Molecular hydrogen is a novel antioxidant to efficiently reduce oxidative stress with potential for the improvement of mitochondrial diseases.
This narrative review examined Molecular hydrogen is a novel antioxidant to efficiently reduce oxidative stress with potential for the improvement of mitochondrial diseases. The abstract describes Published literature review; hydrogen delivered as hydrogen water and hydrogen bath. The abstract reports: Hydrogen has biological benefits toward preventive and therapeutic applications; however, the molecular mechanisms underlying the marked effects of small amounts of hydrogen remain elusive. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich jelly attenuates adipose tissue inflammation and metabolic dysfunction in high-fat/high-sucrose diet-fed SAMP8 mice.
This in vitro or cellular study examined Hydrogen-rich jelly attenuates adipose tissue inflammation and metabolic dysfunction in high-fat/high-sucrose diet-fed SAMP8 mice. The abstract describes Cell culture / in vitro model. The abstract reports: These findings suggest that molecular hydrogen attenuates HFHSD-induced metabolic disturbances primarily through suppression of adipose inflammation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular Hydrogen Promotes Adipose-derived Stem Cell Myogenic Differentiation Regulation of Mitochondria.
This in vitro or cellular study examined Molecular Hydrogen Promotes Adipose-derived Stem Cell Myogenic Differentiation Regulation of Mitochondria. The abstract describes Stem-cell model. The abstract reports: This study reveals the application potential of H in skeletal muscle diseases or other pathologies related to mitochondrial dysfunction. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen affects body composition, metabolic profiles, and mitochondrial function in middle-aged overweight women.
This registered clinical trial examined Molecular hydrogen affects body composition, metabolic profiles, and mitochondrial function in middle-aged overweight women. The abstract describes Planned or registered research population; reported duration 4 week. The abstract reports: It appears that orally administered H as a blend of hydrogen-generating minerals might be a beneficial agent in the management of body composition and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreRole of molecular hydrogen in obesity treatment: modulation of GLP-1, irisin, and PGC-1α for improved metabolism.
This meta-analysis examined Role of molecular hydrogen in obesity treatment: modulation of GLP-1, irisin, and PGC-1α for improved metabolism. The abstract describes Published literature review; sample size 1088; hydrogen delivered as hydrogen water and hydrogen inhalation. The abstract reports: Dihydrogen is a medical gas with extensively documented antioxidant, anti-inflammatory, and signaling properties, validated in over 1000 studies across more than 100 disease models,1…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreDGKζ in Glycerophospholipid Metabolism Regulates the DAG and PA Balance and Interacts With PTEN to Alleviate Brain Damage in Septic Mice With Hydrogen Inhalation: A Comparative Metabolomic and Phosphoproteomic Analysis.
This narrative review examined DGKζ in Glycerophospholipid Metabolism Regulates the DAG and PA Balance and Interacts With PTEN to Alleviate Brain Damage in Septic Mice With Hydrogen Inhalation: A Comparative Metabolomic and Phosphoproteomic Analysis. The abstract describes Published literature review; hydrogen delivered as hydrogen inhalation. The abstract reports: The correlated differential phosphoproteins found in the combined metabolomic and phosphoproteomic analyses participated in 131 pathways, and the differentially abundant metabolites were involved in…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water and caffeine for alertness and brain metabolism in sleep-deprived habitual coffee drinkers.
This randomized controlled trial examined Hydrogen-rich water and caffeine for alertness and brain metabolism in sleep-deprived habitual coffee drinkers. The abstract describes Human participants; hydrogen delivered as hydrogen water; reported duration 15 min. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of hydrogen‑rich saline against experimental diabetic peripheral neuropathy via activation of the mitochondrial ATP‑sensitive potassium channel channels in rats.
This animal study examined Protective effects of hydrogen‑rich saline against experimental diabetic peripheral neuropathy via activation of the mitochondrial ATP‑sensitive potassium channel channels in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: It has previously been demonstrated that hyperglycemia‑induced oxidative stress and inflammation are closely associated with the development of diabetic complications, including diabetic neuropathy. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of hydrogen-rich saline in neuroinflammation and mitochondrial dysfunction in rat model of sepsis-associated encephalopathy.
This uncontrolled human study examined Effects of hydrogen-rich saline in neuroinflammation and mitochondrial dysfunction in rat model of sepsis-associated encephalopathy. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: These data demonstrated that HRS can improve survival rate, attenuate neuroinflammation, astrocyte and microglial activation, neuronal injury and mitochondrial dysfunction in juvenile SAE rat…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Gas Alleviates Sepsis-Induced Brain Injury by Improving Mitochondrial Biogenesis Through the Activation of PGC-α in Mice.
This uncontrolled human study examined Hydrogen Gas Alleviates Sepsis-Induced Brain Injury by Improving Mitochondrial Biogenesis Through the Activation of PGC-α in Mice. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: The present study showed that hydrogen gas therapy increased the 7-day survival rate, improved cognitive function, increased the mitochondrial function (MMP, ATP level, complex…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreDirect Targets and Subsequent Pathways for Molecular Hydrogen to Exert Multiple Functions: Focusing on Interventions in Radical Reactions
This narrative review examined Direct Targets and Subsequent Pathways for Molecular Hydrogen to Exert Multiple Functions: Focusing on Interventions in Radical Reactions | Bentham Science. The abstract describes Published literature review. The abstract reports: The resulting suppression of Ca2+-signaling inactivates multiple functional NFAT and CREB transcription factors, which may explain H multi-functionality. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreA link between gut community metabolism and pathogenesis: molecular hydrogen-stimulated glucarate catabolism aids Salmonella virulence.
This animal study examined A link between gut community metabolism and pathogenesis: molecular hydrogen-stimulated glucarate catabolism aids Salmonella virulence. The abstract describes Mouse model. The abstract reports: Our results link a gut microbiome-produced diffusible metabolite to augmenting bacterial pathogenesis. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreTaurine, Coenzyme Q10, and Hydrogen Water Prevents Germanium Dioxide-Induced Mitochondrial Dysfunction and Associated Sensorineural Hearing Loss in mouse
This animal study examined Taurine, Coenzyme Q10, and Hydrogen Water Prevents Germanium Dioxide-Induced Mitochondrial Dysfunction and Associated Sensorineural Hearing Loss in mouse. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: In the current study, we showed that supplementation with germanium dioxide (GeO) in CBA/J mice resulted in SNHL due to the degeneration of the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen stimulates the gene expression of transcriptional coactivator PGC-1α to enhance fatty acid metabolism.
This animal study examined Molecular hydrogen stimulates the gene expression of transcriptional coactivator PGC-1α to enhance fatty acid metabolism. The abstract describes Mouse model. The abstract reports: The expression of might be regulated indirectly through sequential regulation by H, 4-hydroxy-2-nonenal, and Akt/FoxO1 signaling, as suggested in cultured cell experiments. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline attenuates neuronal ischemia–reperfusion injury by protecting mitochondrial function in rats.
This animal study examined Hydrogen-rich saline attenuates neuronal ischemia–reperfusion injury by protecting mitochondrial function in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Hydrogen, a popular antioxidant gas, can selectively reduce cytotoxic oxygen radicals and has been found to protect against ischemia-reperfusion (I/R) injury of multiple organs. This is an automated editorial draft based on the abstract and requires source review before publication.
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