Molecular Hydrogen Effectively Heals Alkali-Injured Cornea via Suppression of Oxidative Stress.
This animal study examined Molecular Hydrogen Effectively Heals Alkali-Injured Cornea via Suppression of Oxidative Stress. The abstract describes Rabbit model. The abstract reports: Results show that irrigation of the damaged eyes with H solution immediately after the injury and then within next five days renewed corneal transparency…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePreventive and therapeutic application of molecular hydrogen in situations with excessive production of free radicals.
This narrative review examined Preventive and therapeutic application of molecular hydrogen in situations with excessive production of free radicals. The abstract describes Published literature review. The abstract reports: There is a growing body of evidence based on the results of animal experiments and clinical observations that H(2) may represent an effective antioxidant…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas alleviates blood-brain barrier impairment and cognitive dysfunction of septic mice in an Nrf2-dependent pathway
This animal study examined Hydrogen gas alleviates blood-brain barrier impairment and cognitive dysfunction of septic mice in an Nrf2-dependent pathway. The abstract describes Mouse model. The abstract reports: We found that H can improve survival in septic mice, decrease escape latency and platform crossing times, decrease pro-inflammatory cytokines and oxidative product levels…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreRedox-Mechanisms of Molecular Hydrogen Promote Healthful Longevity.
This narrative review examined Redox-Mechanisms of Molecular Hydrogen Promote Healthful Longevity. The abstract describes Published literature review. The abstract reports: Excessive levels of both pro- and anti-oxidant species qualify as oxidative stress (OS) and result in damage to molecules and cells. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreA new insight into the molecular hydrogen effect on coenzyme Q and mitochondrial function of rats
This animal study examined A new insight into the molecular hydrogen effect on coenzyme Q and mitochondrial function of rats. The abstract describes Rat model. The abstract reports: In this paper, we demonstrated that consumption of H-rich water (HRW) resulted in stimulated rat cardiac mitochondrial electron respiratory chain function and increased levels…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline attenuates vascular smooth muscle cell proliferation and neointimal hyperplasia by inhibiting reactive oxygen species production and inactivating the Ras-ERK1/2-MEK1/2 and Akt pathways.
This animal study examined Hydrogen-rich saline attenuates vascular smooth muscle cell proliferation and neointimal hyperplasia by inhibiting reactive oxygen species production and inactivating the Ras-ERK1/2-MEK1/2 and Akt pathways. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: These results showed that hydrogen-rich saline was able to attenuate FBS-induced VSMC proliferation and neointimal hyperplasia by inhibiting ROS production and inactivating the Ras-ERK1/2-MEK1/2…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas inhalation alleviates myocardial ischemia-reperfusion injury by the inhibition of oxidative stress and NLRP3-mediated pyroptosis in rats.
This animal study examined Hydrogen gas inhalation alleviates myocardial ischemia-reperfusion injury by the inhibition of oxidative stress and NLRP3-mediated pyroptosis in rats. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: We found that oxidative stress and NLRP3 mediated pyroptosis are the important mechanisms for hydrogen to alleviate myocardial I/R injury, and we also confirmed…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAcute Effects of Molecular Hydrogen Inhalation on Exercise-Induced Oxidative Stress, Vascular Responses, and Performance in National-Level Female Rowers: An Exploratory Pilot Case Series
This case report or case series examined Acute Effects of Molecular Hydrogen Inhalation on Exercise-Induced Oxidative Stress, Vascular Responses, and Performance in National-Level Female Rowers: An Exploratory Pilot Case Series. The abstract describes Human participants; sample size 4; hydrogen delivered as hydrogen inhalation. The abstract reports: Results: Post-exercise change differences were directionally consistent across participants for HDL-C (HL +2.5 mg/dL), LDL-C (HL +6.5 mg/dL), cholinesterase (HL +10.5 U/L), and venous…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Attenuates Thyroid Hormone-Induced Cardiac Hypertrophy in Rats by regulating angiotensin II type 1 receptor and NADPH oxidase 2 mediated oxidative stress.
This animal study examined Hydrogen Attenuates Thyroid Hormone-Induced Cardiac Hypertrophy in Rats by regulating angiotensin II type 1 receptor and NADPH oxidase 2 mediated oxidative stress. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Cardiac hypertrophy occurs as a result of high levels of thyroid hormone, which may contribute to heart failure and is closely related to oxidative…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreConstitutive hydrogen inhalation prevents vascular remodeling via reduction of oxidative stress.
This animal study examined Constitutive hydrogen inhalation prevents vascular remodeling via reduction of oxidative stress. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation; reported duration 2 weeks. The abstract reports: Although the increase in superoxide anion production did not significantly differ between the hydrogen and control groups, DNA damage was decreased as a result…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffect of hydrogen-rich water on the Nrf2/ARE signaling pathway in rats with myocardial ischemia-reperfusion injury.
This animal study examined Effect of hydrogen-rich water on the Nrf2/ARE signaling pathway in rats with myocardial ischemia-reperfusion injury. The abstract describes Rat model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreA New Approach for the Prevention and Treatment of Cardiovascular Disorders. Molecular Hydrogen Significantly Reduces the Effects of Oxidative Stress.
This narrative review examined A New Approach for the Prevention and Treatment of Cardiovascular Disorders. Molecular Hydrogen Significantly Reduces the Effects of Oxidative Stress. The abstract describes Published literature review; hydrogen delivered as hydrogen water and hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Redox dysregulation and a dyshomeostasis of inflammation arise from, and result in, cellular aberrations and pathological conditions, which lead to cardiovascular diseases. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Saline Prevents Early Neurovascular Dysfunction Resulting from Inhibition of Oxidative Stress in STZ-Diabetic Rats
This animal study examined Hydrogen-Rich Saline Prevents Early Neurovascular Dysfunction Resulting from Inhibition of Oxidative Stress in STZ-Diabetic Rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Based on its inhibition of oxidative stress and up-regulation of anti-oxidative enzymes, we conclude that hydrogen-rich saline is a potentially valuable therapeutic modality for…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-containing saline alleviates pressure overload-induced interstitial fibrosis and cardiac dysfunction in rats.
This animal study examined Hydrogen-containing saline alleviates pressure overload-induced interstitial fibrosis and cardiac dysfunction in rats. The abstract describes Rat model. The abstract reports: These results indicate that HCS treatment can improve cardiac function by reducing interstitial fibrosis in pressure‑overloaded rats through its anti‑oxidative properties and via suppression…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas protects against serum and glucose deprivation‑induced myocardial injury in H9c2 cells through activation of the NF‑E2‑related factor 2/heme oxygenase 1 signaling pathway.
This animal study examined Hydrogen gas protects against serum and glucose deprivation‑induced myocardial injury in H9c2 cells through activation of the NF‑E2‑related factor 2/heme oxygenase 1 signaling pathway. The abstract describes Rat model. The abstract reports: Exposure of the cells to SGD also resulted in significant increases in HO‑1 expression and nuclear Nrf2 levels, and the HO‑1 inhibitor ZnPP IX and…. This is an automated editorial draft based on the abstract and requires source review before publication.
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