Mitochondria: one of the vital hubs for molecular hydrogen’s biological functions.
This narrative review examined Mitochondria: one of the vital hubs for molecular hydrogen’s biological functions. The abstract describes Published literature review. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline protects against mitochondrial dysfunction and apoptosis in mice with obstructive jaundice.
This animal study examined Hydrogen-rich saline protects against mitochondrial dysfunction and apoptosis in mice with obstructive jaundice. The abstract describes Mouse model; sample size 6; hydrogen delivered as hydrogen-rich saline. The abstract reports: Previous studies have demonstrated that hydrogen-rich saline (HS) protects against bile duct ligation (BDL)-induced liver injury by suppressing oxidative stress and inflammation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Activates ATP-Binding Cassette Transporter A1-Dependent Efflux Ex Vivo and Improves High-Density Lipoprotein Function in Patients With Hypercholesterolemia: A Double-Blinded, Randomized, and Placebo-Controlled Trial
This randomized controlled trial examined Hydrogen Activates ATP-Binding Cassette Transporter A1-Dependent Efflux Ex Vivo and Improves High-Density Lipoprotein Function in Patients With Hypercholesterolemia: A Double-Blinded, Randomized, and Placebo-Controlled Trial. The abstract describes Human participants; sample size 34; reported duration 10 weeks. The abstract reports: H2 activates ATP-binding cassette transporter A1-dependent efflux, enhances HDL antiatherosclerotic functions, and has beneficial lipid-lowering effects. The present findings highlight the potential role of…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen suppresses superoxide generation in the mitochondrial complex I and reduced mitochondrial membrane potential.
This in vitro or cellular study examined Molecular hydrogen suppresses superoxide generation in the mitochondrial complex I and reduced mitochondrial membrane potential. The abstract describes Cell culture / in vitro model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen modulates gene expression via histone modification and induces the mitochondrial unfolded protein response.
This animal study examined Molecular hydrogen modulates gene expression via histone modification and induces the mitochondrial unfolded protein response. The abstract describes Mouse model. The abstract reports: We found that H activated the expression of sets of genes regulated by histone H3K27 methylation status. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen restores central tryptophan and metabolite levels and maintains mitochondrial homeostasis to protect rats from chronic mild unpredictable stress damage.
This animal study examined Hydrogen restores central tryptophan and metabolite levels and maintains mitochondrial homeostasis to protect rats from chronic mild unpredictable stress damage. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: The results collectively indicated that hydrogen significantly attenuated CUMS-induced depressive-like behavior and monoamine neurotransmitter deficiency, as well as protected the brain from oxidative stress…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen inhalation modulates resting metabolism in healthy females: findings from a randomized, double-blind, placebo-controlled crossover study.
This randomized controlled trial examined Molecular hydrogen inhalation modulates resting metabolism in healthy females: findings from a randomized, double-blind, placebo-controlled crossover study. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation; reported duration 60 minutes. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water supplementation improves metabolic profile during peripartum period in Gurcu goats and enhances the health and survival of kids.
This animal study examined Hydrogen-rich water supplementation improves metabolic profile during peripartum period in Gurcu goats and enhances the health and survival of kids. The abstract describes hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreTherapeutic Potential of Molecular Hydrogen in Metabolic Diseases from Bench to Bedside.
This narrative review examined Therapeutic Potential of Molecular Hydrogen in Metabolic Diseases from Bench to Bedside. The abstract describes Published literature review. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe Effect of Adjuvant Therapy with Molecular Hydrogen on Endogenous Coenzyme Q Levels and Platelet Mitochondrial Bioenergetics in Patients with Non-Alcoholic Fatty Liver Disease.
This uncontrolled human study examined The Effect of Adjuvant Therapy with Molecular Hydrogen on Endogenous Coenzyme Q Levels and Platelet Mitochondrial Bioenergetics in Patients with Non-Alcoholic Fatty Liver Disease. The abstract describes Human participants; sample size 30; hydrogen delivered as hydrogen water; reported duration 8 weeks. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreNanocapsule-mediated sustained H release in the gut ameliorates metabolic dysfunction-associated fatty liver disease.
This uncontrolled human study examined Nanocapsule-mediated sustained H release in the gut ameliorates metabolic dysfunction-associated fatty liver disease. The abstract describes Human participants. The abstract reports: Moreover, hepatic transcriptome showed a reprogramed liver metabolism profile with reduced lipid synthesis and increased fatty acid metabolism. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreElectrolyzed Hydrogen Water Protects against Ethanol-Induced Cytotoxicity by Regulating Aldehyde Metabolism-Associated Enzymes in the Hepatic Cell Line HepG2.
This in vitro or cellular study examined Electrolyzed Hydrogen Water Protects against Ethanol-Induced Cytotoxicity by Regulating Aldehyde Metabolism-Associated Enzymes in the Hepatic Cell Line HepG2. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen water. The abstract reports: In this study, we found that EHW inhibits ethanol-induced cytotoxicity by decreasing the intracellular acetaldehyde, a toxic substance produced by ethanol degradation, in hepatocyte…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreLong-term consumption of hydrogen-rich water provides hepatoprotection by improving mitochondrial biology and quality control in chronically stressed mice.
This animal study examined Long-term consumption of hydrogen-rich water provides hepatoprotection by improving mitochondrial biology and quality control in chronically stressed mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: This study reveals that long-term hydrogen-rich water (HRW) consumption provides significant hepatoprotection in mice under chronic stress. HRW normalizes liver enzyme levels, enhances antioxidant…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas (H) delivered by intraperitoneal injection alleviated methionine- and choline-deficient diet-induced metabolic dysfunction-associated steatotic liver disease in mice via inhibiting GSDMD- and GSDME-mediated pyroptosis.
This animal study examined Hydrogen gas (H) delivered by intraperitoneal injection alleviated methionine- and choline-deficient diet-induced metabolic dysfunction-associated steatotic liver disease in mice via inhibiting GSDMD- and GSDME-mediated pyroptosis. The abstract describes Mouse model; hydrogen delivered as injected or infused hydrogen. The abstract reports: H is an anti-pyroptosis gas molecule, intraperitoneal injection of H is a novel therapeutic strategy for MASLD that deserves further investigation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreLong-term and daily use of molecular hydrogen induces reprogramming of liver metabolism in rats by modulating NADP/NADPH redox pathways.
This animal study examined Long-term and daily use of molecular hydrogen induces reprogramming of liver metabolism in rats by modulating NADP/NADPH redox pathways. The abstract describes Rat model. The abstract reports: Rats exposed 2 h daily to H either by drinking HRW (H dissolved in HO) or by breathing 4% H gas showed reduced lipogenesis and…. This is an automated editorial draft based on the abstract and requires source review before publication.
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