (H2) suppresses ischemia-induced cardio-renal injury in Dahl salt-sensitive rats.

This animal study examined Intake of water with high levels of dissolved hydrogen (H2) suppresses ischemia-induced cardio-renal injury in Dahl salt-sensitive rats. The abstract describes Rat model. The abstract reports: Consumption of EW by ad libitum drinking has the potential to ameliorate ischemia-induced cardio-renal injury in CKD model rats. This indicates a novel strategy…. This is an automated editorial draft based on the abstract and requires source review before publication.

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[Influences of hydrogen-rich saline on acute kidney injury in severely burned rats and mechanism].

This animal study examined [Influences of hydrogen-rich saline on acute kidney injury in severely burned rats and mechanism]. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.

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Transperitoneal administration of dissolved hydrogen for peritoneal dialysis patients: a novel approach to suppress oxidative stress in the peritoneal cavity.

This uncontrolled human study examined Transperitoneal administration of dissolved hydrogen for peritoneal dialysis patients: a novel approach to suppress oxidative stress in the peritoneal cavity. The abstract describes Human participants. The abstract reports: Trans-peritoneal administration of H2 reduces peritoneal and systemic OS. This is an automated editorial draft based on the abstract and requires source review before publication.

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Mechanism of influence of molecular hydrogen on the function of the proximal tubule of the nephron in irritatable bowel syndrome | Journal of Education, Health and Sport

This uncontrolled human study examined Mechanism of influence of molecular hydrogen on the function of the proximal tubule of the nephron in irritatable bowel syndrome | Journal of Education, Health and Sport. The abstract describes Human participants; sample size 60; reported duration 7 days. The abstract reports: Statistical data processing was performed using computer programs "Statgrafics"and "Exel 7.0".Results and discussion. This is an automated editorial draft based on the abstract and requires source review before publication.

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Nephroprotective effect of electrolyzed reduced water against cisplatin-induced kidney toxicity and oxidative damage in mice.

This animal study examined Nephroprotective effect of electrolyzed reduced water against cisplatin-induced kidney toxicity and oxidative damage in mice. The abstract describes Mouse model; reported duration 28 days. The abstract reports: ERW exhibits potent nephroprotective effects on cisplatin-induced kidney damage in mice, likely due to both the increase in antioxidant-defense system activity and the inhibition…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effects of hydrogen-rich water against acute lead-induced hepatic, renal, and testicular toxicity in rats

This animal study examined Protective effects of hydrogen-rich water against acute lead-induced hepatic, renal, and testicular toxicity in rats. The abstract describes Rat model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-Rich Saline Attenuates Acute Kidney Injury After Liver Transplantation via Activating p53-Mediated Autophagy.

This animal study examined Hydrogen-Rich Saline Attenuates Acute Kidney Injury After Liver Transplantation via Activating p53-Mediated Autophagy. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: HRS is able to protect against AKI after liver transplantation partly by reducing apoptosis, which is possibly involved in the modulation of p53-mediated autophagy. This is an automated editorial draft based on the abstract and requires source review before publication.

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Possible clinical effects of molecular hydrogen (H2) delivery during hemodialysis in chronic dialysis patients: Interim analysis in a 12 month observation

This observational study examined Possible clinical effects of molecular hydrogen (H2) delivery during hemodialysis in chronic dialysis patients: Interim analysis in a 12 month observation. The abstract describes Human participants. The abstract reports: The data indicates E-HD could have substantial clinical benefits beyond conventional HD therapy, and support the rationale to conduct clinical trials of H2 application…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Translational Research of Peritoneal Dialysis Solution with Dissolved Molecular Hydrogen.

This uncontrolled human study examined Translational Research of Peritoneal Dialysis Solution with Dissolved Molecular Hydrogen. The abstract describes Human participants; reported duration 3 weeks. The abstract reports: Also, results of immunostaining analysis revealed increased vimentin and apoptotic cells in the membrane of the PD group, indicating that H2 may play a…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Renal replacement strategies: dual benefits of hydrogen gas inhalation and hydrogen-enriched dialysate.

This uncontrolled human study examined Renal replacement strategies: dual benefits of hydrogen gas inhalation and hydrogen-enriched dialysate. The abstract describes Human participants; sample size 11; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: Emerging clinical evidence suggests that combining H2 gas inhalation and RRT using H2-enriched dialysate may enhance the management of oxidative stress and inflammation in…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effect of hydrogen-rich water against gentamicin-induced nephrotoxicity in rats using blood oxygenation level-dependent MR imaging.

This animal study examined Protective effect of hydrogen-rich water against gentamicin-induced nephrotoxicity in rats using blood oxygenation level-dependent MR imaging. The abstract describes Rat model; hydrogen delivered as hydrogen water and injected or infused hydrogen; reported duration 7 days. The abstract reports: Our findings suggested reduced oxygen utility, mainly in the cortex, in gentamicin-induced nephrotoxicity and an ameliorative effect of hydrogen-rich water against GIN. This is an automated editorial draft based on the abstract and requires source review before publication.

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Reduced hemodialysis-induced oxidative stress in end-stage renal disease patients by electrolyzed reduced water.

This uncontrolled human study examined Reduced hemodialysis-induced oxidative stress in end-stage renal disease patients by electrolyzed reduced water. The abstract describes Human participants; reported duration 1 month. The abstract reports: This study demonstrates that hemodialysis with ERW administration may efficiently increase the H2O2- and HOCl-dependent antioxidant defense and reduce H2O2- and HOCl-induced oxidative stress. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular Hydrogen as a Potential Adjunctive Therapy to Improve Renal Function and Reduce Fatigue in an Elderly Patient With Chronic Comorbidities: A Case Report

This case report or case series examined Molecular Hydrogen as a Potential Adjunctive Therapy to Improve Renal Function and Reduce Fatigue in an Elderly Patient With Chronic Comorbidities: A Case Report. The abstract describes Human participants; reported duration 40 years. The abstract reports: Hydrogen therapy was associated with improved renal function and a reduced chronic fatigue in this elderly patient with multiple comorbidities, including CAD, DM, and…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Dissolved molecular hydrogen (H) in Peritoneal Dialysis (PD) solutions preserves mesothelial cells and peritoneal membrane integrity.

This uncontrolled human study examined Dissolved molecular hydrogen (H) in Peritoneal Dialysis (PD) solutions preserves mesothelial cells and peritoneal membrane integrity. The abstract describes Human participants. The abstract reports: H-dissolved PD solutions could preserve mesothelial cells and peritoneal membrane integrity in PD rats. Clinical application of H in PD could be a novel…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Therapeutic effect of hydrogen and its mechanisms in kidney disease treatment.

This narrative review examined Therapeutic effect of hydrogen and its mechanisms in kidney disease treatment. The abstract describes Published literature review. The abstract reports: Recent research suggests that hydrogen possesses several biological effects, including antioxidant, anti-inflammatory, and anti-apoptotic effects, while exhibiting an extremely high level of safety. This is an automated editorial draft based on the abstract and requires source review before publication.

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