Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In This reaction disrupts mitochondrial function in cancer cells, reduces oxygen consumption, alleviates tumor hypoxia, and consequently counteracts chemoresistance, simultaneously, EPI induces immunogenic cell death (ICD) in moribund tumor cells, activating the host's antitumor immune response. These findings from a laboratory model…
Read ArticleIn The released H₂ disrupts the redox homeostasis and mitochondrial membrane integrity of tumor cells, synergizing with SDT, hydrogen can disrupt the intracellular redox balance and impair the…
Read ArticleIn This dual-path ROS generation mechanism sustains prolonged intracellular ROS burst to efficiently kill tumor cells, at the cellular level, when 4T1 cells pre‐stained with MB were treated…
Read ArticleIn an animal model, molecular hydrogen in hydrogen-rich liquid or inhaling gas, which has been confirmed in scavenging reactive oxygen species and preventing mitochondrial decay, improved metabolic syndrome…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Such abnormalities include extensive data showing that at least a subgroup has a pro-inflammatory state, increased oxidative and nitrosative stress,…
Read ArticleIn all three measurements, at 1-week, 1-month and 5-month time-point, respectively, the researchers observed that high dose of L-arabinose gavage could immediately elicit a dramatic increase of hydrogen…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Recent studies have reported that ROS activate NLRP3 inflammasomes, and that this stimulation triggers the production of proinflammatory cytokines. The…
Read ArticleIn a laboratory model, given the antioxidative effect of molecular hydrogen, some recent studies suggest the potential use of molecular hydrogen as a biomedicine for the treatment of…
Read ArticleIn Simulation of experimental tissue hypoxia was performed by a single intraperitoneal administration of 2,4-dinitrophenol at a dose of 3 mg/kg body weight [ 2 ], oMP c…
Read ArticleIn Thus, the researchers sought to examine the effects of short exposure to H₂ on lipid composition and associated physiological changes in SH-SY5Y neuroblastoma cells, metabolomic analysis also…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Important metabolic variables that lead to the development of many diseases, including "mitochondrial diseases," include increased oxidative stress and mitochondrial…
Read ArticleIn rats, the hydrogen concentration in the heart, liver, and spleen showed an increasing trend over time, and all exhibited a significant increase in hydrogen concentration at 5…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. H₂ is capable of capturing harmful •OH and ONOO- while maintaining the crucial reactive oxygen species (ROS) involved in cellular…
Read ArticleThis laboratory study evaluated the biological effects of molecular hydrogen. These findings come from a laboratory model and suggest molecular hydrogen's biological potential. Further research is needed to…
Read ArticleIn Hydrogen disrupts the mitochondrial function of cancer cells, interferes with their energy metabolism, and ultimately leads to energy depletion and apoptosis, by simultaneously generating hydrogen and oxygen…
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