Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
The results demonstrated that cellular apoptosis and autophagy were significantly enhanced in the A549 and H1975 lung cancer cell lines treated with H₂. The authors concluded that increasing evidence has revealed that H₂ not only improved the side effects induced by chemotherapeutics,…
Read ArticleIn rats, semi-quantitative scoring of the lung tissue in different groups showed that the lung tissue injury score of MCT group was significantly higher than that of SHAM…
Read ArticleIn rats, the exposure of H₂ together with monocrotaline (MCT), despite individual differences between animals, tended to decrease the intrapulmonary MC population and the severity of the fibrotic…
Read ArticleIn rats, H₂ gas-treated rats exposed to CIH showed a significant reduction in 8-hydroxy-2 deoxyguanosine content and increases in superoxide dismutase activity, indicating improved oxidative stress. These preclinical…
Read ArticleIn comparison to control rats given distilled water (DW), the researchers found that HW did not significantly influence systolic blood pressure (SBP) or diastolic blood pressure (DBP) in…
Read ArticleIn male Sprague-Dawley rats, hydrogen-rich water treatment improved hemodynamics and reversed right ventricular hypertrophy. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and…
Read ArticleThis preclinical study evaluated molecular hydrogen in rats. These results are preclinical and suggest molecular hydrogen's therapeutic potential in the condition studied. Further human research is needed to…
Read ArticleIn participants with systemic lupus erythematosus (SLE), this case study suggests that molecular hydrogen therapy may be a promising treatment for patients with SLE-PAH, particularly due to its…
Read ArticleIn rats, it has also been reported that, whereas either drinking hydrogen water or intermittent inhalation of 2% H₂ gas had favorable effects in a rat model of…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Preclinical models consistently showed reductions in reactive oxygen species, inflammatory cytokines, and improved cell viability. Common limitations included small sample…
Read ArticleIn an animal model, an in vitro study performed on RAW264.7 murine cells showed that H₂ treatment prevents RANKL-associated osteoclastogenesis, inhibiting the inactivation of NF-kB, mitogen-activated protein kinase…
Read ArticleIn mice, H₂ treatment reduced inflammatory, oxidative, and fibrotic lung changes. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured…
Read ArticleIn mice, the immunofluorescence of cleaved caspase-3 also indicated that H₂ suppressed the expression of cleaved caspase-3 in TBHP-induced chondrocytes ( Figure 5H ). These preclinical findings add…
Read ArticleIn rats, mDA and 8-OHdG were significantly decreased in hydrogen-rich medium, while SOD and GSH were increased. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within…
Read ArticleIn male Sprague-Dawley rats, the wet/dry ratio increased significantly in the IR group (P < 0.01 compared with that in the sham group) and decreased significantly in IR…
Read Article