Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In male C57BL/6 mice, hydrogen inhalation also significantly reduced inflammatory cytokine and chemokine mRNA levels and improved oxygenation. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.
Read ArticleIn mice, hydrogen inhalation increased the survival rate to 80%, reduced LPS-induced lung damage, and decreased inflammatory cytokine release in LPS mice. These preclinical findings add evidence supporting…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Taken together, accumulating experimental evidence indicates that H₂ can significantly alleviate transplantation-related lung injury, mainly via inhibition of inflammatory cytokine…
Read ArticleA single inhalation of hydrogen for 45 min attenuated inflammatory status in airways in patients with asthma and COPD. This source-grounded publication contributes evidence relevant to molecular hydrogen…
Read ArticleIn rats, however, these variables were significantly improved in the cold ischemia with hydrogen-rich preservation solution group. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. However, a clinical trial showed that inhaling a mixture of 1.2–1.4% molecular hydrogen–air increased urinary 8-hydroxy-2′-deoxyguanosine, a marker of oxidative…
Read ArticleIn mice, the light microscope findings showed that saturated hydrogen saline reduced the impairment when compared with the saline group: Saturated hydrogen saline decreased lung edema, reduced LDH…
Read ArticleIn an animal model, hydrogen treatment during exposure to hyperoxia significantly improved blood oxygenation, reduced inflammatory events, and induced HO-1 expression. These preclinical findings add evidence supporting molecular…
Read ArticleIn male Sprague-Dawley rats, hRS administration significantly reduced the serum high-mobility group box, alanine aminotransferase, creatinine, and blood urea nitrogen levels. The pulmonary interleukin 6, high-mobility group box,…
Read ArticleIn a laboratory model, hydrogen-rich saline treatment could inhibit apoptosis and inflammation while no significant reduction was observed in nitrogen-rich saline treated animals. The authors concluded that the…
Read ArticleIn rats, administration of hydrogen-rich saline or edaravone dramatically reduced the pulmonary levels of pulmonary inflammation mediators and myeloperoxidase. These preclinical findings add evidence supporting molecular hydrogen's therapeutic…
Read ArticleThis narrative review examined this study was to investigate the hypothesis that hydrogen could ameliorate CLP-induced lung injury in rats. Hydrogen-rich saline treatment significantly attenuated lung injury as…
Read ArticleIn rats, exposure to 1.3% hydrogen significantly attenuated the upregulation of the messenger RNAs for several proinflammatory mediators induced by HS/R. Hydrogen inhalation did not affect hemodynamic status…
Read ArticleIn mice, hydrogen-rich water treatment at doses of 2.5, 5, or 10 ml/kg significantly attenuated LPS-induced pulmonary fibrosis. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential…
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