Inhalation of Hydrogen Attenuates Progression of Chronic Heart Failure via Suppression of Oxidative Stress and P53 Related to Apoptosis Pathway in Rats.
This animal study examined Inhalation of Hydrogen Attenuates Progression of Chronic Heart Failure via Suppression of Oxidative Stress and P53 Related to Apoptosis Pathway in Rats. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen protects mice against polymicrobial sepsis by ameliorating endothelial dysfunction via an Nrf2/HO-1 signaling pathway.
This animal study examined Molecular hydrogen protects mice against polymicrobial sepsis by ameliorating endothelial dysfunction via an Nrf2/HO-1 signaling pathway. The abstract describes Mouse model. The abstract reports: We found that molecular hydrogen (H2) exerts an anti-inflammatory effect. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich medium suppresses the generation of reactive oxygen species, elevates the Bcl-2/Bax ratio and inhibits advanced glycation end product-induced apoptosis.
This in vitro or cellular study examined Hydrogen-rich medium suppresses the generation of reactive oxygen species, elevates the Bcl-2/Bax ratio and inhibits advanced glycation end product-induced apoptosis. The abstract describes Endothelial cell model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen stabilizes atherosclerotic plaque in low-density lipoprotein receptor-knockout mice.
This animal study examined Molecular hydrogen stabilizes atherosclerotic plaque in low-density lipoprotein receptor-knockout mice. The abstract describes Mouse model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreConsumption of water containing over 3.5 mg of dissolved hydrogen could improve vascular endothelial function
This uncontrolled human study examined Consumption of water containing over 3.5 mg of dissolved hydrogen could improve vascular endothelial function. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: H2 may protect the vasculature from shear stress-derived detrimental ROS, such as the hydroxyl radical, by maintaining the nitric oxide-mediated vasomotor response. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen: potential in mitigating oxidative-stress-induced radiation injury .
This animal study examined Molecular hydrogen: potential in mitigating oxidative-stress-induced radiation injury. The abstract describes Rat model. The abstract reports: Uncontrolled production of oxygen and nitrogen radicals results in oxidative and nitrosative stresses that impair cellular functions and have been regarded as causative common…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen potentiates beneficial anti-infarct effect of hypoxic postconditioning in isolated rat hearts: a novel cardioprotective intervention
This animal study examined Molecular hydrogen potentiates beneficial anti-infarct effect of hypoxic postconditioning in isolated rat hearts: a novel cardioprotective intervention. The abstract describes Rat model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreChronic hydrogen-rich saline treatment attenuates vascular dysfunction in spontaneous hypertensive rats.
This uncontrolled human study examined Chronic hydrogen-rich saline treatment attenuates vascular dysfunction in spontaneous hypertensive rats. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline; reported duration 3 months. The abstract reports: Recently, it has been suggested that hydrogen exerts a therapeutic antioxidant activity by selectively reducing hydroxyl radical and peroxynitrite, the most cytotoxic chemicals of…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen (H) Inhibits Isoproterenol-Induced Cardiac Hypertrophy via Antioxidative Pathways.
This animal study examined Hydrogen (H) Inhibits Isoproterenol-Induced Cardiac Hypertrophy via Antioxidative Pathways. The abstract describes Mouse model; reported duration 7 days. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreTherapeutic efficacy of hydrogen‑rich saline alone and in combination with PI3K inhibitor in non‑small cell lung cancer.
This uncontrolled human study examined Therapeutic efficacy of hydrogen‑rich saline alone and in combination with PI3K inhibitor in non‑small cell lung cancer. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline. The abstract reports: Similarly, the results of the present study demonstrated that administration of the two agents in combination may inhibit phospho‑Akt activity, and reduce expression of…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInfluence of hydrogen-occluding-silica on migration and apoptosis in human esophageal cells in vitro
This in vitro or cellular study examined Influence of hydrogen-occluding-silica on migration and apoptosis in human esophageal cells in vitro. The abstract describes Epithelial cell model; hydrogen delivered as hydrogen water. The abstract reports: The results showed that KYSE-70 cells and HEEpiCs were generally inhibited by H-silica administration, and there was a significant proliferation-inhibitory effect in an H-silica…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtection of oral hydrogen water as an antioxidant on pulmonary hypertension
This animal study examined Protection of oral hydrogen water as an antioxidant on pulmonary hypertension. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: The results showed that the mean pulmonary arterial pressure, right ventricle weight and right ventricular hypertrophy index in MCT group were significant higher than…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreConsumption of hydrogen-rich water alleviates renal injury in spontaneous hypertensive rats.
This uncontrolled human study examined Consumption of hydrogen-rich water alleviates renal injury in spontaneous hypertensive rats. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: Recently, it has been demonstrated that hydrogen, as a novel antioxidant, can selectively reduce hydroxyl radicals and peroxynitrite anion to exert therapeutic antioxidant activity. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen ameliorates pulmonary hypertension in rats by anti-inflammatory and antioxidant effects.
This animal study examined Hydrogen ameliorates pulmonary hypertension in rats by anti-inflammatory and antioxidant effects. The abstract describes Rat model. The abstract reports: Molecular hydrogen ameliorates MCT-induced PAH in rats by suppressing macrophage accumulation, reducing oxidative stress and modulating the STAT3/NFAT axis. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreConsumption of water containing a high concentration of molecular hydrogen reduces oxidative stress and disease activity in patients with rheumatoid arthritis: an open-label pilot study.
This uncontrolled human study examined Consumption of water containing a high concentration of molecular hydrogen reduces oxidative stress and disease activity in patients with rheumatoid arthritis: an open-label pilot study. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: The results suggest that the hydroxyl radical scavenger H2 effectively reduces oxidative stress in patients with this condition. The symptoms of RA were significantly…. This is an automated editorial draft based on the abstract and requires source review before publication.
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