Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In 30 patients with NAFLD and 15 healthy volunteers were included in this clinical trial, after 8 weeks of adjuvant therapy with HRW, the concentration of CoQ10 in platelets increased, plasma TBARS decreased, and the efficiency of OXPHOS improved, while in the…
Read ArticleIn rats, hydrogen gas reduced hepatic reperfusion injury after prolonged cold preservation via the maintenance of portal flow, by protecting mitochondrial function during the early phase of reperfusion,…
Read ArticleIn rats, saturated hydrogen saline also decreased phosphorylated extracellular signal-regulated kinase (p-ERK), phosphorylated Jun kinase (p-JNK), nuclear factor-kappa B (NF-kappaB), and second mitochondria-derived activator of caspase (Smac) levels,…
Read ArticleIn mice, HRW decreased Cytc, Bax, Caspase-3, and Caspase-8 levels, and increasing the expression of Bcl-2. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the…
Read ArticleIn Sprague-Dawley rats, long-term HRW consumption significantly reduced LPS-induced inflammatory cell infiltration in liver tissue, suppressed the abnormal elevation of pro-inflammatory factors, and maintained relatively stable expression levels…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. The infection induces pathological responses including increased inflammation, oxidative stress, and apoptosis. The reviewed evidence adds support for molecular hydrogen's…
Read ArticleIn mice, hydrogen-rich water has been suggested to exert a general antioxidant effect in relation to both improving lifestyle and preventing a series of diseases. These preclinical findings…
Read ArticleIn This study utilized next-generation sequencing (NGS) to assess mRNA and miRNA expression in EHW-treated Caco-2 cells, eHW treatment significantly decreased the levels of miR-429 and miR-200c-3p and…
Read ArticleIn rats, HRW treatment effectively alleviated the degenerative changes in the retinal outer nuclear layer, improved retinal function, and reduced retinal inflammation in treated rats. These preclinical findings…
Read ArticleIn rats, s-nitroso-N-acetylpenicillamine treatment decreased the cell numbers in the ganglion cell layer and inner nuclear layer, but the presence of H₂ inhibited this reduction. These preclinical findings…
Read ArticleIn rats, the pre-exercise supplement of vitamin C significantly reduced mitochondrial complex IV concentrations and PGC-1α, NRF-1, TFAM gene expression levels compared to the pre-exercise group, but the…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Disease and noxious forms of exercise promote redox dysregulation and chronic inflammation, changes that are mitigated by H₂ administration. The…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
Read ArticleIn rats, similarly, coenzyme Q9 levels in the rat plasma, myocardial tissue, and mitochondria were increased and malondialdehyde level in plasma was reduced after HRW administration. These preclinical…
Read ArticleIn rats, compared with MP, MP-H₂ treatment reduced lysophosphatidylinositol (LPI) levels and the LPI/phosphatidylinositol ratio while increasing phosphatidic acid (PA) species such as PA (18:0/18:1) and PA (18:0/20:4).…
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