Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In rats, at P1, LPS treatment decreased expressions of genes for FGFR4, VEGFR2, and HO-1 in the lungs, and hydrogen increased expressions of these genes. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured…
Read ArticleIn male Sprague-Dawley rats, hydrogen water consumption reduced wet-to-dry weight ratio, malondialdehyde and myeloperoxidase activity and decreased the concentration of TNF-α, IL-1β, and IL-6 in the lung tissues…
Read ArticleIn male Sprague-Dawley rats, as shown in Figure 6B, the Nrf2 protein level increased significantly in the CS-challenged rat lungs as compared with that in the control (p<0.01),…
Read ArticleIn mice, hydrogen gas inhalation markedly upregulated the activity of decreased superoxide dismutase and significantly attenuated the increased level of malondialdehyde and myeloperoxidase. These preclinical findings add evidence…
Read ArticleThis narrative review examined the present review aims to provide a consistent summary of the findings of the last twenty years on the use of molecular hydrogen in…
Read ArticleIn 10 patients with chronic lung diseases due to COPD (n = 7), however, vitamin E, vitamin C, and nitrite levels showed a significant increase after 4 week…
Read ArticleThis publication is an erratum or correction associated with a molecular-hydrogen article. It does not report a new standalone experiment.
Read ArticleIn A549 and NCI-H292 cells utilized in this study were obtained from the Korean Cell Line Bank (Cancer Research Institute of Seoul National University, Seoul, Korea), H₂O₂ stimulation…
Read ArticleIn an animal model, however, BLM-induced oxidative stress was attenuated by H₂ inhalation therapy, which reduced the contents of reactive oxygen species, malondialdehyde and hydroxyproline, enhanced the activity…
Read ArticleIn rats, compared to the sham group (A), germ cellular apoptosis and lipid peroxidation in the ischemia group (B) were significantly increased with abnormal morphology and impaired spermatogenesis.…
Read ArticleIn mice, serum testosterone and FSH levels also increased, while serum ROS level decreased (all P <0.05). These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within…
Read ArticleThe results first demonstrated that long-term treatment with hydrogen-rich saline attenuated testicular oxidative level and improved male reproductive function in nicotine-treated mice. These preclinical findings add evidence supporting…
Read ArticleIn rats, although placental weight and the number of fetuses had no significant difference among groups, the placental efficiency significantly increased after the oral administration of HRW to…
Read ArticleIn a laboratory model, the expression of TNF-α was increased by 100 μmol/L vitamin C and 50 μmol/L vitamins E, separately or combined (P < 0.05), but not…
Read ArticleIn GC-1 spermatogonial cells and TM-3 Leydig cells, two well-established male reproductive cell lines, were exposed to NEMP, specifically, molecular hydrogen reduced the production of ROS and restored…
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